Search Results - "Rawda M. Okasha"

Successful Green Synthesis of Gold Nanoparticles using a Corchorus olitorius Extract and Their Antiproliferative Effect in Cancer Cells by Ismail, Eman H, Saqer, Aliyah M A, Assirey, Eman, Naqvi, Arshi, Okasha, Rawda M

“…A facile bottom-up "green" synthetic route of gold nanoparticles (Au NPs) is described, using a leaf extract of the plant as a reducing and stabilizing agent…”
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A New Family of Benzo[ h ]Chromene Based Azo Dye: Synthesis, In-Silico and DFT Studies with In Vitro Antimicrobial and Antiproliferative Assessment by Abd-El-Aziz, Alaa S, Alsaggaf, Azhaar, Assirey, Eman, Naqvi, Arshi, Okasha, Rawda M, Afifi, Tarek H, Hagar, Mohamed

“…The high biological activity of the chromene compounds coupled with the intriguing optical features of azo chromophores prompted our desire to construct novel…”
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Synthesis and Characterization of a New Class of Chromene-Azo Sulfonamide Hybrids as Promising Anticancer Candidates with the Exploration of Their EGFR, hCAII, and MMP-2 Inhibitors Based on Molecular Docking Assays by Alblewi, Fawzia F., Alsehli, Mosa H., Hritani, Zainab M., Eskandrani, Areej, Alsaedi, Wael H., Alawad, Majed O., Elhenawy, Ahmed A., Ahmed, Hanaa Y., El-Gaby, Mohamed S. A., Afifi, Tarek H., Okasha, Rawda M.

“…In this study, novel selective antitumor compounds were synthesized based on their fundamental pharmacophoric prerequisites associated with EGFR inhibitors. A…”
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DFT and In-silico Investigations, along with In-vitro Antitumor and Antimicrobial Assessments of Pharmacological Molecules by Alsehli, Mosa H, Seth, Daya S, El-Gaby, Mohamed S A, Okasha, Rawda M, Hagar, Mohamed, Afifi, Tarek H, Naqvi, Arshi

“…Molecules bearing an active methylene bridge are one of the most fruitful and remarkable precursors that have been incorporated into the synthetic strategy of…”
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Discovery of benzochromene derivatives first example with dual cytotoxic activity against the resistant cancer cell MCF-7/ADR and inhibitory effect of the P-glycoprotein expression levels by Al-Harbi, Laila M., Al-Harbi, Eman A., Okasha, Rawda M., El-Eisawy, R. A., El-Nassag, Mohammed A. A., Mohamed, Hany M., Fouda, Ahmed M., Elhenawy, Ahmed A., Mora, Ahmed, El-Agrody, Ahmed M., El-Mawgoud, Heba K. A.

“…A series of 1H-benzo[f]chromene moieties (4a-z) were synthesised under Ultrasonic irradiation and confirmed with spectral analyses. Derivative 4i solely…”
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Synthesis, Biological Assessment, and Structure Activity Relationship Studies of New Flavanones Embodying Chromene Moieties by Assirey, Eman, Alsaggaf, Azhaar, Naqvi, Arshi, Moussa, Ziad, Okasha, Rawda M, Afifi, Tarek H, Abd-El-Aziz, Alaa S

“…Novel flavanones that incorporate chromene motifs are synthesized via a one-step multicomponent reaction. The structures of the new chromenes are elucidated by…”
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Design of New Benzo[h]chromene Derivatives: Antitumor Activities and Structure-Activity Relationships of the 2,3-Positions and Fused Rings at the 2,3-Positions by Okasha, Rawda M, Alblewi, Fawzia F, Afifi, Tarek H, Naqvi, Arshi, Fouda, Ahmed M, Al-Dies, Al-Anood M, El-Agrody, Ahmed M

“…A series of novel 4 -benzo[ ]chromenes , - , , ; 7 -benzo[ ]chromeno[2,3- ]pyrimidines - , , and 14 -benzo[ ]chromeno[3,2- ][1,2,4]triazolo[1,5- ]pyrimidine…”
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Design and Synthesis of Novel Heterocyclic-Based 4H-benzo[h]chromene Moieties: Targeting Antitumor Caspase 3/7 Activities and Cell Cycle Analysis by Alblewi, Fawzia, Okasha, Rawda, Eskandrani, Areej, Afifi, Tarek, Mohamed, Hany, Halawa, Ahmed, Fouda, Ahmed, Al-Dies, Al-Anood, Mora, Ahmed, El-Agrody, Ahmed

“…Novel fused chromenes (4,7–11) and pyrimidines (12–16) were designed, synthesized, and evaluated for their mammary gland breast cancer (MCF-7), human colon…”
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Design of Novel Oligomeric Mixed Ligand Complexes: Preparation, Biological Applications and the First Example of Their Nanosized Scale by Okasha, Rawda M, Al-Shaikh, Najla E, Aljohani, Faizah S, Naqvi, Arshi, Ismail, Eman H

“…A successful oligomerization of ternary metal complexes, cobalt (II), nickel (II), copper (II), zinc (II), chromium (III) and ferric sulfate (III) with…”
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Introducing novel potent anticancer agents of 1H-benzo[f]chromene scaffolds, targeting c-Src kinase enzyme with MDA-MB-231 cell line anti-invasion effect by Ahmed, Hany E. A., El-Nassag, Mohammed A. A., Hassan, Ahmed H., Okasha, Rawda M., Ihmaid, Saleh, Fouda, Ahmed M., Afifi, Tarek H., Aljuhani, Ateyatallah, El-Agrody, Ahmed M.

