Search Results - "Read, Elizabeth L"
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1
Pathways of Energy Flow in LHCII from Two-Dimensional Electronic Spectroscopy
Published in The journal of physical chemistry. B (19-11-2009)“…Photosynthetic light-harvesting complexes absorb energy and guide photoexcitations to reaction centers with speed and efficacy that produce near-perfect…”
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2
Stochastic modeling reveals kinetic heterogeneity in post-replication DNA methylation
Published in PLoS computational biology (01-04-2020)“…DNA methylation is a heritable epigenetic modification that plays an essential role in mammalian development. Genomic methylation patterns are dynamically…”
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3
Hydrodynamics of transient cell-cell contact: The role of membrane permeability and active protrusion length
Published in PLoS computational biology (01-04-2019)“…In many biological settings, two or more cells come into physical contact to form a cell-cell interface. In some cases, the cell-cell contact must be…”
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4
Rare-event sampling of epigenetic landscapes and phenotype transitions
Published in PLoS computational biology (01-08-2018)“…Stochastic simulation has been a powerful tool for studying the dynamics of gene regulatory networks, particularly in terms of understanding how cell-phenotype…”
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5
DNA-Binding Kinetics Determines the Mechanism of Noise-Induced Switching in Gene Networks
Published in Biophysical journal (20-10-2015)“…Gene regulatory networks are multistable dynamical systems in which attractor states represent cell phenotypes. Spontaneous, noise-induced transitions between…”
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6
Analysis of Single-Cell Gene Pair Coexpression Landscapes by Stochastic Kinetic Modeling Reveals Gene-Pair Interactions in Development
Published in Frontiers in genetics (31-01-2020)“…Single-cell transcriptomics is advancing discovery of the molecular determinants of cell identity, while spurring development of novel data analysis methods…”
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7
Two-Dimensional Electronic Spectroscopy of the B800-B820 Light-Harvesting Complex
Published in Proceedings of the National Academy of Sciences - PNAS (22-08-2006)“…Emerging nonlinear optical spectroscopies enable deeper insight into the intricate world of interactions and dynamics of complex molecular systems. 2D…”
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8
Cross-peak-specific two-dimensional electronic spectroscopy
Published in Proceedings of the National Academy of Sciences - PNAS (04-09-2007)“…Intermolecular electronic coupling dictates the optical properties of molecular aggregate systems. Of particular interest are photosynthetic pigment-protein…”
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9
Visualization of Excitonic Structure in the Fenna-Matthews-Olson Photosynthetic Complex by Polarization-Dependent Two-Dimensional Electronic Spectroscopy
Published in Biophysical journal (01-07-2008)“…Photosynthetic light-harvesting proceeds by the collection and highly efficient transfer of energy through a network of pigment-protein complexes…”
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10
Stochastic effects are important in intrahost HIV evolution even when viral loads are high
Published in Proceedings of the National Academy of Sciences - PNAS (27-11-2012)“…Blood plasma viral loads and the time to progress to AIDS differ widely among untreated HIV-infected humans. Although people with certain HLA (HLA-I) alleles…”
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11
Simulation of receptor triggering by kinetic segregation shows role of oligomers and close contacts
Published in Biophysical journal (03-05-2022)“…The activation of T cells, key players of the immune system, involves local evacuation of phosphatase CD45 from a region of the T cell’s surface, segregating…”
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12
Regulation of macrophage polarization and plasticity by complex activation signals
Published in Integrative biology (Cambridge) (12-09-2016)“…Macrophages are versatile cells of the immune system that play an important role in both advancing and resolving inflammation. Macrophage activation has been…”
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13
Locally correlated kinetics of post-replication DNA methylation reveals processivity and region specificity in DNA methylation maintenance
Published in Journal of the Royal Society interface (26-10-2022)“…DNA methylation occurs predominantly on cytosine-phosphate-guanine (CpG) dinucleotides in the mammalian genome, and the methylation landscape is maintained…”
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14
Evidence for wavelike energy transfer through quantum coherence in photosynthetic systems
Published in Nature (12-04-2007)“…Photosynthetic complexes are exquisitely tuned to capture solar light efficiently, and then transmit the excitation energy to reaction centres, where long term…”
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15
Effects of thymic selection of the T-cell repertoire on HLA class I-associated control of HIV infection
Published in Nature (20-05-2010)“…Without therapy, most people infected with human immunodeficiency virus (HIV) ultimately progress to AIDS. Rare individuals ('elite controllers') maintain very…”
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16
Solving Immunology?
Published in Trends in immunology (01-02-2017)“…Emergent responses of the immune system result from the integration of molecular and cellular networks over time and across multiple organs. High-content and…”
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17
Hypoxia induces lytic replication of Kaposi sarcoma–associated herpesvirus
Published in Blood (15-05-2001)“…There is substantial evidence that Kaposi sarcoma–associated herpesvirus (KSHV) plays an important role in the pathogenesis of all forms of Kaposi sarcoma…”
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18
Markov State Models of gene regulatory networks
Published in BMC systems biology (06-02-2017)“…Gene regulatory networks with dynamics characterized by multiple stable states underlie cell fate-decisions. Quantitative models that can link molecular-level…”
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19
Photon echo studies of photosynthetic light harvesting
Published in Photosynthesis research (01-09-2009)“…The broad linewidths in absorption spectra of photosynthetic complexes obscure information related to their structure and function. Photon echo techniques…”
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20
Pigment Organization and Energy Level Structure in Light-Harvesting Complex 4: Insights from Two-Dimensional Electronic Spectroscopy
Published in The journal of physical chemistry. B (07-05-2009)“…Photosynthetic light-harvesting antennae direct energy collected from sunlight to reaction centers with remarkable efficiency and rapidity. Despite their…”
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