Search Results - "Real, L M"

High frequency of potential interactions between direct‐acting antivirals and concomitant therapy in HIV/hepatitis C virus‐coinfected patients in clinical practice by Macías, J, Monge, P, Mancebo, M, Merchante, N, Neukam, K, Real, LM, Pineda, JA

“…Objectives The aim of the study was to analyse the frequency and degree of potential drug−drug interactions (DDIs) between direct‐acting antivirals (DAAs) and…”
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Incidence of recently acquired hepatitis C virus infection among HIV‐infected patients in southern Spain by Gonzalez‐Serna, A, Macias, J, Palacios, R, Gómez‐Ayerbe, C, Tellez, F, Rivero‐Juárez, A, Fernandez, M, Santos, J, Real, LM, Gonzalez‐Domenech, CM, Gomez‐Mateos, J, Pineda, JA

“…Objectives Spain is close to HCV microelimination, so rates of recently acquired HCV infection (RAHC) should decrease. Nowadays, men who have sex with men…”
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Changes in liver steatosis evaluated by transient elastography with the controlled attenuation parameter in HIV‐infected patients by Macías, J, Real, LM, Rivero‐Juárez, A, Merchante, N, Camacho, A, Neukam, K, Rivero, A, Mancebo, M, Pineda, JA

“…Objectives There are scant data on the progression of hepatic steatosis (HS) in HIV infection. We therefore evaluated changes in HS over time in HIV‐infected…”
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Fat mass and obesity‐associated gene variations are related to fatty liver disease in HIV‐infected patients by Núñez‐Torres, R, Macías, J, Rivero‐Juarez, A, Neukam, K, Merino, D, Téllez, F, Merchante, N, Gómez‐Mateos, J, Rivero, A, Pineda, JA, Real, LM

“…Objectives Fatty liver disease (FLD) is frequently observed in HIV‐infected patients. Obesity and type 2 diabetes mellitus (T2DM) are strongly associated with…”
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Association of genetic markers within the KIT and KITLG genes with human male infertility by Galan, J.J., De Felici, M., Buch, B., Rivero, M.C., Segura, A., Royo, J.L., Cruz, N., Real, L.M., Ruiz, A.

“…There is much evidence involving the KIT tyrosine kinase receptor and its ligand KITLG in the survival and proliferation of germ cells. Animal models and…”
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Identification of a 2244 base pair interstitial deletion within the human ESR1 gene in the Spanish population by Galan, J Jorge, Buch, B, Pedrinaci, S, Jimenez-Gamiz, P, Gonzalez, A, Serrano-Rios, M, Salinas, A, Rivero, M del Carmen, Real, L M, Royo, J L, Ruiz, A

“…The ESR1 AGATA haplotype is composed of five markers located within introns 5 and 6 of the human oestrogen receptor 1 (ESR1) gene. This haplotype has been…”
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GAB2 gene does not modify the risk of Alzheimer’s disease in Spanish APOE 4 carriers by Ramírez-Lorca, Reposo, Boada, M., Saez, M. E., Hernandez, I., Mauleon, A., Rosende-Roca, M., Martinez-Lage, P., Gutierrez, M., Real, L. M., Lopez-Arrieta, J., Gayan, J., Antunez, C., Gonzalez-Perez, A., Tarraga, L., Ruiz, A.

“…Objectives The genetic basis of Alzheimer’s disease (AD) is being analyzed in multiple whole genome association studies (WGAS). The GAB2 gene has been proposed…”
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Specific haplotypes of the CALPAIN-5 gene are associated with polycystic ovary syndrome by González, A., Sáez, M.E., Aragón, M.J., Galán, J.J., Vettori, P., Molina, L., Rubio, C., Real, L.M., Ruiz, Agustín, Ramírez-Lorca, R.

“…BACKGROUND: Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women of reproductive age. The aim of the present study was to investigate the…”
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Burden of significant liver damage in people living with HIV after microelimination of the hepatitis C virus by Santos, M., Corma-Gómez, A., Fernandez-Fuertes, M., González-Serna, A., Rincón, P., Real, L.M., Pineda, J.A., Macías, J.

“…•There is a high burden of liver damage in people living with HIV in the post-HCV era.•Residual injury due to prior chronic HCV infection is an outstanding…”
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Similar prevalence of hepatic steatosis among patients with chronic hepatitis C with and without HIV coinfection by Fernandez-Fuertes, M., Macías, J., Corma-Gómez, A., Rincón, P., Merchante, N., Gómez-Mateos, J., Pineda, J. A., Real, L. M.

“…Hepatic steatosis (HS) is frequently observed in HIV-infected patients. It is not known whether HIV infection is an independent risk factor for HS development…”
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Whole-genome conditional two-locus analysis identifies novel candidate genes for late-onset Parkinson’s disease by González-Pérez, A., Gayán, J., Marín, J., Galán, J. J., Sáez, M. E., Real, L. M., Antúnez, C., Ruiz, A.

