Search Results - "Razak, A. A."

Translation-relevant EEG phenotypes in a mouse model of Fragile X Syndrome by Lovelace, Jonathan W., Ethell, Iryna M., Binder, Devin K., Razak, Khaleel A.

“…Identification of comparable biomarkers in humans and validated animal models will facilitate pre-clinical to clinical therapeutic pipelines to treat…”
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Safety, pharmacokinetics, and antitumor activity of the anti-CEACAM5-DM4 antibody–drug conjugate tusamitamab ravtansine (SAR408701) in patients with advanced solid tumors: first-in-human dose-escalation study by Gazzah, A., Bedard, P.L., Hierro, C., Kang, Y.-K., Abdul Razak, A., Ryu, M.-H., Demers, B., Fagniez, N., Henry, C., Hospitel, M., Soria, J.-C., Tabernero, J.

“…Tusamitamab ravtansine (SAR408701) is an antibody–drug conjugate composed of a humanized monoclonal antibody that binds carcinoembryonic antigen-related cell…”
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Genetic Reduction of Matrix Metalloproteinase-9 Promotes Formation of Perineuronal Nets Around Parvalbumin-Expressing Interneurons and Normalizes Auditory Cortex Responses in Developing Fmr1 Knock-Out Mice by Wen, Teresa H, Afroz, Sonia, Reinhard, Sarah M, Palacios, Arnold R, Tapia, Kendal, Binder, Devin K, Razak, Khaleel A, Ethell, Iryna M

“…Abstract Abnormal sensory responses associated with Fragile X Syndrome (FXS) and autism spectrum disorders include hypersensitivity and impaired habituation to…”
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A systematic review of immune-related adverse event reporting in clinical trials of immune checkpoint inhibitors by Chen, T W, Razak, A R, Bedard, P L, Siu, L L, Hansen, A R

“…There are limited data about the quality of immune-related adverse event (irAE) reporting in immune checkpoint inhibitor (ICI) clinical trial publications. A…”
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Volume guarantee pressure support ventilation in extremely preterm infants and neurodevelopmental outcome at 18 months by Razak, A

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Age of acquisition of 299 words in seven languages: American English, Czech, Gaelic, Lebanese Arabic, Malay, Persian and Western Armenian by Łuniewska, Magdalena, Wodniecka, Zofia, Miller, Carol A, Smolík, Filip, Butcher, Morna, Chondrogianni, Vasiliki, Hreich, Edith Kouba, Messarra, Camille, A Razak, Rogayah, Treffers-Daller, Jeanine, Yap, Ngee Thai, Abboud, Layal, Talebi, Ali, Gureghian, Maribel, Tuller, Laurice, Haman, Ewa

“…We present a new set of subjective Age of Acquisition (AoA) ratings for 299 words (158 nouns, 141 verbs) in seven languages from various language families and…”
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The Perineuronal 'Safety' Net? Perineuronal Net Abnormalities in Neurological Disorders by Wen, Teresa H, Binder, Devin K, Ethell, Iryna M, Razak, Khaleel A

“…Perineuronal nets (PNN) are extracellular matrix (ECM) assemblies that preferentially ensheath parvalbumin (PV) expressing interneurons. Converging evidence…”
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A phase Ib dose-escalation study of the MEK inhibitor trametinib in combination with the PI3K/mTOR inhibitor GSK2126458 in patients with advanced solid tumors by Grilley-Olson, J. E., Bedard, P. L., Fasolo, A., Cornfeld, M., Cartee, L., Razak, A. R. Abdul, Stayner, L.-A., Wu, Y., Greenwood, R., Singh, R., Lee, C. B., Bendell, J., Burris, H. A., Del Conte, G., Sessa, C., Infante, J. R.

