Search Results - "Reagan, Jane E"
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Similarity of Synthetic Peptide from Human Tumor to Parathyroid Hormone in vivo and in vitro
Published in Science (American Association for the Advancement of Science) (11-12-1987)“…One mechanism considered responsible for the hypercalcemia that frequently accompanies malignancy is secretion by the tumor of a circulating factor that alters…”
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Addition of Alendronate to Ongoing Hormone Replacement Therapy in the Treatment of Osteoporosis: A Randomized, Controlled Clinical Trial
Published in The journal of clinical endocrinology and metabolism (01-09-1999)“…ABSTRACTAlendronate and estrogen are effective therapies for postmenopausal osteoporosis, but their efficacy and safety as combined therapy are unknown. The…”
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Modifications of position 12 in a parathyroid hormone and parathyroid hormone-related protein: toward the design of highly potent antagonists
Published in Biochemistry (Easton) (13-02-1990)“…Truncated N-terminal fragments of parathyroid hormone (PTH), [Tyr34]bovine PTH(7-34)NH2, and parathyroid hormone related protein (PTHrP), PTHrP(7-34)NH2,…”
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Addition of Alendronate to Ongoing Hormone Replacement Therapy in the Treatment of Osteoporosis: A Randomized, Controlled Clinical Trial1
Published in The journal of clinical endocrinology and metabolism (01-09-1999)“…Alendronate and estrogen are effective therapies for postmenopausal osteoporosis, but their efficacy and safety as combined therapy are unknown. The objective…”
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Acid suppression by famotidine 20 mg twice daily or 40 mg twice daily in preventing relapse of endoscopic recurrence of erosive esophagitis
Published in Clinical therapeutics (01-11-1995)“…Control of esophageal acid exposure is important in treating patients with gastroesophageal reflux disease (GERD). After complete healing of esophagitis, most…”
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A new highly potent parathyroid hormone antagonist: [D-Trp12,Tyr34]bPTH-(7-34)NH2
Published in Endocrinology (Philadelphia) (01-11-1988)“…Based upon N-terminal parathyroid hormone (PTH) analog structure-activity relationship studies, position 12 was found to possess a wide structural latitude and…”
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Evaluation of novel parathyroid hormone analogs using a bovine renal membrane receptor binding assay
Published in Endocrinology (Philadelphia) (01-09-1988)“…A PTH membrane receptor binding assay based on a stable hormone analog radioligand was refined and used with bovine renal cortical membranes to evaluate PTH…”
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Biological activity of parathyroid hormone antagonists substituted at position 13
Published in Peptides (New York, N.Y. : 1980) (01-01-1991)“…Lysine occupies position 13 in the parathyroid hormone (PTH) antagonist, [Nle8,18,Tyr34]bPTH(7-34)NH2. Acylation of the epsilon-amino group in lysine 13 by a…”
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Fasting and L-364,718 prevent cholecystokinin-induced elevations of plasma insulin levels
Published in European journal of pharmacology (01-12-1987)“…Sulfated CCK-8 but not non-sulfated CCK-8 induced a dose-dependent increase in plasma insulin levels in fed mice. In fasted mice, however, the CCK peptides…”
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Avian (chicken) parathyroid hormone: synthesis and comparative biological evaluation of the 1-34 fragment
Published in Endocrinology (Philadelphia) (01-12-1988)“…The full-length amino acid sequence of the avian (chicken) form of parathyroid hormone (cPTH) has recently been elucidated. We have chemically synthesized,…”
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A tumor-secreted protein associated with human hypercalcemia of malignancy. Biology and molecular biology
Published in Annals of the New York Academy of Sciences (1988)“…This investigation addresses a theoretical concept of tumor pathogenesis proposed over 40 years ago, namely that malignancy-associated hypercalcemia can result…”
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Effects of hydrophobic substitutions at position 18 on the potency of parathyroid hormone antagonists
Published in International journal of peptide and protein research (01-11-1990)“…Position 18 in a parathyroid hormone (PTH) antagonist, [Nle8,18,Tyr34]bPTH(7-34)NH2 (ii), was shown to tolerate substitutions by a range of amino acids with…”
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