Search Results - "Rea, Philip A"

Phytochelatin synthase: of a protease a peptide polymerase made by Rea, Philip A.

“…Of the mechanisms known to protect vascular plants and some algae, fungi and invertebrates from the toxic effects of non‐essential heavy metals such as As, Cd…”
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Plant ATP-Binding Cassette Transporters by Rea, P.A

“…The ATP-binding cassette (ABC) protein superfamily is one of the largest known, with over 120 members in both Arabidopsis thaliana and rice (Oryza sativa)…”
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Arsenic tolerance in Arabidopsis is mediated by two ABCC-type phytochelatin transporters by Song, Won-Yong, Park, Jiyoung, Mendoza-Cózatl, David G., Suter-Grotemeyer, Marianne, Shim, Donghwan, Hörtensteiner, Stefan, Geisler, Markus, Weder, Barbara, Rea, Philip A., Rentsch, Doris, Schroeder, Julian I., Lee, Youngsook, Martinoia, Enrico, Koornneef, Maarten

“…Arsenic is an extremely toxic metalloid causing serious health problems. In Southeast Asia, aquifers providing drinking and agricultural water for tens of…”
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Adaptive Engineering of Phytochelatin-based Heavy Metal Tolerance by Cahoon, Rebecca E., Lutke, W. Kevin, Cameron, Jeffrey C., Chen, Sixue, Lee, Soon Goo, Rivard, Rebecca S., Rea, Philip A., Jez, Joseph M.

“…Metabolic engineering approaches are increasingly employed for environmental applications. Because phytochelatins (PC) protect plants from heavy metal…”
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Functional Characterization of AtATM1, AtATM2, and AtATM3, a Subfamily of Arabidopsis Half-molecule ATP-binding Cassette Transporters Implicated in Iron Homeostasis by Chen, Sixue, Sánchez-Fernández, Rociío, Lyver, Elise R., Dancis, Andrew, Rea, Philip A.

“…The functional capabilities of one of the smallest subfamilies of ATP-binding cassette transporters from Arabidopsis thaliana, the AtATMs, are described…”
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Plant Vacuolar ATP-binding Cassette Transporters That Translocate Folates and Antifolates in Vitro and Contribute to Antifolate Tolerance in Vivo by Raichaudhuri, Ayan, Peng, Mingsheng, Naponelli, Valeria, Chen, Sixue, Sánchez-Fernández, Rocío, Gu, Honglan, Gregory, Jesse F., Hanson, Andrew D., Rea, Philip A.

“…The vacuoles of pea (Pisum sativum) leaves and red beet (Beta vulgaris) storage root are major sites for the intracellular compartmentation of folates. In the…”
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AtPCS1, a Phytochelatin Synthase from Arabidopsis: Isolation and in vitro Reconstitution by Vatamaniuk, Olena K., Mari, Stéphane, Lu, Yu-Ping, Rea, Philip A.

“…Phytochelatins, a class of posttranslationally synthesized peptides, play a pivotal role in heavy metal, primarily Cd2+ tolerance in plants and fungi by…”
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Transcriptome analysis of root transporters reveals participation of multiple gene families in the response to cation stress by Maathuis, Frans J. M., Filatov, Victor, Herzyk, Pawel, C. Krijger, Gerard, B. Axelsen, Kristian, Chen, Sixue, Green, Brian J., Li, Yi, Madagan, Kathryn L., Sánchez‐Fernández, Rocío, Forde, Brian G., Palmgren, Michael G., Rea, Philip A., Williams, Lorraine E., Sanders, Dale, Amtmann, Anna

“…Summary Plant nutrition critically depends on the activity of membrane transporters that translocate minerals from the soil into the plant and are responsible…”
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Weeds, worms, and more. Papain's long-lost cousin, phytochelatin synthase by Rea, P.A, Vatamaniuk, O.K, Rigden, D.J

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CeHMT-1, a Putative Phytochelatin Transporter, Is Required for Cadmium Tolerance in Caenorhabditis elegans by Vatamaniuk, Olena K., Bucher, Elizabeth A., Sundaram, Meera V., Rea, Philip A.

