Search Results - "Ray, Sidhartha D."

Highly Bioavailable Forms of Curcumin and Promising Avenues for Curcumin-Based Research and Application: A Review by Stohs, Sidney J, Chen, Oliver, Ray, Sidhartha D, Ji, Jin, Bucci, Luke R, Preuss, Harry G

“…Curcumin exerts a wide range of beneficial physiological and pharmacological activities, including antioxidant, anti-amyloid, anti-inflammatory,…”
Get full text

p‐Synephrine, ephedrine, p‐octopamine and m‐synephrine: Comparative mechanistic, physiological and pharmacological properties by Stohs, Sidney J., Shara, Mohd, Ray, Sidhartha D.

“…Confusion and misunderstanding exist regarding the lack of cardiovascular and other adverse health effects of p‐synephrine and p‐octopamine relative to…”
Get full text

New Perspectives on the Efficacy of Gallic Acid in Cosmetics & Nanocosmeceuticals by Khan, Barkat Ali, Mahmood, Tariq, Menaa, Farid, Shahzad, Yasser, Yousaf, Abid Mehmood, Hussain, Talib, Ray, Sidhartha D

“…Gallic acid (GA-3,4,5-trihydroxybenzoic acid), a phenolic phytochemical, is a ubiquitous secondary metabolite found in most plants, with appreciable…”
Get more information

Silymarin modulates doxorubicin-induced oxidative stress, Bcl-xL and p53 expression while preventing apoptotic and necrotic cell death in the liver by Patel, Nirav, Joseph, Cecil, Corcoran, George B., Ray, Sidhartha D.

“…The emergence of silymarin (SMN) as a natural remedy for liver diseases, coupled with its entry into NIH clinical trial, signifies its hepatoprotective…”
Get full text

Doxorubicin-induced in vivo nephrotoxicity involves oxidative stress-mediated multiple pro- and anti-apoptotic signaling pathways by Lahoti, Tejas S, Patel, Darshan, Thekkemadom, Venkatesh, Beckett, Robert, Ray, Sidhartha D

“…Doxorubicin (DOX), a prominent anticancer agent has enjoyed considerable popularity in the last few decades because of its usefulness in the management of…”
Get more information

Review of Published Bitter Orange Extract and p-Synephrine Adverse Event Clinical Study Case Reports by Stohs, Sidney J., Ray, Sidhartha D.

“…p-Synephrine is the primary active ingredient in bitter orange (Citrus aurantium) extract and is present in other citrus species. This review summarizes all…”
Get full text

Curcumin exposure modulates multiple pro-apoptotic and anti-apoptotic signaling pathways to antagonize acetaminophen-induced toxicity by Bulku, Elida, Stohs, Sidney J, Cicero, Lorraine, Brooks, Tracy, Halley, Herb, Ray, Sidhartha D

“…Curcumin (CUR; diferuloylmethane), a rhizome extract of Curcuma Longa L. is commonly used as a food coloring and flavoring agent. Although oriental and…”
Get more information

Curcumin, Hesperidin, and Rutin Selectively Interfere with Apoptosis Signaling and Attenuate Streptozotocin-Induced Oxidative Stress-Mediated Hyperglycemia by Parmar, Mayur S, Syed, Ismail, Gray, Joshua P, Ray, Sidhartha D

“…Type I Diabetes is characterized by the presence of hyperglycemia due to insulin deficiency and consequent impaired hepatic glucose metabolism. During…”
Get more information

Molecular mechanisms of cardioprotection by a novel grape seed proanthocyanidin extract by Bagchi, Debasis, Sen, Chandan K, Ray, Sidhartha D, Das, Dipak K, Bagchi, Manashi, Preuss, Harry G, Vinson, Joe A

“…Free radicals and oxidative stress play a crucial role in the pathophysiology of a broad spectrum of cardiovascular diseases including congestive heart…”
Get more information

Free radicals and grape seed proanthocyanidin extract: importance in human health and disease prevention by Bagchi, Debasis, Bagchi, Manashi, Stohs, Sidney J, Das, Dipak K, Ray, Sidhartha D, Kuszynski, Charles A, Joshi, Shantaram S, Pruess, Harry G

“…Free radicals have been implicated in over a hundred disease conditions in humans, including arthritis, hemorrhagic shock, atherosclerosis, advancing age,…”
Get full text

