Search Results - "Re:GEN open"

Clinical Value of Patient-Reported Outcomes for People Living with HIV: Mini-Review by Yoshino, Yusuke, Kimura, Yoshitaka

“…Background: This mini-review examines the clinical significance of patient-reported outcomes (PROs) in the care of individuals living with HIV (PLWH), focusing…”
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Predicting Potential miRNA Targets for Antibody Glycosylation in CHO Cells Using a Simplified Evaluation Workflow by Schlossbauer, Patrick, Klingler, Florian, Hesse, Friedemann

“…Introduction: In the past decade, microRNAs (miRNAs), which are small, noncoding RNAs of ∼22 nucleotides length, have gained attention as novel engineering…”
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Electroporation of CRISPR/Cas9 Targeting Neurogenin 3 (NGN3) in Porcine Embryos and Its Effects on Mosaicism and Off-Target Effects by Next Generation Sequencing (NGS) by Park, Insung, Navarro-Serna, Sergio, Pinho, Raquel M., Berger, Trish, Maga, Elizabeth A., Gadea, Joaquín, Kim, Seung K., Ross, Pablo J.

“…Introduction: CRISPR/Cas9-mediated editing of embryos through microinjection is limited in efficiency because of high rates of mosaicism and off-target…”
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Direct Plasmid DNA Transfection into Differentiated Mouse C2C12 Myotubes by Conniff, Amanda Sales, Cason, Aneeshea, Alvarado, Juliana Gonzalez, Bhandary, Manya, Patel, Shreena, Singh, Julie, Heller, Richard, Heller, Loree C.

“…Background: Models of muscle cell culture allow simple manipulation to optimize gene transfer experiments, offering a significant opportunity to model muscle…”
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Analysis of Testosterone Binding with Cytochrome P450 11?-Hydroxylase and Its Variants Through Computational Approach by Sonika Kar, T.S. Sreevidya, Rucha Y. Hebalkar, Pratibha Kushwaha, Balasubramanian Senthilkumaran, N. Prakash Prabhu

“…Background: Cytochrome P450 11?-hydroxylase (H11b) converts testosterone (T) into 11-hydroxytestosterone. In Clarias batrachus (catfish), H11b occurs in…”
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R263K Mutation Leading to Failure of Dolutegravir-Based Treatment in a HIV Patient also Receiving Rifampicin: A Case Report by Li, Jin, Wen, Zhiwei, Chen, Yili, Yin, Sichun

“…Background: Cases of treatment failure in patients developing the R263K mutation have been previously reported. Here we present a patient who developed…”
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NF-κB Pathway Analysis and Biomarker Identification in Nasopharyngeal Carcinoma by Salam, Dayang-Sharyati D.A., San, Hwang Siaw, Bhave, Mrinal, Theng, Lau Bee, Wezen, Xavier Chee

“…Background: Nasopharyngeal carcinoma (NPC) is a form of head and neck cancer that is endemic in most parts of Asia. Etiological factors for NPC include genetic…”
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NF-?B Pathway Analysis and Biomarker Identification in Nasopharyngeal Carcinoma by Dayang-Sharyati D.A. Salam, Hwang Siaw San, Lau Bee Theng, Xavier Chee Wezen

“…Background: Nasopharyngeal carcinoma (NPC) is a form of head and neck cancer that is endemic in most parts of Asia. Etiological factors for NPC include genetic…”
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Analysis of Testosterone Binding with Cytochrome P450 11β-Hydroxylase and Its Variants Through Computational Approach by Kar, Sonika, Sreevidya, T.S., Hebalkar, Rucha Y., Kushwaha, Pratibha, Senthilkumaran, Balasubramanian, Prabhu, N. Prakash

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Mapping the Accessory Proteins (Orfs) of Severe Acute Respiratory Syndrome Coronavirus 2 by Thomas, Sunil

“…Background: The coronavirus disease 2019 (COVID-19) pandemic, first observed in December 2019 caused by severe acute respiratory syndrome coronavirus 2…”
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Myopic Shift After the Administration of Omidenepag Isopropyl in Patients with Normal-Tension Glaucoma by Inoue, Kenji, Kunimatsu-Sanuki, Shiho, Ishida, Kyoko, Tomita, Goji

