Search Results - "Rayego, Sandra"

Targeting the progression of chronic kidney disease by Ruiz-Ortega, Marta, Rayego-Mateos, Sandra, Lamas, Santiago, Ortiz, Alberto, Rodrigues-Diez, Raul R.

“…Chronic kidney disease (CKD) is a devastating condition that is reaching epidemic levels owing to the increasing prevalence of diabetes mellitus, hypertension…”
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Statins: Could an old friend help in the fight against COVID‐19? by Rodrigues‐Diez, Raul R., Tejera‐Muñoz, Antonio, Marquez‐Exposito, Laura, Rayego‐Mateos, Sandra, Santos Sanchez, Laura, Marchant, Vanessa, Tejedor Santamaria, Lucía, Ramos, Adrian M., Ortiz, Alberto, Egido, Jesus, Ruiz‐Ortega, Marta

“…The COVID‐19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has overwhelmed healthcare systems requiring the rapid…”
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Connective tissue growth factor induces renal fibrosis via epidermal growth factor receptor activation by Rayego‐Mateos, Sandra, Morgado‐Pascual, José Luis, Rodrigues‐Diez, Raúl R, Rodrigues‐Diez, Raquel, Falke, Lucas L, Mezzano, Sergio, Ortiz, Alberto, Egido, Jesús, Goldschmeding, Roel, Ruiz‐Ortega, Marta

“…Connective tissue growth factor (CCN2/CTGF) is a matricellular protein that is overexpressed in progressive human renal diseases, mainly in fibrotic areas. In…”
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STING1 deficiency ameliorates immune-mediated crescentic glomerulonephritis in mice by García-Giménez, Jorge, Córdoba-David, Gina, Rayego-Mateos, Sandra, Cannata-Ortiz, Pablo, Carrasco, Susana, Ruiz-Ortega, Marta, Fernandez-Fernandez, Beatriz, Ortiz, Alberto, Ramos, Adrián M

“…Rapidly progressive/crescentic glomerulonephritis (RPGN/CGN) involves the formation of glomerular crescents by maladaptive differentiation of parietal…”
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Intravascular hemolysis triggers NAFLD characterized by a deregulation of lipid metabolism and lipophagy blockade by Rayego‐Mateos, Sandra, Morgado‐Pascual, José Luis, García‐Caballero, Cristina, Lazaro, Iolanda, Sala‐Vila, Aleix, Opazo‐Rios, Lucas, Mas‐Fontao, Sebastian, Egido, Jesús, Ruiz‐Ortega, Marta, Moreno, Juan Antonio

“…Intravascular hemolysis is a common feature of different clinical entities, including sickle cell disease and malaria. Chronic hemolytic disorders are…”
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Role of Toll‐like receptor 4 in intravascular hemolysis‐mediated injury by Vázquez‐Carballo, Cristina, Herencia, Carmen, Guerrero‐Hue, Melania, García‐Caballero, Cristina, Rayego‐Mateos, Sandra, Morgado‐Pascual, José Luis, Opazo‐Rios, Lucas, González‐Guerrero, Cristian, Vallejo‐Mudarra, Mercedes, Cortegano, Isabel, Gaspar, María Luisa, Andrés, Belén, Egido, Jesús, Moreno, Juan Antonio

“…Massive intravascular hemolysis is a common characteristic of several pathologies. It is associated with the release of large quantities of heme into the…”
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Targeting inflammation to treat diabetic kidney disease: the road to 2030 by Rayego-Mateos, Sandra, Rodrigues-Diez, Raul R, Fernandez-Fernandez, Beatriz, Mora-Fernández, Carmen, Marchant, Vanessa, Donate-Correa, Javier, Navarro-González, Juan F, Ortiz, Alberto, Ruiz-Ortega, Marta

“…Diabetic kidney disease (DKD) is one of the fastest growing causes of chronic kidney disease and associated morbidity and mortality. Preclinical research has…”
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CCN2 Increases TGF-β Receptor Type II Expression in Vascular Smooth Muscle Cells: Essential Role of CCN2 in the TGF-β Pathway Regulation by Tejera-Muñoz, Antonio, Marquez-Exposito, Laura, Tejedor-Santamaría, Lucía, Rayego-Mateos, Sandra, Orejudo, Macarena, Suarez-Álvarez, Beatriz, López-Larrea, Carlos, Ruíz-Ortega, Marta, Rodrigues-Díez, Raúl R

“…The cellular communication network factor 2 (CCN2/CTGF) has been traditionally described as a mediator of the fibrotic responses induced by other factors…”
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Pathogenic Pathways and Therapeutic Approaches Targeting Inflammation in Diabetic Nephropathy by Rayego-Mateos, Sandra, Morgado-Pascual, José Luis, Opazo-Ríos, Lucas, Guerrero-Hue, Melania, García-Caballero, Cristina, Vázquez-Carballo, Cristina, Mas, Sebastián, Sanz, Ana Belén, Herencia, Carmen, Mezzano, Sergio, Gómez-Guerrero, Carmen, Moreno, Juan Antonio, Egido, Jesús

“…Diabetic nephropathy (DN) is associated with an increased morbidity and mortality, resulting in elevated cost for public health systems. DN is the main cause…”
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PTEN Deletion in Adult Mice Induces Hypoinsulinemia With Concomitant Low Glucose Levels by Crespo-Masip, Maria, Pérez-Gómez, Aurora, Guzmán, Carla, Rayego, Sandra, Doladé, Nuria, García-Carrasco, Alicia, Jover, Ramiro, Valdivielso, José Manuel

