Search Results - "Read, T. A."
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Improving Stem Cell Delivery to the Trabecular Meshwork Using Magnetic Nanoparticles
Published in Scientific reports (16-08-2018)“…Glaucoma is a major cause of blindness and is frequently associated with elevated intraocular pressure. The trabecular meshwork (TM), the tissue that primarily…”
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Transpupillary collagen photocrosslinking for targeted modulation of ocular biomechanics
Published in Biomaterials (01-04-2021)“…The central vision-threatening event in glaucoma is dysfunction and loss of retinal ganglion cells (RGCs), thought to be promoted by local tissue deformations…”
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Distinct roles for fibroblast growth factor signaling in cerebellar development and medulloblastoma
Published in Oncogene (29-08-2013)“…Cerebellar granule neurons are the most abundant neurons in the brain, and a critical element of the circuitry that controls motor coordination and learning…”
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Local endostatin treatment of gliomas administered by microencapsulated producer cells
Published in Nature biotechnology (01-01-2001)“…We describe a technique for the treatment of malignant brain tumors based on local delivery of the anti-angiogenic protein endostatin from genetically…”
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Application of an organotypic ocular perfusion model to assess intravitreal drug distribution in human and animal eyes
Published in Journal of the Royal Society interface (2022)“…Intravitreal (ITV) drug delivery is a new cornerstone for retinal therapeutics. Yet, predicting the disposition of formulations in the human eye remains a…”
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Extracellular matrix-induced cell migration from glioblastoma biopsy specimens in vitro
Published in Acta neuropathologica (01-03-1999)“…The present knowledge about the interaction between the extracellular matrix (ECM) and gliomas is mostly based on studies of permanent cell lines. Since such…”
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The glial precursor proteoglycan, NG2, is expressed on tumour neovasculature by vascular pericytes in human malignant brain tumours
Published in Neuropathology and applied neurobiology (01-10-2002)“…Glial precursor cells express NG2 and GD3 in the developing brain. These antigens are both over‐expressed during neoplasia, which suggests they may have…”
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Author Correction: Improving Stem Cell Delivery to the Trabecular Meshwork Using Magnetic Nanoparticles
Published in Scientific reports (20-02-2020)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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The glioma-associated gangliosides 3′-isoLM1, GD3 and GM2 show selective area expression in human glioblastoma xenografts in nude rat brains
Published in Neuropathology and applied neurobiology (01-12-2001)“…This work describes the in vivo expression and distribution of glioma‐associated gangliosides (GD3, GM2, 3′‐isoLM1) in a novel human brain tumour nude rat…”
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Cell therapy using encapsulated cells producing endostatin
Published in Acta neurochirurgica. Supplement (2003)“…Despite aggressive surgery and post-operative radiation and chemotherapy, the prognosis is poor for glioblastoma patients. Anti-angiogenic therapy with…”
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Cells encapsulated in alginate: a potential system for delivery of recombinant proteins to malignant brain tumours
Published in International journal of developmental neuroscience (01-08-1999)“…Growth and progression of malignant brain tumours occurs in a micromilieu consisting of both tumour and normal cells. Several proteins have been identified…”
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Alginate-encapsulated producer cells: a potential new approach for the treatment of malignant brain tumors
Published in Cell transplantation (01-11-2000)“…In recent years gene therapy has evolved as a new treatment for brain tumors, where genetically engineered cells can be used to deliver specific substances to…”
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13
Claw Transformation and Regeneration in Adult Snapping Shrimp: Test of the Inhibition Hypothesis for Maintaining Bilateral Asymmetry
Published in The Biological bulletin (Lancaster) (01-12-1997)“…In the paired asymmetric claws of adult snapping shrimp, Alpheus heterochelis, the minor, or pincer, claw may transform into a major, or snapper, claw if the…”
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Expression of extracellular matrix components in a highly infiltrative in vivo glioma model
Published in Acta neuropathologica (2003)“…This work demonstrates the expression of extracellular matrix (ECM) components in a highly infiltrative brain tumor model developed by simple inoculation of…”
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Intravital microscopy reveals novel antivascular and antitumor effects of endostatin delivered locally by alginate-encapsulated cells
Published in Cancer research (Chicago, Ill.) (15-09-2001)“…The current study describes new, antivascular, and antitumor effects of human endostatin. A novel system for continuous, localized delivery of antiangiogenic…”
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Muscle and Nerve Terminal Fine Structure of a Primitive Crustacean, the Cephalocarid Hutchinsoniella macracantha
Published in The Biological bulletin (Lancaster) (01-08-1994)“…Abdominal muscles of the cephalocarid Hutchinsoniella macracantha resemble the striated muscle fibers of other crustaceans, having regularly aligned sarcomeres…”
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Regenerate Limb Bud Sufficient for Claw Reversal in Adult Snapping Shrimps
Published in The Biological bulletin (Lancaster) (01-04-1994)“…The paired, bilaterally asymmetric snapper and pincer claws in the adult snapping shrimp Alpheus heterochelis were simultaneously autotomized at the beginning…”
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Morphology and Behavior of an Unusually Flexible Thoracic Limb in the Snapping Shrimp, Alpheus heterochelis
Published in The Biological bulletin (Lancaster) (01-08-1991)“…The second thoracic limb in the snapping shrimp, Alpheus heterochelis, is much thinner, more elongated and flexible, and has a larger ganglion than its serial…”
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Medulloblastoma Can Be Initiated by Deletion of Patched in Lineage-Restricted Progenitors or Stem Cells
Published in Cancer cell (12-08-2008)“…Medulloblastoma is the most common malignant brain tumor in children, but the cells from which it arises remain unclear. Here we examine the origin of…”
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