“…Purpose : To evaluate myopic shift after the administration of omidenepag isopropyl (OMDI) in patients with normal-tension glaucoma (NTG). Methods : In this…”
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Identification of p53-R175H Q167 and R248 as Residues Most Involved in Its Interaction with Plakoglobin by Lo, Chu Shiun, Omar, Sara Ibrahim, Chang, Jinlan, Bassey-Archibong, Blessing, A Tuszynski, Jack, Jahroudi, Nadia, Pasdar, Manijeh

“…Background: The conformational p53-R175H is the most frequently occurring p53 mutant in cancers and a focus of mutant p53 targeted therapies. Plakoglobin is a…”
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Optimum Use of Human AB Serum for Monocyte-Differentiated Macrophages (MDMs) Isolated from Healthy Individuals by Sharma, N., Kumar, M. Madhan, Mohanty, K. K., Khandelwal, V.

“…Background: For studying in vitro immune responses, peripheral blood mononuclear cells (PBMCs) and its immune cell components isolated from human blood are…”
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Dynamical Systems Models for Plasma Dilution by Chambers, Dylan, Christensen, Neil

“…Introduction: Recent experiments provide evidence that diluting the blood plasma restores the plasma environment to a more youthful level at least partially…”
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Mutation Reduction of Alopecia-Related Genes in hiPSC Using miR-520d-5p by Miura, Norimasa, Miura, Keigo

“…Background: iPSCs, with many mutations or epigenetic modifications, are in a unique aging state and have pluripotent properties. Previously, we reported that…”
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NRP1 and Furin as Putative Mediators of SARS-CoV-2 Entry into Human Brain Cells by Kumar, Ashutosh, Narayan, Ravi K., Kumar, Sujeet, Pareek, Vikas, Kumari, Chiman, Jha, Rakesh K., Prasoon, Pranav

“…Background: Coronavirus disease 2019 (COVID-19) has prominent neurological manifestations, including psychiatric symptoms, indicating a significant synaptic…”
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Genetic Analysis of Blastocyst from Metaphase I like Oocytes with Indented Zone Pellucida by Jiang, Yan, Song, Ge, Yuan, Jing-Chuan, Miao, Sui-Bing

“…Background : Previous cases reported that oocytes were characterized by indented zone pellucida (ZP) and narrow perivitelline space (PVS) with low oocyte…”
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Identification of NUDT153 Variant in the Bangladeshi Population using Allele-Specific PCR by Sarker, Drishty Badhon, Akash, Md. Mahmudul Hasan, Sajib, Abu Ashfaqur, Akhteruzzaman, Sharif

“…Background : Thiopurines are a class of immunosuppressive drugs that are often the mainstay of treatment for diverse immunological and malignant conditions…”
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Screening for Acute HIV Infection in Fortaleza, Brazil: What Would Be the Best Strategy? by Bandeira, Luciana Pinto, Galvão, Natália Gimeniz, Alves, Lucas Pinho, Marques Magalhães, Ana Séfora, de Assis Custódio, Richeyla Kelly, de Barros Carlos, Luciana Maria, Matsuda, Elaine Monteiro, de Macedo Brígido, Luís Fernando, Lima, Danielle Malta, Baima Colares, Jeová Keny

“…Brazil is considered a middle-income country, where human immunodeficiency virus (HIV) transmission and morbidity/mortality indicators have shown relative…”
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Analysis of SARS-CoV-2 Mutations in the Context of Epitope Affinity for HLA Class I and Class II Most Frequent in Russia Alleles by Vasileva, Anastasia A., Kazakova, Polina G., Mitrofanov, Sergey I., Akhmerova, Yuliya N., Golubnikova, Liliya A., Grammatikati, Konstantin S., Zemsky, Pavel U., Pilipenko, Maria N., Sergeev, Andrey P., Smirnova, Nadezhda V., Frolova, Lidiya V., Frolovskaya, Alesya A., Shpakova, Tatyana A., Makarov, Valentin V., Keskinov, Anton A., Yudin, Vladimir S., Yudin, Sergey M., Skvortsova, Veronika I.

“…Since the first news about the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) appeared, a large amount of data on the variability of…”
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