Search Results - "Rayhan, Ashyad"
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Pacybara: accurate long-read sequencing for barcoded mutagenized allelic libraries
Published in Bioinformatics (Oxford, England) (29-03-2024)“…Abstract Motivation Long-read sequencing technologies, an attractive solution for many applications, often suffer from higher error rates. Alignment of…”
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A Comprehensive, Flexible Collection of SARS-CoV-2 Coding Regions
Published in G3 : genes - genomes - genetics (01-09-2020)“…The world is facing a global pandemic of COVID-19 caused by the SARS-CoV-2 coronavirus. Here we describe a collection of codon-optimized coding sequences for…”
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A resource of human coronavirus protein-coding sequences in a flexible, multipurpose Gateway Entry clone collection
Published in G3 : genes - genomes - genetics (05-07-2023)“…Abstract The COVID-19 pandemic has catalyzed unprecedented scientific data and reagent sharing and collaboration, which enabled understanding the virology of…”
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Using genetic buffering relationships identified in fission yeast to reveal susceptibilities in cells lacking hamartin or tuberin function
Published in Biology open (01-01-2018)“…Tuberous sclerosis complex is an autosomal dominant disorder characterized by benign tumors arising from the abnormal activation of mTOR signaling in cells…”
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LARGE-SCALE TESTING OF AGXT MISSENSE VARIANT EFFECTS
Published in Molecular genetics and metabolism (01-03-2023)Get full text
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LARGE-SCALE TESTING OF MISSENSE VARIANT EFFECTS
Published in Molecular genetics and metabolism (01-03-2023)Get full text
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A proteome-scale map of the SARS-CoV-2–human contactome
Published in Nature biotechnology (01-01-2023)“…Understanding the mechanisms of coronavirus disease 2019 (COVID-19) disease severity to efficiently design therapies for emerging virus variants remains an…”
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Journal Article Web Resource -
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Exploiting Fission Yeast Genetic Interaction Data to Identify Disease-Specific Drug Targets for Tuberous Sclerosis Complex
Published 01-01-2017“…Tuberous sclerosis complex (TSC) is an inherited genetic disorder caused by loss-of-function mutations in either TSC1 or TSC2. Their respective gene products…”
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Dissertation