Search Results - "Real, T."

SGLT-2 (Sodium-Glucose Cotransporter 2) Inhibition Reduces Ang II (Angiotensin II)–Induced Dissecting Abdominal Aortic Aneurysm in ApoE (Apolipoprotein E) Knockout Mice by Ortega, Rebeca, Collado, Aida, Selles, Francisca, Gonzalez-Navarro, Herminia, Sanz, Maria-Jesus, Real, José T., Piqueras, Laura

“…Abdominal aortic aneurysm (AAA) is a pathological condition of permanent vessel dilatation that predisposes to the potentially fatal consequence of aortic…”
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Anthropometric Indicators as a Tool for Diagnosis of Obesity and Other Health Risk Factors: A Literature Review by Piqueras, Paola, Ballester, Alfredo, Durá-Gil, Juan V., Martinez-Hervas, Sergio, Redón, Josep, Real, José T.

“…Obesity is characterized by the accumulation of an excessive amount of fat mass (FM) in the adipose tissue, subcutaneous, or inside certain organs. The risk…”
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The Controversial Role of Vitamin D in Thyroid Cancer Prevention by Palanca, Ana, Ampudia-Blasco, Francisco Javier, Real, José T.

“…Thyroid cancer is the most common endocrine malignancy and exhibits rising incidence. Annual incidence varies by sex, age, and geographical location. It has…”
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Train-induced vibration prediction in tunnels using 2D and 3D FEM models in time domain by Real, T., Zamorano, C., Ribes, F., Real, J.I.

“…•A 3D FEM model of a railway tunnel to predict railway vibrations is developed.•The model is calibrated and validated with in situ measurements.•Two 2D FEM…”
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Adipokines in Non-Alcoholic Fatty Liver Disease: Are We on the Road toward New Biomarkers and Therapeutic Targets? by Francisco, Vera, Sanz, Maria Jesus, Real, José T., Marques, Patrice, Capuozzo, Maurizio, Ait Eldjoudi, Djedjiga, Gualillo, Oreste

“…Non-alcoholic fatty liver disease (NAFLD) has become the major cause of chronic hepatic illness and the leading indication for liver transplantation in the…”
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Beneficial effects of PCSK9 inhibition with alirocumab in familial hypercholesterolemia involve modulation of new immune players by Marques, Patrice, Domingo, Elena, Rubio, Arantxa, Martinez-Hervás, Sergio, Ascaso, Juan F., Piqueras, Laura, Real, José T., Sanz, Maria-Jesus

“…Familial hypercholesterolemia (FH) is associated with low-grade systemic inflammation, a key driver of premature atherosclerosis. We investigated the effects…”
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The GLP-1 analogue lixisenatide decreases atherosclerosis in insulin-resistant mice by modulating macrophage phenotype by Vinué, Ángela, Navarro, Jorge, Herrero-Cervera, Andrea, García-Cubas, Marta, Andrés-Blasco, Irene, Martínez-Hervás, Sergio, Real, José T., Ascaso, Juan F., González-Navarro, Herminia

“…Aims/hypothesis Recent clinical studies indicate that glucagon-like peptide-1 (GLP-1) analogues prevent acute cardiovascular events in type 2 diabetes mellitus…”
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Diagnosing Insulin Resistance by Simple Quantitative Methods in Subjects With Normal Glucose Metabolism by ASCASO, Juan F, PARDO, Susana, REAL, José T, LORENTE, Rosario I, PRIEGO, Antonia, CARMENA, Rafael

“…Diagnosing Insulin Resistance by Simple Quantitative Methods in Subjects With Normal Glucose Metabolism Juan F. Ascaso , MD , Susana Pardo , MD , José T. Real…”
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Neuropeptide FF increases M2 activation and self-renewal of adipose tissue macrophages by Waqas, Syed F Hassnain, Hoang, Anh Cuong, Lin, Ya-Tin, Ampem, Grace, Azegrouz, Hind, Balogh, Lajos, Thuróczy, Julianna, Chen, Jin-Chung, Gerling, Ivan C, Nam, Sorim, Lim, Jong-Seok, Martinez-Ibañez, Juncal, Real, José T, Paschke, Stephan, Quillet, Raphaëlle, Ayachi, Safia, Simonin, Frédéric, Schneider, E Marion, Brinkman, Jacqueline A, Lamming, Dudley W, Seroogy, Christine M, Röszer, Tamás

“…The quantity and activation state of adipose tissue macrophages (ATMs) impact the development of obesity-induced metabolic diseases. Appetite-controlling…”
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Low Muscle Mass Is Associated with Poorer Glycemic Control and Higher Oxidative Stress in Older Patients with Type 2 Diabetes by Alabadi, Blanca, Civera, Miguel, De la Rosa, Adrián, Martinez-Hervas, Sergio, Gomez-Cabrera, Mari Carmen, Real, José T

“…Body composition changes that occur during aging, such as loss of lean mass, are unfavorable at metabolic level and they can explain, in part, the appearance…”
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Association of chemokines IP-10/CXCL10 and I-TAC/CXCL11 with insulin resistance and enhance leukocyte endothelial arrest in obesity by Moreno, Beatriz, Hueso, Luisa, Ortega, Rebeca, Benito, Esther, Martínez-Hervas, Sergio, Peiro, Marta, Civera, Miguel, Sanz, María-Jesús, Piqueras, Laura, Real, José T.

