Search Results - "Raynal, Noël Jm"

Importance of dose-schedule of 5-aza-2'-deoxycytidine for epigenetic therapy of cancer by Lemaire, Maryse, Chabot, Guy G, Raynal, Noël Jm, Momparler, Louise F, Hurtubise, Annie, Bernstein, Mark L, Momparler, Richard L

“…The inactivation of tumor suppressor genes (TSGs) by aberrant DNA methylation plays an important role in the development of malignancy. Since this epigenetic…”
Get full text

Hypomethylation of TET2 Target Genes Identifies a Curable Subset of Acute Myeloid Leukemia by Yamazaki, Jumpei, Taby, Rodolphe, Jelinek, Jaroslav, Raynal, Noel J M, Cesaroni, Matteo, Pierce, Sherry A, Kornblau, Steven M, Bueso-Ramos, Carlos E, Ravandi, Farhad, Kantarjian, Hagop M, Issa, Jean-Pierre J

“…Acute myeloid leukemia (AML) is curable in a subset of cases. The DNA methylation regulator TET2 is frequently mutated in AML, and we hypothesized that…”
Get full text