“…Summary Introduction This Phase Ib trial investigated the safety, tolerability, and recommended phase 2 dose for the pan-PI3K/mTOR inhibitor, GSK2126458…”
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Turbulence Model Selection for Low Reynolds Number Flows by Aftab, S M A, Mohd Rafie, A S, Razak, N A, Ahmad, K A

“…One of the major flow phenomena associated with low Reynolds number flow is the formation of separation bubbles on an airfoil's surface. NACA4415 airfoil is…”
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Immunotherapy in soft-tissue sarcoma by Ayodele, O, Razak, A R Abdul

“…Soft-tissue sarcoma (sts) is a rare mesenchymal malignancy that accounts for less than 1% of all adult tumours. Despite the successful advancement of localized…”
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Acute pharmacological inhibition of matrix metalloproteinase‐9 activity during development restores perineuronal net formation and normalizes auditory processing in Fmr1 KO mice by Pirbhoy, Patricia S., Rais, Maham, Lovelace, Jonathan W., Woodard, Walker, Razak, Khaleel A., Binder, Devin K., Ethell, Iryna M.

“…Individuals with Fragile X Syndrome (FXS) and autism spectrum disorder (ASD) exhibit cognitive impairments, social deficits, increased anxiety, and sensory…”
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Multielectrode array analysis of EEG biomarkers in a mouse model of Fragile X Syndrome by Jonak, Carrie R., Lovelace, Jonathan W., Ethell, Iryna M., Razak, Khaleel A., Binder, Devin K.

“…Fragile X Syndrome (FXS) is a leading known genetic cause of intellectual disability with symptoms that include increased anxiety and social and sensory…”
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Synthesis and optical properties of CuO nanostructures obtained via a novel thermal decomposition method by Al-Gaashani, R., Radiman, S., Tabet, N., Razak Daud, A.

“…• CuO nanostructures as a powder were produced by one-step thermal decomposition. • A new method to synthesize and control nanostructured CuO is reported. •…”
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A phase II trial of dacomitinib, an oral pan-human EGF receptor (HER) inhibitor, as first-line treatment in recurrent and/or metastatic squamous-cell carcinoma of the head and neck by Abdul Razak, A.R., Soulières, D., Laurie, S.A., Hotte, S.J., Singh, S., Winquist, E., Chia, S., Le Tourneau, C., Nguyen-Tan, P.- F., Chen, E.X., Chan, K.K., Wang, T., Giri, N., Mormont, C., Quinn, S., Siu, L.L.

“…An open-label, multicenter, single-arm phase II trial was conducted to investigate the clinical activity of dacomitinib in recurrent/metastatic squamous-cell…”
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Stock price volatility during the COVID-19 pandemic: The GARCH model by Endri, Endri, Aipama, Widya, Razak, A., Sari, Laynita, Septiano, Renil

“…This study examined the response of stock prices on the Indonesia Stock Exchange (IDX) to COVID-19 using an event study approach and the GARCH model. The…”
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Smallholdings with high oil palm yield also support high bird species richness and diverse feeding guilds by Razak, Syafiq A, Saadun, Norzanalia, Azhar, Badrul, Lindenmayer, David B

“…Biodiversity has been devastated globally in the past hundred years, largely because of land conversion and agricultural intensification. Conversion of…”
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Silicone elastomers with covalently incorporated aromatic voltage stabilisers by Razak, A. H. A., Skov, A. L.

“…When optimising dielectric elastomers (DEs) a conflict exists, namely that for large achievable actuation strains softness is required, but with increased…”
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Developmental studies in fragile X syndrome by Razak, Khaleel A, Dominick, Kelli C, Erickson, Craig A

“…Fragile X syndrome (FXS) is the most common single gene cause of autism and intellectual disabilities. Humans with FXS exhibit increased anxiety, sensory…”
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Ten-year trend in prevalence and outcome of Down syndrome with congenital heart disease in a middle-income country by Zahari, Norazah, Mat Bah, Mohd Nizam, A. Razak, Hasliza, Thong, Meow-Keong

“…Limited data are available on the survival of patients with Down syndrome and congenital heart disease (CHD) from middle-income countries. This retrospective…”
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A Review of Machine Learning Methods of Feature Selection and Classification for Autism Spectrum Disorder by Rahman, Md Mokhlesur, Usman, Opeyemi Lateef, Muniyandi, Ravie Chandren, Sahran, Shahnorbanun, Mohamed, Suziyani, Razak, Rogayah A

“…Autism Spectrum Disorder (ASD), according to DSM-5 in the American Psychiatric Association, is a neurodevelopmental disorder that includes deficits of social…”
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