Search Results - "Raziuddin, Arati"
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Characterization of tumor evolution by functional clonality and phylogenetics in hepatocellular carcinoma
Published in Communications biology (29-03-2024)“…Hepatocellular carcinoma (HCC) is a molecularly heterogeneous solid malignancy, and its fitness may be shaped by how its tumor cells evolve. However, ability…”
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2
The proteasome inhibitor PS-341 sensitizes neoplastic cells to TRAIL-mediated apoptosis by reducing levels of c-FLIP
Published in Blood (01-07-2003)“…Because of the pivotal role the proteasome plays in apoptosis, inhibitors of this enzyme, such as PS-341, provide a great opportunity for exploring synergy…”
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3
Immunobiology of natural killer cells and bone marrow transplantation: merging of basic and preclinical studies
Published in Immunological reviews (01-07-2001)“…Natural killer (NK) cells mediate acute rejection of bone marrow, but not solid tissue, allografts in lethally irradiated mice. Precisely how and why this…”
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Increased bone marrow allograft rejection by depletion of NK cells expressing inhibitory Ly49 NK receptors for donor class I antigens
Published in Blood (15-10-2002)“…Natural killer (NK) cells are the major effectors of acute rejection of incompatible bone marrow cell (BMC) grafts in lethally irradiated mice. The…”
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5
Differential effects of the rejection of bone marrow allografts by the depletion of activating versus inhibiting Ly-49 natural killer cell subsets
Published in The Journal of immunology (1950) (01-01-1998)“…Natural killer cells mediate the specific rejection of bone marrow cell (BMC) allografts in lethally irradiated mice. The Ly-49 family of molecules present on…”
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6
Toward best practice in cancer mutation detection with whole-genome and whole-exome sequencing
Published in Nature biotechnology (01-09-2021)“…Clinical applications of precision oncology require accurate tests that can distinguish true cancer-specific mutations from errors introduced at each step of…”
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7
Establishing community reference samples, data and call sets for benchmarking cancer mutation detection using whole-genome sequencing
Published in Nature biotechnology (01-09-2021)“…The lack of samples for generating standardized DNA datasets for setting up a sequencing pipeline or benchmarking the performance of different algorithms…”
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8
Cancer and neurologic degeneration in xeroderma pigmentosum: long term follow-up characterises the role of DNA repair
Published in Journal of medical genetics (01-03-2011)“…The frequency of cancer, neurologic degeneration and mortality in xeroderma pigmentosum (XP) patients with defective DNA repair was determined in a four decade…”
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9
Augmentation of antitumor effects by NK cell inhibitory receptor blockade in vitro and in vivo
Published in Blood (15-05-2001)“…Subsets of natural killer (NK) cells are characterized by the expression of inhibitory and/or stimulatory receptors specific for major histocompatibility…”
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10
Ly-49 receptor expression and functional analysis in multiple mouse strains
Published in Journal of leukocyte biology (01-09-1999)“…We present data on the strain distribution and functional characteristics of the Ly‐49 receptors A, C/I, D, and G2 on DX5+ natural killer (NK) cells. We have…”
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11
Recombinant Human Growth Hormone Promotes Hematopoietic Reconstitution after Syngeneic Bone Marrow Transplantation in Mice
Published in Stem cells (Dayton, Ohio) (01-01-1998)“…Recombinant human growth hormone (rhGH) was administered to mice after syngeneic bone marrow transplantation (BMT) to determine its effect on hematopoietic…”
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12
Synergistic effects of in vivo depletion of Ly-49A and Ly-49G2 natural killer cell subsets in the rejection of H2(b) bone marrow cell allografts
Published in Blood (15-06-2000)“…Subsets of murine natural killer (NK) cells exist that express the Ly-49 family of molecules that recognize different major histocompatibility complex (MHC)…”
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13
Synergistic effects of in vivo depletion of Ly-49A and Ly-49G2 natural killer cell subsets in the rejection of H2b bone marrow cell allografts
Published in Blood (15-06-2000)“…Subsets of murine natural killer (NK) cells exist that express the Ly-49 family of molecules that recognize different major histocompatibility complex (MHC)…”
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14
Prolactin exerts hematopoietic growth-promoting effects in vivo and partially counteracts myelosuppression by azidothymidine
Published in Experimental hematology (01-05-1999)“…Prolactin (PRL) is a neuroendocrine hormone that influences immune and hematopoietic development. The mechanism of action of this hormone in vivo remains…”
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15
A c-erbB-2 Promoter-specific Nuclear Matrix Protein from Human Breast Tumor Tissues Mediates NF-κB DNA Binding Activity
Published in The Journal of biological chemistry (20-06-1997)“…The c-erbB-2 gene overexpression plays a major role in the pathogenesis of breast cancer. Binding studies detected a nuclear matrix protein (NMP) in human…”
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A c-erbB-2 Promoter-specific Nuclear Matrix Protein from Human Breast Tumor Tissues Mediates NF-κB DNA Binding Activity
Published in The Journal of biological chemistry (20-06-1997)“…The c-erbB-2 gene overexpression plays a major role in the pathogenesis of breast cancer. Binding studies detected a nuclear matrix protein (NMP) in human…”
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17
Synergistic effects of in vivo depletion of Ly-49A and Ly-49G2 natural killer cell subsets in the rejection of H2b bone marrow cell allografts
Published in Blood (15-06-2000)“…Abstract Subsets of murine natural killer (NK) cells exist that express the Ly-49 family of molecules that recognize different major histocompatibility complex…”
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18
Ly-49 G2+ NK cells are responsible for mediating the rejection of H-2b bone marrow allog rafts in mice
Published in International immunology (01-12-1996)“…NK cells can mediate the specific rejection of bone marrow but not solid tissue allografts in lethally irradiated mice. NK cells are also responsible for the…”
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19
Ly-49 G2 + NK cells are responsible for mediating the rejection of H-2 b bone marrow allog rafts in mice
Published in International immunology (1996)Get full text
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20
Ly-49 G2+ NK cells are responsible for mediating the rejection of H-2b bone marrow allografts in mice
Published in International immunology (01-12-1996)“…NK cells can mediate the specific rejection of bone marrow but not solid tissue allografts in lethally irradiated mice. NK cells are also responsible for the…”
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