Search Results - "Rawat, P.S"

Concise Review: The Piwi-piRNA Axis: Pivotal Beyond Transposon Silencing by Bamezai, Shiva, Rawat, Vijay P.S., Buske, Christian

“…Piwi proteins and their associated piRNAs are essential for preserving the self‐renewal property of mammalian germ stem cells. Their highly conserved role in…”
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TET Genes: new players in DNA demethylation and important determinants for stemness by Mohr, Fabian, Döhner, Konstanze, Buske, Christian, Rawat, Vijay P.S

“…Stem cells are defined as cells that have the ability to perpetuate themselves through self-renewal and to generate functional mature cells by differentiation…”
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MEIS2 Is an Oncogenic Partner in AML1-ETO-Positive AML by Vegi, Naidu M., Klappacher, Josef, Oswald, Franz, Mulaw, Medhanie A., Mandoli, Amit, Thiel, Verena N., Bamezai, Shiva, Feder, Kristin, Martens, Joost H.A., Rawat, Vijay P.S., Mandal, Tamoghna, Quintanilla-Martinez, Leticia, Spiekermann, Karsten, Hiddemann, Wolfgang, Döhner, Konstanze, Döhner, Hartmut, Stunnenberg, Hendrik G., Feuring-Buske, Michaela, Buske, Christian

“…Homeobox genes are known to be key factors in leukemogenesis. Although the TALE family homeodomain factor Meis1 has been linked to malignancy, a role for MEIS2…”
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A novel role for Lef-1, a central transcription mediator of Wnt signaling, in leukemogenesis by Petropoulos, Konstantin, Arseni, Natalia, Schessl, Christina, Stadler, Christiane R, Rawat, Vijay P S, Deshpande, Aniruddha J, Heilmeier, Bernhard, Hiddemann, Wolfgang, Quintanilla-Martinez, Leticia, Bohlander, Stefan K, Feuring-Buske, Michaela, Buske, Christian

“…Canonical Wnt signaling is critically involved in normal hematopoietic development and the self-renewal process of hematopoietic stem cells (HSCs)…”
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The AML1-ETO fusion gene and the FLT3 length mutation collaborate in inducing acute leukemia in mice by Schessl, Christina, Rawat, Vijay P S, Cusan, Monica, Deshpande, Aniruddha, Kohl, Tobias M, Rosten, Patricia M, Spiekermann, Karsten, Humphries, R Keith, Schnittger, Susanne, Kern, Wolfgang, Hiddemann, Wolfgang, Quintanilla-Martinez, Leticia, Bohlander, Stefan K, Feuring-Buske, Michaela, Buske, Christian

“…The molecular characterization of leukemia has demonstrated that genetic alterations in the leukemic clone frequently fall into 2 classes, those affecting…”
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The ParaHox gene Cdx4 induces acute erythroid leukemia in mice by Thoene, Silvia, Mandal, Tamoghna, Vegi, Naidu M., Quintanilla-Martinez, Leticia, Rösler, Reinhild, Wiese, Sebastian, Metzeler, Klaus H., Herold, Tobias, Haferlach, Torsten, Döhner, Konstanze, Döhner, Hartmut, Schwarzmüller, Luisa, Klingmüller, Ursula, Buske, Christian, Rawat, Vijay P.S., Feuring-Buske, Michaela

“…Acute erythroid leukemia (AEL) is a rare and aggressive form of acute leukemia, the biology of which remains poorly understood. Here we demonstrate that the…”
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Micro-level adaptation strategies by smallholders to adapt climate change in the least developed countries (LDCs): Insights from Afghanistan by Omerkhil, Najibullah, Kumar, Praveen, Mallick, Manisha, Meru, Lungyina B., Chand, Tara, Rawat, P.S., Pandey, Rajiv

“…•Climate adaptations by small-holders in Afghanistan are governed by household characteristics.•Assets, profession and male population determine the adoption…”
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vent-like homeobox gene VENTX promotes human myeloid differentiation and is highly expressed in acute myeloid leukemia by Rawat, Vijay P.S, Arseni, Natalia, Ahmed, Farid, Mulaw, Medhanie A, Thoene, Silvia, Heilmeier, Bernhard, Sadlon, Tim, D'Andrea, Richard J, Hiddemann, Wolfgang, Bohlander, Stefan K, Buske, Christian, Feuring-Buske, Michaela

“…Recent data indicate that a variety of regulatory molecules active in embryonic development may also play a role in the regulation of early hematopoiesis. Here…”
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Electronic and Cooper pair tunneling signatures in the electronic spectra of superconductors coupled to quantum dot nano-junction by Dhyani, A., Mandal, P., Rawat, P.S., Tewari, B.S.

“…•This paper deals with charge (electronic only) transfer across nanoscopic (Josephson) junctions.•Numerical calculations for spectral function for…”
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Nuclear Structure and Decay Data for A = 222 Isobars by Balraj, Singh, Basunia, M.S., Jun, Chen, Dimitriou, P., Amro, B.M.S., Basu, S., Das, S., Diwanshu, Karmakar, A., Lazaric, M.J., Leblond, S.R., Nayak, S.S., Ngwetsheni, C., Rathi, A., Rawat, P.S., Rohila, B., Vallet, V.

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Spectral density of Cooper pairs in two level quantum dot–superconductors Josephson junction by Dhyani, A., Rawat, P.S., Tewari, B.S.