“…The PI3K/AKT pathway, negatively regulated by PTEN, plays a paramount role in glucose metabolism regulation due to its activation by the insulin receptor…”
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Bromodomain and Extraterminal Proteins as Novel Epigenetic Targets for Renal Diseases by Morgado-Pascual, Jose Luis, Rayego-Mateos, Sandra, Tejedor, Lucia, Suarez-Alvarez, Beatriz, Ruiz-Ortega, Marta

“…Epigenetic mechanisms, especially DNA methylation and histone modifications, are dynamic processes that regulate the gene expression transcriptional program in…”
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Role of Epidermal Growth Factor Receptor (EGFR) and Its Ligands in Kidney Inflammation and Damage by Ruiz-Ortega, Marta, Valdivielso, José Manuel, Valentijn, Floris, Morgado-Pascual, Jose Luis, Rodrigues-Diez, Raul, Rayego-Mateos, Sandra, Goldschmeding, Roel

“…Chronic kidney disease (CKD) is characterized by persistent inflammation and progressive fibrosis, ultimately leading to end-stage renal disease. Although many…”
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Bisphenol A Modulates Autophagy and Exacerbates Chronic Kidney Damage in Mice by Priego, Alberto Ruiz, Parra, Emilio González, Mas, Sebastián, Morgado-Pascual, José Luis, Ruiz-Ortega, Marta, Rayego-Mateos, Sandra

“…Bisphenol A (BPA) is a ubiquitous environmental toxin that accumulates in chronic kidney disease (CKD). Our aim was to explore the effect of chronic exposition…”
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Molecular Mechanisms of Kidney Injury and Repair by Rayego-Mateos, Sandra, Marquez-Expósito, Laura, Rodrigues-Diez, Raquel, Sanz, Ana B, Guiteras, Roser, Doladé, Nuria, Rubio-Soto, Irene, Manonelles, Anna, Codina, Sergi, Ortiz, Alberto, Cruzado, Josep M, Ruiz-Ortega, Marta, Sola, Anna

“…Chronic kidney disease (CKD) will become the fifth global cause of death by 2040, thus emphasizing the need to better understand the molecular mechanisms of…”
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IL-17A as a Potential Therapeutic Target for Patients on Peritoneal Dialysis by Marchant, Vanessa, Tejera-Muñoz, Antonio, Marquez-Expósito, Laura, Rayego-Mateos, Sandra, Rodrigues-Diez, Raul R, Tejedor, Lucia, Santos-Sanchez, Laura, Egido, Jesús, Ortiz, Alberto, Valdivielso, Jose M, Fraser, Donald J, López-Cabrera, Manuel, Selgas, Rafael, Ruiz-Ortega, Marta

“…Chronic kidney disease (CKD) is a health problem reaching epidemic proportions. There is no cure for CKD, and patients may progress to end-stage renal disease…”
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Toll-Like Receptors in Acute Kidney Injury by Vázquez-Carballo, Cristina, Guerrero-Hue, Melania, García-Caballero, Cristina, Rayego-Mateos, Sandra, Opazo-Ríos, Lucas, Morgado-Pascual, José Luis, Herencia-Bellido, Carmen, Vallejo-Mudarra, Mercedes, Cortegano, Isabel, Gaspar, María Luisa, de Andrés, Belén, Egido, Jesús, Moreno, Juan Antonio

“…Acute kidney injury (AKI) is an important health problem, affecting 13.3 million individuals/year. It is associated with increased mortality, mainly in low-…”
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CCN2 (Cellular Communication Network Factor 2) Deletion Alters Vascular Integrity and Function Predisposing to Aneurysm Formation by Rodrigues-Díez, Raúl R., Tejera-Muñoz, Antonio, Esteban, Vanesa, Steffensen, Lasse B., Rodrigues-Díez, Raquel, Orejudo, Macarena, Rayego-Mateos, Sandra, Falke, Lucas L., Cannata-Ortiz, Pablo, Ortiz, Alberto, Egido, Jesus, Mallat, Ziad, Briones Ana, M., Bajo, M. Auxiliadora, Goldschmeding, Roel, Ruiz-Ortega, Marta

“…CCN2 (cellular communication network factor 2) is a matricellular protein involved in cell communication and microenvironmental signaling responses. CCN2 is…”
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Non-Coding RNAs in Kidney Diseases: The Long and Short of Them by Moreno, Juan Antonio, Hamza, Eya, Guerrero-Hue, Melania, Rayego-Mateos, Sandra, García-Caballero, Cristina, Vallejo-Mudarra, Mercedes, Metzinger, Laurent, Metzinger-Le Meuth, Valérie

“…Recent progress in genomic research has highlighted the genome to be much more transcribed than expected. The formerly so-called junk DNA encodes a…”
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Mitochondrial Dysfunction in the Cardio-Renal Axis by Mendez-Barbero, Nerea, Oller, Jorge, Sanz, Ana B, Ramos, Adrian M, Ortiz, Alberto, Ruiz-Ortega, Marta, Rayego-Mateos, Sandra

“…Cardiovascular disease (CVD) frequently complicates chronic kidney disease (CKD). The risk of all-cause mortality increases from 20% to 500% in patients who…”
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Epigenetic Modification Mechanisms Involved in Inflammation and Fibrosis in Renal Pathology by Rayego-Mateos, Sandra, Ruiz-Ortega, Marta, Kerr, Bredford, Suarez-Alvarez, Beatriz, Dolade, Nuria, Rodrigues-Diez, Raul, Marchant, Vanessa, Morgado-Pascual, Jose Luis, Valdivielso, José Manuel

“…The growing incidence of obesity, hypertension, and diabetes, coupled with the aging of the population, is increasing the prevalence of renal diseases in our…”
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