Search Results - "Rawlinson, S.C.F."

Interactions of strontium with the dentine-pulp complex by Huang, M, Rawlinson, S.C.F, Hill, R.G

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Mechanical strain and fluid movement both activate extracellular regulated kinase (ERK) in osteoblast-like cells but via different signaling pathways by Jessop, H.L, Rawlinson, S.C.F, Pitsillides, A.A, Lanyon, L.E

“…Extracellular regulated kinases (ERKs)-1 and -2 are members of the MAPK family of protein kinases involved in the proliferation, differentiation, and apoptosis…”
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Changes in Bone Mineral and Matrix in Response to a Soft Diet by Kingsmill, V.J., Boyde, A., Davis, G.R., Howell, P.G.T., Rawlinson, S.C.F.

“…Alterations in the magnitude of habitual mechanical loads upon the skeleton may not only affect bone architecture, but also influence the nature of the bone…”
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POST-MENOPAUSAL OSTEOPOROSIS-RESISTANT SKULL BONES – GENOTYPICALLY DISTINCT FROM OSTEOPOROTIC-SUSCEPTIBLE LIMB BONE by Rawlinson, S.C.F, McKay, I.J, Ghuman, M, Wellmann, C, Hughes, F.J, Kingsmill, V.J

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Ovariectomy vs. Hypofunction: Their Effects on Rat Mandibular Bone by Rawlinson, S.C.F., Boyde, A., Davis, G.R., Howell, P.G.T., Hughes, F.J., Kingsmill, V.J.

“…Previous studies have suggested that the mandible may be more influenced by mechanical loading than by circulating hormone levels. We tested the hypothesis…”
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Genetic selection for fast growth generates bone architecture characterised by enhanced periosteal expansion and limited consolidation of the cortices but a diminution in the early responses to mechanical loading by Rawlinson, Simon C.F, Murray, Dianne H, Mosley, John R, Wright, Chris D.P, Bredl, John C, Saxon, Leanne K, Loveridge, Nigel, Leterrier, Christine, Constantin, Paul, Farquharson, Colin, Pitsillides, Andrew A

“…Abstract Bone strength is, in part, dependent on a mechanical input that regulates the (re)modelling of skeletal elements to an appropriate size and…”
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Arachidonic acid for loading induced prostacyclin and prostaglandin E 2 release from osteoblasts and osteocytes is derived from the activities of different forms of phospholipase A 2 by Rawlinson, S.C.F, Wheeler-Jones, C.P.D, Lanyon, L.E

“…Mechanical loading of bone stimulates resident bone cells to produce prostacyclin (PGI 2) and prostaglandin (PG)E 2 by a mechanism that can be differentially…”
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Arachidonic acid for loading induced prostacyclin and prostaglandin E2 release from osteoblasts and osteocytes is derived from the activities of different forms of phospholipase A2 by RAWLINSON, S. C. F, WHEELER-JONES, C. P. D, LANYON, L. E

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Involvement of different ion channels in osteoblasts' and osteocytes' early responses to mechanical strain by Rawlinson, S.C.F., Pitsillides, A.A., Lanyon, L.E.

“…The involvement of functional ion channels in previously documented early responses of osteocytes and osteoblasts to mechanical strain in bone tissue was…”
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P10. Early responses to mechanical load in selectively-bred embryonic chicks differ by Pitsillides, A.A., Rawlinson, S.C.F., Lanyon, L.E.

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The prostacyclin synthetase inhibitor, 15-HPETE, blocks strain-related increases in osteocytic G6PD activity and reduces nitric oxide release by Rawlinson, S.C.F., Mtsillides, A.A., Lanyon, L.E.

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Strain measurement by bone cells during mechanical loading by Rawlinson, S.C.F., Pitsillides, A.A., Lanyon, L.E.

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Nitric oxide production is stimulated by mechanical loading by Pitsillides, A.A., Rawlinson, S.C.F., Suswillo, R.F.L., Lanyon, L.E.

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Heme oxygenase isozymes in bone: induction of HO-1 mRNA following physiological levels of mechanical loading in vivo by Rawlinson, S.C.F., Zaman, G., Mosley, J.R., Pitsillides, A.A., Lanyon, L.E.

“…Heme oxygenases (HO) are responsible for the production of carbon monoxide, which has been suggested to act similarly to nitric oxide as a signaling molecule…”
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Mechanical strain enhances no production and upregulates nNOS mRNA levels by Zaman, G., Rawlinson, S.C.F., Pitsillides, A.A., Price, J.S., Suswillo, R.F.L., Cheng, M.Z., Lanyon, L.E.

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