Search Results - "Ray, Manju"

Active mitochondrial respiration in cancer: a target for the drug by Bedi, Minakshi, Ray, Manju, Ghosh, Alok

“…The relative contribution of mitochondrial respiration and subsequent energy production in malignant cells has remained controversial to date. Enhanced aerobic…”
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Methylglyoxal in combination with 5-Fluorouracil elicits improved chemosensitivity in breast cancer through apoptosis and cell cycle inhibition by Ghosh, Sonali, Pal, Aparajita, Ray, Manju

“…[Display omitted] The anti-carcinogenic effect of Methylglyoxal (MG) is well established. It generally targets malignant cells by affecting glycolysis and…”
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A short review on creatine–creatine kinase system in relation to cancer and some experimental results on creatine as adjuvant in cancer therapy by Patra, Subrata, Ghosh, Alok, Roy, Soumya Sinha, Bera, Soumen, Das, Manju, Talukdar, Dipa, Ray, Subhankar, Wallimann, Theo, Ray, Manju

“…The creatine/creatine kinase (CK) system plays a key role in cellular energy buffering and transport. In vertebrates, CK has four isoforms expressed in a…”
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Progressive decrease of phosphocreatine, creatine and creatine kinase in skeletal muscle upon transformation to sarcoma by Patra, Subrata, Bera, Soumen, SinhaRoy, Soumya, Ghoshal, Sarani, Ray, Subhankar, Basu, Abhimanyu, Schlattner, Uwe, Wallimann, Theo, Ray, Manju

“…In vertebrates, phosphocreatine and ATP are continuously interconverted by the reversible reaction of creatine kinase in accordance with cellular energy needs…”
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Activation of macrophages and lymphocytes by methylglyoxal against tumor cells in the host by Bhattacharyya, Nivedita, Pal, Aparajita, Patra, Subrata, Haldar, Arun Kumar, Roy, Syamal, Ray, Manju

“…Methylglyoxal is a normal metabolite and has the potential to affect a wide variety of cellular processes. In particular, it can act selectively against…”
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Protective effect of creatine against inhibition by methylglyoxal of mitochondrial respiration of cardiac cells by Roy, Soumya Sinha, Biswas, Swati, Ray, Manju, Ray, Subhankar

“…Previous publications from our laboratory have shown that methylglyoxal inhibits mitochondrial respiration of malignant and cardiac cells, but it has no effect…”
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Selective inhibition of mitochondrial respiration and glycolysis in human leukaemic leucocytes by methylglyoxal by Biswas, S, Ray, M, Misra, S, Dutta, D P, Ray, S

“…The effect of methylglyoxal on the oxygen consumption of mitochondria of both normal and leukaemic leucocytes was tested by using different respiratory…”
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Further testing of antiviral activity of methylglyoxal urgently needed by Talukdar, Dipa, Ray, Subhankar, Ray, Manju

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In vivo assessment of toxicity and pharmacokinetics of methylglyoxal by Ghosh, Manju, Talukdar, Dipa, Ghosh, Swapna, Bhattacharyya, Nivedita, Ray, Manju, Ray, Subhankar

“…Previous in vivo studies from several laboratories had shown remarkable curative effect of methylglyoxal on cancer-bearing animals. In contrast, most of the…”
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Creatine supplementation with methylglyoxal: a potent therapy for cancer in experimental models by Pal, Aparajita, Roy, Anirban, Ray, Manju

“…The anti-cancer effect of methylglyoxal (MG) is now well established in the literature. The main aim of this study was to investigate the effect of creatine as…”
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Methylglyoxal at metronomic doses sensitizes breast cancer cells to doxorubicin and cisplatin causing synergistic induction of programmed cell death and inhibition of stemness by Roy, Anirban, Sarker, Sushmita, Upadhyay, Priyanka, Pal, Aparajita, Adhikary, Arghya, Jana, Kuladip, Ray, Manju

