Search Results - "Rayavarapu, Sree"

Endoplasmic Reticulum Stress in Skeletal Muscle Homeostasis and Disease by Rayavarapu, Sree, Coley, William, Nagaraju, Kanneboyina

“…Our appreciation of the role of endoplasmic reticulum (ER) stress pathways in both skeletal muscle homeostasis and the progression of muscle diseases is…”
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Discovery of serum protein biomarkers in the mdx mouse model and cross-species comparison to Duchenne muscular dystrophy patients by Hathout, Yetrib, Marathi, Ramya L, Rayavarapu, Sree, Zhang, Aiping, Brown, Kristy J, Seol, Haeri, Gordish-Dressman, Heather, Cirak, Sebahattin, Bello, Luca, Nagaraju, Kanneboyina, Partridge, Terry, Hoffman, Eric P, Takeda, Shin'ichi, Mah, Jean K, Henricson, Erik, McDonald, Craig

“…It is expected that serum protein biomarkers in Duchenne muscular dystrophy (DMD) will reflect disease pathogenesis, progression and aid future therapy…”
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Identification of Disease Specific Pathways Using in Vivo SILAC Proteomics in Dystrophin Deficient mdx Mouse by Rayavarapu, Sree, Coley, William, Cakir, Erdinc, Jahnke, Vanessa, Takeda, Shin'ichi, Aoki, Yoshitsugu, Grodish-Dressman, Heather, Jaiswal, Jyoti K., Hoffman, Eric P., Brown, Kristy J., Hathout, Yetrib, Nagaraju, Kanneboyina

“…Duchenne muscular dystrophy (DMD) is an X-linked neuromuscular disorder caused by a mutation in the dystrophin gene. DMD is characterized by progressive…”
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Role of non-immune mechanisms of muscle damage in idiopathic inflammatory myopathies by Coley, William, Rayavarapu, Sree, Nagaraju, Kanneboyina

“…Idiopathic inflammatory myopathies (IIMs) comprise a group of autoimmune diseases that are characterized by symmetrical skeletal muscle weakness and muscle…”
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Use of Quantitative Membrane Proteomics Identifies a Novel Role of Mitochondria in Healing Injured Muscles by Sharma, Nimisha, Medikayala, Sushma, Defour, Aurelia, Rayavarapu, Sree, Brown, Kristy J., Hathout, Yetrib, Jaiswal, Jyoti K.

“…Skeletal muscles are proficient at healing from a variety of injuries. Healing occurs in two phases, early and late phase. Early phase involves healing the…”
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Effect of the IL-1 Receptor Antagonist Kineret® on Disease Phenotype in mdx Mice by Benny Klimek, Margaret E, Sali, Arpana, Rayavarapu, Sree, Van der Meulen, Jack H, Nagaraju, Kanneboyina

“…Duchenne muscular dystrophy (DMD) is an X-linked muscle disease caused by mutations in the dystrophin gene. The pathology of DMD manifests in patients with…”
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Idiopathic inflammatory myopathies: pathogenic mechanisms of muscle weakness by Rayavarapu, Sree, Coley, William, Kinder, Travis B, Nagaraju, Kanneboyina

“…Idiopathic inflammatory myopathies (IIMs) are a heterogenous group of complex muscle diseases of unknown etiology. These diseases are characterized by…”
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The molecular basis of skeletal muscle weakness in a mouse model of inflammatory myopathy by Coley, William, Rayavarapu, Sree, Pandey, Gouri S., Sabina, Richard L., Van der Meulen, Jack H., Ampong, Beryl, Wortmann, Robert L., Rawat, Rashmi, Nagaraju, Kanneboyina

“…Objective It is generally believed that muscle weakness in patients with polymyositis and dermatomyositis is due to autoimmune and inflammatory processes…”
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Omigapil treatment decreases fibrosis and improves respiratory rate in dy(2J) mouse model of congenital muscular dystrophy by Yu, Qing, Sali, Arpana, Van der Meulen, Jack, Creeden, Brittany K, Gordish-Dressman, Heather, Rutkowski, Anne, Rayavarapu, Sree, Uaesoontrachoon, Kitipong, Huynh, Tony, Nagaraju, Kanneboyina, Spurney, Christopher F

“…Congenital muscular dystrophy is a distinct group of diseases presenting with weakness in infancy or childhood and no current therapy. One form, MDC1A, is the…”
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Mitochondria mediate cell membrane repair and contribute to Duchenne muscular dystrophy by Vila, Maria C, Rayavarapu, Sree, Hogarth, Marshall W, Van der Meulen, Jack H, Horn, Adam, Defour, Aurelia, Takeda, Shin’ichi, Brown, Kristy J, Hathout, Yetrib, Nagaraju, Kanneboyina, Jaiswal, Jyoti K