Oxidative Toxicity in Neurodegenerative Diseases: Role of Mitochondrial Dysfunction and Therapeutic Strategies by Facecchia, Katie, Fochesato, Lee-Anne, Ray, Sidhartha D., Stohs, Sidney J., Pandey, Siyaram

“…Besides fluorine, oxygen is the most electronegative element with the highest reduction potential in biological systems. Metabolic pathways in mammalian cells…”
Get full text

Hepatocellular carcinoma and microRNA: New perspectives on therapeutics and diagnostics by Yang, Ningning, Ekanem, Nsikak R., Sakyi, Clement A., Ray, Sidhartha D.

“…Hepatocellular carcinoma (HCC) remains one of the most lethal forms of cancer in the world. In this arena, utilities of microRNA (miRNA) as a sophisticated…”
Get full text

Matrix metalloproteinase-9, -10, and -12, MDM2 and p53 expression in mouse liver during dimethylnitrosamine-induced oxidative stress and genomic injury by Syed, Ismail, Rathod, Jasmine, Parmar, Mayur, Corcoran, George B., Ray, Sidhartha D.

“…Treatment during early tumor development has greater success because tissue growth remains largely confined to its original locus. At later stages, malignant…”
Get full text

A Review and Evaluation of the Efficacy and Safety of Cissus quadrangularis Extracts by Stohs, Sidney J., Ray, Sidhartha D.

“…Extracts and powders of Cissus quadrangularis have been used for many years to promote bone and tissues healing, as an analgesic, to treat infections, as an…”
Get full text

Proanthocyanidin exposure to B6C3F1 mice significantly attenuates dimethylnitrosamine-induced liver tumor induction and mortality by differentially modulating programmed and unprogrammed cell deaths by Ray, Sidhartha D, Parikh, Hemal, Bagchi, Debasis

“…Proanthocyanidins are of current interest as chemopreventive agents. The potential of the pre-, post- and co-exposure of proanthocyanidin-rich grape seed…”
Get more information

The Benefits Outweigh the Risks of Treating Hypercholesterolemia: The Statin Dilemma by Hussain, Azhar, Kaler, Jasndeep, Ray, Sidhartha D

“…Cardiovascular diseases are one of the leading causes of death in the United States; therefore, primary and secondary prevention are of the utmost importance…”
Get full text

Protective effects of the resveratrol analog piceid in dopaminergic SH-SY5Y cells by Potdar, Sneha, Parmar, Mayur S., Ray, Sidhartha D., Cavanaugh, Jane E.

“…Age-related motor deficits, such as loss of balance and coordination, are caused, in part, by loss of dopaminergic neurons. Oxidative stress is known to play a…”
Get full text

Enhancing Pharmacy Faculty Well-Being and Productivity While Reducing Burnout by Kennedy, Daniel R., Clapp, Peter, DeLuca, Judith L., Filtz, Theresa M., Kroon, Lisa, Lamberts, Jennifer T., Oliphant, Catherine M., Prescott, William Allan, Ray, Sidhartha D.

“…Objective. To explore methods that pharmacy programs can use to redefine their work environment to reduce stress, improve well-being, and increase faculty…”
Get full text

The fallacy of enzymatic hydrolysis for the determination of bioactive curcumin in plasma samples as an indication of bioavailability: a comparative study by Stohs, Sidney J, Chen, C Y O, Preuss, Harry G, Ray, Sidhartha D, Bucci, Luke R, Ji, Jin, Ruff, Kevin J

“…Numerous health benefits have been demonstrated for curcumin which is extracted from turmeric (Curcuma longa L). However, due to its poor absorption in the…”
Get full text

A novel dietary supplement containing multiple phytochemicals and vitamins elevates hepatorenal and cardiac antioxidant enzymes in the absence of significant serum chemistry and genomic changes by Bulku, Elida, Zinkovsky, Daniel, Patel, Payal, Javia, Vishal, Lahoti, Tejas, Khodos, Inna, Stohs, Sidney J, Ray, Sidhartha D

“…A novel dietary supplement composed of three well-known phytochemicals, namely, Salvia officinalis (sage) extract, Camellia sinensis (oolong tea) extract, and…”
Get full text