“…[Display omitted] Potent anticancer activity coupled with absence of toxicity at therapeutic dose established the glycolytic metabolite, methylglyoxal, as a…”
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Immunomodulation of macrophages by methylglyoxal conjugated with chitosan nanoparticles against Sarcoma-180 tumor in mice by Chakrabarti, Adrita, Talukdar, Dipa, Pal, Aparajita, Ray, Manju

“…•We developed a methylglyoxal chitosan conjugate called ‘Nano-MG’.•This compound has anticancer and immunomodulatory role.•Nano-MG reduced murine Sarcoma-180…”
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Inhibition of glycolysis and mitochondrial respiration of Ehrlich ascites carcinoma cells by methylglyoxal by Halder, J, Ray, M, Ray, S

“…The effect of methylglyoxal (MG) on the aerobic glycolysis of Ehrlich ascites carcinoma (EAC) cells has been tested. Methylglyoxal inhibited glucose…”
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Induction of mitochondrial apoptotic pathway in triple negative breast carcinoma cells by methylglyoxal via generation of reactive oxygen species by Roy, Anirban, Ahir, Manisha, Bhattacharya, Saurav, Parida, Pravat Kumar, Adhikary, Arghya, Jana, Kuladip, Ray, Manju

“…Triple negative breast cancer (TNBC) tends to form aggressive tumors associated with high mortality and morbidity which urge the need for development of new…”
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Nanofabrication of methylglyoxal with chitosan biopolymer: a potential tool for enhancement of its anticancer effect by Pal, Aparajita, Talukdar, Dipa, Roy, Anirban, Ray, Subhankar, Mallick, Asish, Mandal, Chitra, Ray, Manju

“…The normal metabolite methylglyoxal (MG) specifically kills cancer cells by inhibiting glycolysis and mitochondrial respiration without much adverse effect…”
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Mechanistic studies on the binding of Acid Yellow 99 on coir pith by Khan, Md. Motiar R., Ray, Manju, Guha, Arun K.

“…The interaction of Acid Yellow 99 (AY 99) with coir pith has been investigated in aqueous medium to understand the mechanism of adsorption and explore the…”
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Quercetin interferes with iron metabolism in Leishmania donovani and targets ribonucleotide reductase to exert leishmanicidal activity by Sen, Gargi, Mukhopadhyay, Sibabrata, Ray, Manju, Biswas, Tuli

“…Objectives The possibility of developing antileishmanial drugs was evaluated by intervention in the parasite's iron metabolism, utilizing quercetin (Qr) under…”
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Modulation of glyceraldehyde-3-phosphate dehydrogenase activity by surface functionalized quantum dots by Ghosh, Srabanti, Ray, Manju, Das, Mahua Rani, Chakrabarti, Adrita, Khan, Ali Hossain, Sarma, D D, Acharya, Somobrata

“…Enzymatic regulation is a fast and reliable diagnosis tool via identification and design of inhibitors for modulation of enzyme function. Previous reports on…”
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Enzymes of creatine biosynthesis, arginine and methionine metabolism in normal and malignant cells by Bera, Soumen, Wallimann, Theo, Ray, Subhankar, Ray, Manju

“…The creatine/creatine kinase system decreases drastically in sarcoma. In the present study, an investigation of catalytic activities, western blot and mRNA…”
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Molecular association of glucose-6-phosphate isomerase and pyruvate kinase M2 with glyceraldehyde-3-phosphate dehydrogenase in cancer cells by Das, Mahua R, Bag, Arup K, Saha, Shekhar, Ghosh, Alok, Dey, Sumit K, Das, Provas, Mandal, Chitra, Ray, Subhankar, Chakrabarti, Saikat, Ray, Manju, Jana, Siddhartha S

“…For a long time cancer cells are known for increased uptake of glucose and its metabolization through glycolysis. Glyceraldehyde-3-phosphate dehydrogenase…”
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