“…Obesity is a key contributing factor to incidental type 2 diabetes and cardiovascular disease. CXCR3 receptor and its ligands CXCL 10 and 11 are associated…”
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Functional role of endothelial CXCL16/CXCR6-platelet-leucocyte axis in angiotensin II-associated metabolic disorders by Collado, Aida, Marques, Patrice, Escudero, Paula, Rius, Cristina, Domingo, Elena, Martinez-Hervás, Sergio, Real, José T, Ascaso, Juan F, Piqueras, Laura, Sanz, Maria-Jesus

“…Abstract Aims Angiotensin-II (Ang-II) is the main effector peptide of the renin-angiotensin system (RAS) and promotes leucocyte adhesion to the stimulated…”
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Upregulation of angiostatic chemokines IP-10/CXCL10 and I-TAC/CXCL11 in human obesity and their implication for adipose tissue angiogenesis by Hueso, Luisa, Ortega, Rebeca, Selles, Francisca, Wu-Xiong, Ning Yun, Ortega, Joaquin, Civera, Miguel, Ascaso, Juan F, Sanz, Maria-Jesus, Real, José T, Piqueras, Laura

“…Background/Aims: Impaired angiogenesis is linked to adipose tissue (AT) dysfunction, inflammation, and insulin resistance in human obesity. Chemokine (C-X-C…”
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Activation of the Constitutive Androstane Receptor Inhibits Leukocyte Adhesiveness to Dysfunctional Endothelium by López-Riera, Mireia, Ortega, Rebeca, Hueso, Luisa, Montesinos, María Carmen, Gomez-Cabrera, Mari Carmen, Sanz, María Jesús, Real, José T., Piqueras, Laura

“…Leukocyte cell recruitment into the vascular subendothelium constitutes an early event in the atherogenic process. As the effect of the constitutive androstane…”
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The nuclear retinoid‐related orphan receptor RORα controls adipose tissue inflammation in patients with morbid obesity and diabetes by Ortega, Rebeca, Hueso, Luisa, Benito, Esther, Ortega, Joaquín, Civera, Miguel, Sanz, Maria-Jesus, Real, José T., Piqueras, Laura

“…Background/aims Inflammation governs adipose tissue (AT) dysfunction in obesity. Retinoic acid receptor-related orphan receptor alpha (RORα) is associated with…”
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Frailty Is Associated with Oxidative Stress in Older Patients with Type 2 Diabetes by Alabadi, Blanca, Civera, Miguel, De la Rosa, Adrián, Martinez-Hervas, Sergio, Gomez-Cabrera, Mari Carmen, Real, José T.

“…Aging has increased the prevalence of frailty, and type 2 diabetes (T2D) has also increased in prevalence. Diabetes and oxidative stress (OS) have been shown…”
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Impact of COVID‐19 lockdown on diabetes management and follow‐up in a broad population in Spain by Palanca, Ana, Quinones‐Torrelo, Carmen, Girbés, Juan, Real, José T., Ampudia‐Blasco, F. Javier

“…Background To evaluate the impact of COVID‐19 lockdown on glycaemic control and diabetes follow‐up in a Spanish metropolitan area with a total general…”
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CCL17 and CCL22 chemokines are upregulated in human obesity and play a role in vascular dysfunction by Hueso, Luisa, Marques, Patrice, Morant, Brenda, Gonzalez-Navarro, Herminia, Ortega, Joaquin, Real, José T, Sanz, María J, Piqueras, Laura

“…Chemokines are known to play critical roles mediating inflammation in many pathophysiological processes. The aim of this study was to investigate the role of…”
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Metabolomic signature and molecular profile of normal and degenerated human intervertebral disc cells by Francisco, Vera, Ait Eldjoudi, Djedjiga, González-Rodríguez, María, Ruiz-Fernández, Clara, Cordero-Barreal, Alfonso, Marques, Patrice, Sanz, Maria Jesus, Real, José T., Lago, Francisca, Pino, Jesus, Farrag, Yousof, Gualillo, Oreste

“…Intervertebral disc degeneration (IVDD) is an incurable, specific treatment-orphan disease with an increasing burden worldwide. Although great efforts have…”
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Comparison of GLP-1 receptor agonists and other Glucose-Lowering agents on cardiovascular outcomes in individuals with type 2 diabetes and Obesity: A Spanish Real-World Population-Based study by Palanca, Ana, Ampudia-Blasco, F. Javier, Calderón, José Miguel, Sauri, Inmaculada, Martinez-Hervás, Sergio, Trillo, José Luis, Redón, Josep, Real, José T.

“…Assess the impact of glucagon-like peptide receptor agonists (GLP-1RA) compared to other glucose-lowering agents on cardiovascular outcomes in individuals with…”
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