“…In our effort to develop novel and powerful agents with anti-proliferative activity, two new series of 1H-benzo[f]chromene derivatives, 4a-h and 6a-h, were…”
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Structural Characterization and Antimicrobial Activities of 7H-Benzo[h]chromeno[2,3-d]pyrimidine and 14H-Benzo[h]chromeno[3,2-e][1,2,4]triazolo[1,5-c] pyrimidine Derivatives by Okasha, Rawda M, Albalawi, Fawzia F, Afifi, Tarek H, Fouda, Ahmed M, Al-Dies, Al-Anood M, El-Agrody, Ahmed M

“…Three new series of chromene molecules have been synthesized in order to explore their antimicrobial activity. The series encompass 2-substituted…”
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Cationic Cyclopentadienyliron Complex as a Novel and Successful Nucleating Agent on the Crystallization Behavior of the Biodegradable PHB Polymer by El-Taweel, Safaa H, Al-Ahmadi, Arwa O, Alhaddad, Omaima, Okasha, Rawda M

“…Cationic cyclopentadienyliron (CpFe⁺) is one of the most fruitful organometallic moieties that has been utilized to mediate the facile synthesis of a massive…”
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Rational Design and Synthesis of Diverse Pyrimidine Molecules Bearing Sulfonamide Moiety as Novel ERK Inhibitors by Halawa, Ahmed H, Eskandrani, Areej A, Elgammal, Walid E, Hassan, Saber M, Hassan, Ahmed H, Ebrahim, Hassan Y, Mehany, Ahmed B M, El-Agrody, Ahmed M, Okasha, Rawda M

“…Protein kinases orchestrate diverse cellular functions; however, their dysregulation is linked to metabolic dysfunctions, associated with many diseases,…”
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Novel 2-Hydroselenonicotinonitriles and Selenopheno[2, 3-b]pyridines: Efficient Synthesis, Molecular Docking-DFT Modeling, and Antimicrobial Assessment by Abdellattif, Magda H., Abdel-Rahman, Adel A. H., Arief, Mohamed Mohamed Helmy, Mouneir, Samar M., Ali, Amena, Hussien, Mostafa A., Okasha, Rawda M., Afifi, Tarek H., Hagar, Mohamed

“…Selenium containing heterocyclic compounds gained great interest as bioactive molecules as of late. This report explores the design, synthesis,…”
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Synthesis, Cytotoxic Activity, Crystal Structure, DFT, Molecular Docking Study of β-Enaminonitrile Incorporating 1H-Benzo[f]Chromene Moiety by Alsehli, Mosa H., Al-Harbi, Lali M., Okasha, Rawda M., Fouda, Ahmed M., Ghabbour, Hazem A., Amr, Abd El-Galil E., Elhenawy, Ahmed A., El-Agrody, Ahmed M.

“…In this work, we used microwave irradiation conditions to synthesize β-enaminonitrile (4), which was affirmed using single crystal X-ray diffraction and the…”
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The Crystal Structure of 3-Amino-1-(4-Chlorophenyl)-9-Methoxy-1H-Benzo[f]Chromene-2-Carbonitrile: Antimicrobial Activity and Docking Studies by Okasha, Rawda M., Fouda, Ahmed M., Bajaber, Majed A., Ghabbour, Hazem A., E. Amr, Abd El-Galil, Naglah, Ahmed M., Almehizia, Abdulrahman A., Elhenawy, Ahmed A., El-Agrody, Ahmed M.

“…Compound 3-amino-1-(4-chlorophenyl)-9-methoxy-1H-benzo[f]chromene-2-carbonitrile (4), was synthesized via the reaction of 7-methoxynaphthalen-2-ol (1),…”
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The Crystal Structure of 2-Amino-4-(2,3-Dichlorophenyl)-6-Methoxy-4H-Benzo[h]chromene-3-Carbonitrile: Antitumor and Tyrosine Kinase Receptor Inhibition Mechanism Studies by El-Agrody, Ahmed M., Fouda, Ahmed M., Mohamed, Hany M., Alshahrani, Mohammed Y., Ghabbour, Hazem A., Amr, Abd El-Galil E., Okasha, Rawda M., Naglah, Ahmed M., Almehizia, Abdulrahman A., Elhenawy, Ahmed A.

“…The target compound, 2-amino-4-(2,3-dichlorophenyl)-6-methoxy-4H-benzo[h]chromene -3-carbonitrile (4), was synthesized via the reaction of…”
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Catalytic Activity of Sulfated and Phosphated Catalysts towards the Synthesis of Substituted Coumarin by Nagi R. E. Radwan, Mohamed Hagar, Tarek H. Afifi, Fahd Al-wadaani, Rawda M. Okasha

“…New modified acidic catalysts were prepared from the treatment of silica, titania and silica prepared from hydrolyzed tetraethyl orthosilicate (TEOS) with…”
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Design of Thermochromic Polynorbornene Bearing Spiropyran Chromophore Moieties: Synthesis, Thermal Behavior and Dielectric Barrier Discharge Plasma Treatment by Ahmed, Saleh A, Okasha, Rawda M, Khairou, Khalid S, Afifi, Tarek H, Mohamed, Abdel-Aleam H, Abd-El-Aziz, Alaa S

“…A new class of thermochromic polynorbornene with pendent spiropyran moieties has been synthesized. Functionalization of norbornene monomers with…”
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Effect of dopant on the conductivity and stability of three different cotton fabrics impregnated with PEDOT:PSS by Alhashmi Alamer, Fahad, Badawi, Nujud M., Alodhayb, Abdullah, Okasha, Rawda M., Kattan, Nessrin A.

“…This study has investigated the electrical conductivity (sheet resistance) and morphological properties of dental cotton, textile cotton and gauze cotton after…”
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