“…•The present work deals with the study of the electronic spectral density of electron pairs and its effect in charge transport in superconductor-quantum…”
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Seed source variation in morphology, germination and seedling growth of Jatropha curcas Linn. in Central India. [Erratum: 2006, v. 55, no. 2, p. 92.] by Ginwal, H.S, Phartyal, S.S, Rawat, P.S, Srivastava, R.L

“…The aim of the study was to determine source variation in Jatropha curcas seeds collected from ten locations in Central India. A significant seed source…”
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TET3 promotes AML growth and epigenetically regulates glucose metabolism and leukemic stem cell associated pathways by Pulikkottil, Alex Jose, Bamezai, Shiva, Ammer, Tobias, Mohr, Fabian, Feder, Kristin, Vegi, Naidu M., Mandal, Tamoghna, Kohlhofer, Ursula, Quintanilla-Martinez, Leticia, Sinha, Amit, Buske, Christian, Rawat, Vijay P. S.

“…Acute myeloid leukemia (AML) is considered a poor prognosis malignancy where patients exhibit altered glucose metabolism and stem cell signatures that…”
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Seed source variation in growth performance and oil yield of Jatropha curcas Linn. in central India. [Erratum: 2006, v. 55, no. 2, p. 92.] by Ginwal, H.S, Rawat, P.S, Srivastava, R.L

“…Results of a seed source evaluation trial of Jatropha curcas Linn. laid out in 1996 at Jabalpur (M.P), a semi arid region of India are reported and discussed…”
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TET1 promotes growth of T-cell acute lymphoblastic leukemia and can be antagonized via PARP inhibition by Bamezai, Shiva, Demir, Deniz, Pulikkottil, Alex Jose, Ciccarone, Fabio, Fischbein, Elena, Sinha, Amit, Borga, Chiara, te Kronnie, Geertruy, Meyer, Lüder-Hinrich, Mohr, Fabian, Götze, Maria, Caiafa, Paola, Debatin, Klaus-Michael, Döhner, Konstanze, Döhner, Hartmut, González-Menéndez, Irene, Quintanilla-Fend, Leticia, Herold, Tobias, Jeremias, Irmela, Feuring-Buske, Michaela, Buske, Christian, Rawat, Vijay P. S.

“…T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological cancer characterized by skewed epigenetic patterns, raising the possibility of…”
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Differences in expression and function of LEF1 isoforms in normal versus leukemic hematopoiesis by Feder, Kristin, Edmaier-Schröger, Katrin, Rawat, Vijay P. S., Kirsten, Nicole, Metzeler, Klaus, Kraus, Johann M., Döhner, Konstanze, Döhner, Hartmut, Kestler, Hans A., Feuring-Buske, Michaela, Buske, Christian

“…Acute myeloid leukemia (AML) is the most common acute leukemia in adults and is propagated by leukemic stem cells (LSCs), often characterized by deregulated…”
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A noncanonical enzymatic function of PIWIL4 maintains genomic integrity and leukemic growth in AML by Bamezai, Shiva, Pulikkottil, Alex Jose, Yadav, Tribhuwan, Vegi, Naidu M., Mueller, Julia, Mark, Jasmin, Mandal, Tamoghna, Feder, Kristin, Ihme, Susann, Song, Chenlin, Rosler, Reinhild, Wiese, Sebastian, Hoell, Jessica I., Kloetgen, Andreas, Karsan, Aly, Kumari, Ankita, Wojenski, Luke, Sinha, Amit U., Gonzalez-Menendez, Irene, Quintanilla-Martinez, Leticia, Donato, Elisa, Trumpp, Andreas, Kruse, Elisabeth, Hamperl, Stephan, Zou, Lee, Rawat, Vijay P. S., Buske, Christian

“…•The RNase H–like superfamily member PIWIL4 is required for leukemic stem cell function but dispensable for human hematopoietic stem cells.•PIWIL4 prevents…”
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Targeting of CXCR4 by the Naturally Occurring CXCR4 Antagonist EPI-X4 in Waldenström's Macroglobulinemia by Kaiser, Lisa Marie, Harms, Mirja, Sauter, Daniel, Rawat, Vijay P S, Glitscher, Mirco, Hildt, Eberhard, Tews, Daniel, Hunter, Zachary, Münch, Jan, Buske, Christian

“…CXCR4 expression and downstream signaling have been identified as key factors in malignant hematopoiesis. Thus, up to 40% of all patients with Waldenström's…”
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Somatostatin receptor mediated targeting of acute myeloid leukemia by photodynamic metal complexes for light induced apoptosis by Vegi, Naidu M., Chakrabortty, Sabyasachi, Zegota, Maksymilian M., Kuan, Seah Ling, Stumper, Anne, Rawat, Vijay P. S., Sieste, Stefanie, Buske, Christian, Rau, Sven, Weil, Tanja, Feuring-Buske, Michaela

“…Acute myeloid leukemia (AML) is characterized by relapse and treatment resistance in a major fraction of patients, underlining the need of innovative AML…”
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The microRNA miR-196b acts as a tumor suppressor in Cdx2-driven acute myeloid leukemia by Rawat, Vijay P S, Götze, Maria, Rasalkar, Avinash, Vegi, Naidu M, Ihme, Susann, Thoene, Silvia, Pastore, Alessandro, Bararia, Deepak, Döhner, Hartmut, Döhner, Konstanze, Feuring-Buske, Michaela, Quintanilla-Fend, Leticia, Buske, Christian

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