“…Whole-genome epistasis analysis may add a new layer of knowledge to whole-genome association studies, permitting the identification of new candidate genes…”
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ATP5H/KCTD2 locus is associated with Alzheimer's disease risk by Boada, M, Antúnez, C, Ramírez-Lorca, R, DeStefano, A L, González-Pérez, A, Gayán, J, López-Arrieta, J, Ikram, M A, Hernández, I, Marín, J, Galán, J J, Bis, J C, Mauleón, A, Rosende-Roca, M, Moreno-Rey, C, Gudnasson, V, Morón, F J, Velasco, J, Carrasco, J M, Alegret, M, Espinosa, A, Vinyes, G, Lafuente, A, Vargas, L, Fitzpatrick, A L, Launer, L J, Sáez, M E, Vázquez, E, Becker, J T, López, O L, Serrano-Ríos, M, Tárraga, L, van Duijn, C M, Real, L M, Seshadri, S, Ruiz, A

“…To identify loci associated with Alzheimer disease, we conducted a three-stage analysis using existing genome-wide association studies (GWAS) and genotyping in…”
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Multiple mechanisms of immune evasion can coexist in melanoma tumor cell lines derived from the same patient by REAL, L. M, JIMENEZ, P, KIRKIN, A, SERRANO, A, GARCIA, A, CANTON, J, ZEUTHEN, J, GARRIDO, F, RUIZ-CABELLO, F

“…Progressive tumor growth may be associated with suppression of the immune response. Many different mechanisms may contribute to immune evasion. We investigated…”
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Unresponsiveness to interferon associated with STAT1 protein deficiency in a gastric adenocarcinoma cell line by ABRIL, E, REAL, L. M, SERRANO, A, JIMENEZ, P, GARCIA, A, CANTON, J, TRIGO, I, GARRIDO, F, RUIZ-CABELLO, F

“…HC class I expression can be up-regulated by interferons (IFN) and other cytokines. Both IFNalpha and IFNgamma have been shown to exert their effects via a…”
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Rural habitat as risk factor for hepatitis E virus seroconversion in HIV‐infected patients: A prospective longitudinal study by Rivero‐Juarez, A., Cuenca‐Lopez, F., Martinez‐Peinado, A., Camacho, A., Real, L. M., Frias, M., Gordon, A., Cantisán, S., Torre‐Cisneros, J., Pineda, J. A., Rivero, A.

“…Summary Our objective was to determine the incidence and clinical manifestations of acute hepatitis E virus (HEV) in HIV‐infected patients. A prospective…”
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Expression of HLA G in human tumors is not a frequent event by Miguel Real, Luis, Cabrera, Teresa, Collado, Antonia, Jimenez, Pilar, Garcia, Angel, Ruiz‐Cabello, Francisco, Garrido, Federico

“…Expression of HLA G may be a way for tumor cells to escape immuno‐surveillance. HLA G is selectively expressed by extravillous trophoblast in the human…”
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Association of low-density lipoprotein receptor genotypes with hepatitis C viral load by Caruz, A, Neukam, K, Rivero-Juárez, A, Herrero, R, Real, L M, Camacho, Á, Barreiro, P, Labarga, P, Rivero, A, Pineda, J A

“…Several data suggest that low-density lipoprotein receptor (LDLR) is a co-receptor for hepatitis C virus (HCV). Soluble LDLR can inhibit HCV infectivity;…”
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Impact of HIV infection on sustained virological response to treatment against hepatitis C virus with pegylated interferon plus ribavirin by Monje-Agudo, P., Castro-Iglesias, A., Rivero-Juárez, A., Martínez-Marcos, F., Ortega-González, E., Real, L. M., Pernas, B., Merchante, N., Cid, P., Macías, J., Merino, M. D., Rivero, A., Mena, A., Neukam, K., Pineda, J. A.

“…It is commonly accepted that human immunodeficiency (HIV) coinfection negatively impacts on the rates of sustained virological response (SVR) to therapy with…”
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Association of complement receptor 2 polymorphisms with innate resistance to HIV-1 infection by Herrero, R, Real, L M, Rivero-Juárez, A, Pineda, J A, Camacho, Á, Macías, J, Laplana, M, Konieczny, P, Márquez, F J, Souto, J C, Soria, J M, Saulle, I, Lo Caputo, S, Biasin, M, Rivero, A, Fibla, J, Caruz, A

“…HIV-1 induces activation of complement through the classical and lectin pathways. However, the virus incorporates several membrane-bound or soluble regulators…”
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Microsatellite instability analysis in tumors with different mechanisms for total loss of HLA expression by JIMENEZ, P, CANTON, J, CONCHA, A, CABRERA, T, FERNANDEZ, M, REAL, L. M, GARCIA, A, SERRANO, A, GARRIDO, F, RUIZ-CABELLO, F

“…Down-regulation of the expression of major histocompatibility complex molecules is a frequent event that is associated with the poor immunogenicity of tumor…”
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