“…Phytochelatins (PCs), (γ-Glu-Cys)n Gly polymers that were formerly considered to be restricted to plants and some fungal systems, are now known to play a…”
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Phytochelatin Synthase, Papain's Cousin, in Stereo by Rea, Philip A.

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Mutagenic Definition of a Papain-like Catalytic Triad, Sufficiency of the N-Terminal Domain for Single-Site Core Catalytic Enzyme Acylation, and C-Terminal Domain for Augmentative Metal Activation of a Eukaryotic Phytochelatin Synthase by Romanyuk, Nataliya D., Rigden, Daniel J., Vatamaniuk, Olena K., Lang, Albert, Cahoon, Rebecca E., Jez, Joseph M., Rea, Philip A.

“…Phytochelatin (PC) synthases are γ-glutamylcysteine (γ-Glu-Cys) dipeptidyl transpeptidases that catalyze the synthesis of heavy metal-binding PCs, ($\gamma…”
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A new pathway for vacuolar cadmium sequestration in Saccharomyces cerevisiae: YCF1-catalyzed transport of bis(glutathionato)cadmium by Li, Z.S. (University of Pennsylvania, Philadelphia, PA.), Lu, Y.P, Zhen, R.G, Szczypka, M, Thiele, D.J, Rea, P.A

“…The yeast cadmium factor (YCF1) gene encodes an MgATP-energized glutathione S-conjugate transporter responsible for the vacuolar sequestration of organic…”
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From vacuolar GS-X pumps to multispecific ABC transporters by Rea, P.A. (University of Pennsylvania, Philadelphia, PA.), Li, Z.S, Lu, Y.P, Drozdowicz, Y.M, Martinoia, E

“…While the concept of H+-coupling has dominated studies of energy-dependent organic solute transport in plants for over two decades, recent studies have…”
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Plant ABC proteins – a unified nomenclature and updated inventory by Verrier, Paul J., Bird, David, Burla, Bo, Dassa, Elie, Forestier, Cyrille, Geisler, Markus, Klein, Markus, Kolukisaoglu, Üner, Lee, Youngsook, Martinoia, Enrico, Murphy, Angus, Rea, Philip A., Samuels, Lacey, Schulz, Burkhard, Spalding, Edgar P., Yazaki, Kazufumi, Theodoulou, Frederica L.

“…The ABC superfamily comprises both membrane-bound transporters and soluble proteins involved in a broad range of processes, many of which are of considerable…”
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Alternate Energy-Dependent Pathways for the Vacuolar Uptake of Glucose and Glutathione Conjugates by Dolores M. Bartholomew, Drew E. Van Dyk, Sze-Mei Cindy Lau, O'Keefe, Daniel P., Rea, Philip A., Viitanen, Paul V.

“…Through the development and application of a liquid chromatography-mass spectrometry-based procedure for measuring the transport of complex organic molecules…”
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AVP2, a Sequence-Divergent, K⁺-Insensitive H⁺-Translocating Inorganic Pyrophosphatase from Arabidopsis by Drozdowicz, Yolanda M., Kissinger, Jessica C., Rea, Philip A.

“…Plant vacuolar H+-translocating inorganic pyrophosphatases (V-PPases; EC 3.6.1.1) have been considered to constitute a family of functionally and structurally…”
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Localization, Regulation, and Substrate Transport Properties of Bpt1p, a Saccharomyces cerevisiae MRP-Type ABC Transporter by Sharma, Kailash Gulshan, Mason, Deborah L, Liu, Guosheng, Rea, Philip A, Bachhawat, Anand K, Michaelis, Susan

“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Metformin: Out of Backwaters and into the Mainstream by Rea, Philip A., Tien, Anderson Y.

“…Metformin has come to prominence despite a checkered history. Its story is one of delays, uncertainties, and dead ends, as well as fortuitous accidents. It is…”
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Can skinny fat beat obesity? Newly discovered in adult mammals, beige fat cells can switch between accumulating fat and burning it, depending on metabolic needs by Rea, Philip A, Yin, Peter, Zahalka, Ryan

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