Search Results - "Ray, Swapan K."

Targeting autophagy for combating chemoresistance and radioresistance in glioblastoma by Taylor, Matthew A., Das, Bhaskar C., Ray, Swapan K.

“…Autophagy is an evolutionarily conserved catabolic process that plays an essential role in maintaining cellular homeostasis by degrading unneeded cell…”
Get full text

Role of pro-inflammatory cytokines released from microglia in neurodegenerative diseases by Smith, Joshua A, Das, Arabinda, Ray, Swapan K, Banik, Naren L

“…Highlights ► Evidence suggests involvement of pro-inflammatory cytokines in neurodegeneration. ► Pro-inflammatory cytokines are released from activated…”
Get full text

Synergistic anti-tumor actions of luteolin and silibinin prevented cell migration and invasion and induced apoptosis in glioblastoma SNB19 cells and glioblastoma stem cells by Chakrabarti, Mrinmay, Ray, Swapan K

“…Abstract Glioblastoma is the most lethal brain tumor. Failure of conventional chemotherapies prompted the search for natural compounds for treatment of…”
Get full text

Modulation of autophagy for neuroprotection and functional recovery in traumatic spinal cord injury by Ray, Swapan

“…Spinal cord injury (SCI) is a serious central nervous system trauma that leads to loss of motor and sensory functions in the SCI patients. One of the cell…”
Get full text

Ceramide and Sphingosine Regulation of Myelinogenesis: Targeting Serine Palmitoyltransferase Using microRNA in Multiple Sclerosis by Dasgupta, Somsankar, Ray, Swapan K

“…Ceramide and sphingosine display a unique profile during brain development, indicating their critical role in myelinogenesis. Employing advanced technology…”
Get full text

Retinoic acid signaling pathways in development and diseases by Das, Bhaskar C., Thapa, Pritam, Karki, Radha, Das, Sasmita, Mahapatra, Sweta, Liu, Ting-Chun, Torregroza, Ingrid, Wallace, Darren P., Kambhampati, Suman, Van Veldhuizen, Peter, Verma, Amit, Ray, Swapan K., Evans, Todd

“…This graphical abstract represents the chemical structures of retinoic acid and several synthetic derivative retinoids, the use of these chemicals for probing…”
Get full text

Estrogen receptor agonists for attenuation of neuroinflammation and neurodegeneration by Chakrabarti, Mrinmay, Haque, Azizul, Banik, Naren L, Nagarkatti, Prakash, Nagarkatti, Mitzi, Ray, Swapan K

“…Highlights • Estrogen receptor (ER) agonists play crucial roles in the immune system and the CNS. • Cell signaling pathways are modulated by ER agonists via…”
Get full text

Spinal Cord Injury: A Review of Current Therapy, Future Treatments, and Basic Science Frontiers by Varma, Abhay K., Das, Arabinda, Wallace, Gerald, Barry, John, Vertegel, Alexey A., Ray, Swapan K., Banik, Naren L.

“…The incidence of acute and chronic spinal cord injury (SCI) in the United States is more than 10,000 per year, resulting in 720 cases per million persons…”
Get full text

miR-138 overexpression is more powerful than hTERT knockdown to potentiate apigenin for apoptosis in neuroblastoma in vitro and in vivo by Chakrabarti, Mrinmay, Banik, Naren L., Ray, Swapan K.

“…Decrease in expression of the tumor suppressor microRNA-138 (miR-138) correlates well with an increase in telomerase activity in many human cancers. The…”
Get full text

Applications of CRISPR-Cas9 Technology to Genome Editing in Glioblastoma Multiforme by Al-Sammarraie, Nadia, Ray, Swapan K.