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The effects of MyD88 deficiency on disease phenotype in dysferlin-deficient A/J mice: role of endogenous TLR ligands by Uaesoontrachoon, Kitipong, Cha, Hee-Jae, Ampong, Beryl, Sali, Arpana, Vandermeulen, Jack, Wei, Benjamin, Creeden, Brittany, Huynh, Tony, Quinn, James, Tatem, Kathleen, Rayavarapu, Sree, Hoffman, Eric P, Nagaraju, Kanneboyina

“…An absence of dysferlin leads to activation of innate immune receptors such as Toll‐like receptors (TLRs) and skeletal muscle inflammation. Myeloid…”
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Characterization of dysferlin deficient SJL/J mice to assess preclinical drug efficacy: fasudil exacerbates muscle disease phenotype by Rayavarapu, Sree, Van der Meulen, Jack H, Gordish-Dressman, Heather, Hoffman, Eric P, Nagaraju, Kanneboyina, Knoblach, Susan M

“…The dysferlin deficient SJL/J mouse strain is commonly used to study dysferlin deficient myopathies. Therefore, we systematically evaluated behavior in…”
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Daily supplementation of D-ribose shows no therapeutic benefits in the MHC-I transgenic mouse model of inflammatory myositis by Coley, William, Rayavarapu, Sree, van der Meulen, Jack H, Duba, Ayyappa S, Nagaraju, Kanneboyina

“…Current treatments for idiopathic inflammatory myopathies (collectively called myositis) focus on the suppression of an autoimmune inflammatory response within…”
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The use of urinary and kidney SILAM proteomics to monitor kidney response to high dose morpholino oligonucleotides in the mdx mouse by Zhang, Aiping, Uaesoontrachoon, Kitipong, Shaughnessy, Conner, Das, Jharna R, Rayavarapu, Sree, Brown, Kristy J, Ray, Patricio E, Nagaraju, Kanneboyina, van den Anker, John N, Hoffman, Eric P, Hathout, Yetrib

“…Phosphorodiamidate morpholino oligonucleotides (PMO) are used as a promising exon-skipping gene therapy for Duchenne Muscular Dystrophy (DMD). One potential…”
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Glucocorticoid analogues: potential therapeutic alternatives for treating inflammatory muscle diseases by Reeves, Erica K M, Rayavarapu, Sree, Damsker, Jesse M, Nagaraju, Kanneboyina

“…Glucocorticoids (GCs) have been prescribed to treat a variety of diseases, including inflammatory myopathies and Duchenne muscular dystrophy for over 50 years…”
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Effect of genetic background on the dystrophic phenotype in mdx mice by Coley, William D, Bogdanik, Laurent, Vila, Maria Candida, Yu, Qing, Van Der Meulen, Jack H, Rayavarapu, Sree, Novak, James S, Nearing, Marie, Quinn, James L, Saunders, Allison, Dolan, Connor, Andrews, Whitney, Lammert, Catherine, Austin, Andrew, Partridge, Terence A, Cox, Gregory A, Lutz, Cathleen, Nagaraju, Kanneboyina

“…Genetic background significantly affects phenotype in multiple mouse models of human diseases, including muscular dystrophy. This phenotypic variability is…”
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Mitochondria mediate cell membrane repair and contribute to Duchenne muscular dystrophy by Vila, Maria C, Rayavarapu, Sree, Hogarth, Marshall W, Van der Meulen, Jack H, Horn, Adam, Defour, Aurelia, Takeda, Shin’ichi, Brown, Kristy J, Hathout, Yetrib, Nagaraju, Kanneboyina, Jaiswal, Jyoti K

“…Dystrophin deficiency is the genetic basis for Duchenne muscular dystrophy (DMD), but the cellular basis of progressive myofiber death in DMD is not fully…”
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An update on pathogenic mechanisms of inflammatory myopathies by Rayavarapu, Sree, Coley, William, Nagaraju, Kanneboyina

“…PURPOSE OF REVIEWOur understanding of the pathogenesis of the inflammatory myopathies suggests an interplay between adaptive, innate immune, and nonimmune…”
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Effect of the IL-1 Receptor Antagonist Kineret.sup.® on Disease Phenotype in mdx Mice by Benny Klimek, Margaret E, Sali, Arpana, Rayavarapu, Sree, Van der Meulen, Jack H, Nagaraju, Kanneboyina

“…Duchenne muscular dystrophy (DMD) is an X-linked muscle disease caused by mutations in the dystrophin gene. The pathology of DMD manifests in patients with…”
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AMP‐activated protein kinase signaling regulated expression of urea cycle enzymes in response to changes in dietary protein intake by Heibel, Sandra K., McGuire, Peter J., Haskins, Nantaporn, Majumdar, Himani D., Rayavarapu, Sree, Nagaraju, Kanneboyina, Hathout, Yetrib, Brown, Kristy, Tuchman, Mendel, Caldovic, Ljubica

“…Abundance of urea cycle enzymes in the liver is regulated by dietary protein intake. Although urea cycle enzyme levels rise in response to a high‐protein (HP)…”
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