“…Glioblastoma multiforme (GBM) is an aggressive malignancy of the brain and spinal cord with a poor life expectancy. The low survivability of GBM patients can…”
Get full text

Intersections of Ubiquitin-Proteosome System and Autophagy in Promoting Growth of Glioblastoma Multiforme: Challenges and Opportunities by Visintin, Rhett, Ray, Swapan K

“…Glioblastoma multiforme (GBM) is a brain tumor notorious for its propensity to recur after the standard treatments of surgical resection, ionizing radiation…”
Get full text

miR-30e Blocks Autophagy and Acts Synergistically with Proanthocyanidin for Inhibition of AVEN and BIRC6 to Increase Apoptosis in Glioblastoma Stem Cells and Glioblastoma SNB19 Cells by Chakrabarti, Mrinmay, Klionsky, Daniel J, Ray, Swapan K

“…Glioblastoma is the most common and malignant brain tumor in humans. It is a heterogeneous tumor harboring glioblastoma stem cells (GSC) and other glioblastoma…”
Get full text

Epigallocatechin-3-Gallate and Genistein for Decreasing Gut Dysbiosis, Inhibiting Inflammasomes, and Aiding Autophagy in Alzheimer's Disease by Muraleedharan, Ahalya, Ray, Swapan K

“…There are approximately 24 million cases of Alzheimer's disease (AD) worldwide, and the number of cases is expected to increase four-fold by 2050. AD is a…”
Get full text

Potential therapeutic roles of retinoids for prevention of neuroinflammation and neurodegeneration in Alzheimer's disease by Das, Bhaskar, Dasgupta, Somsankar, Ray, Swapan

“…All retinoids, which can be natural and synthetic, are chemically related to vitamin A. Both natural and synthetic retinoids use specific nuclear receptors…”
Get full text

Advanced Bioinformatics Analysis and Genetic Technologies for Targeting Autophagy in Glioblastoma Multiforme by Manea, Amanda J, Ray, Swapan K

“…As the most malignant primary brain tumor in adults, a diagnosis of glioblastoma multiforme (GBM) continues to carry a poor prognosis. GBM is characterized by…”
Get full text

Administration of low dose estrogen attenuates persistent inflammation, promotes angiogenesis, and improves locomotor function following chronic spinal cord injury in rats by Samantaray, Supriti, Das, Arabinda, Matzelle, Denise C., Yu, Shan P., Wei, Ling, Varma, Abhay, Ray, Swapan K., Banik, Naren L.

“…Spinal cord injury (SCI) causes loss of neurological function and, depending upon the severity of injury, may lead to paralysis. Currently, no FDA‐approved…”
Get full text

Photofrin based photodynamic therapy and miR-99a transfection inhibited FGFR3 and PI3K/Akt signaling mechanisms to control growth of human glioblastoma In vitro and in vivo by Chakrabarti, Mrinmay, Banik, Naren L, Ray, Swapan K

“…Glioblastoma is the most common malignant brain tumor in humans. We explored the molecular mechanisms how the efficacy of photofrin based photodynamic therapy…”
Get full text

Alterations in expression of specific microRNAs by combination of 4-HPR and EGCG inhibited growth of human malignant neuroblastoma cells by Chakrabarti, Mrinmay, Khandkar, Mehrab, Banik, Naren L, Ray, Swapan K

“…Abstract Malignant neuroblastomas are childhood tumors that remain mostly incurable. We explored efficacy of N-(4-hydroxyphenyl) retinamide (4-HPR) and…”
Get full text

Overexpression of miR-7-1 Increases Efficacy of Green Tea Polyphenols for Induction of Apoptosis in Human Malignant Neuroblastoma SH-SY5Y and SK-N-DZ Cells by Chakrabarti, Mrinmay, Ai, Walden, Banik, Naren L., Ray, Swapan K.

“…Neuroblastoma is an extracranial solid tumor that usually occurs in infants and children. Malignant neuroblastomas remain mostly refractory to currently…”
Get full text

Garlic compounds generate reactive oxygen species leading to activation of stress kinases and cysteine proteases for apoptosis in human glioblastoma T98G and U87MG cells by Das, Arabinda, Banik, Naren L., Ray, Swapan K.

“…BACKGROUND. Garlic‐derived organosulfur compounds such as diallyl sulfide (DAS), diallyl disulfide (DADS), and diallyl trisulfide (DATS) provide significant…”
Get full text