Search Results - "Ravishankar, Shashidhar"

Mapping-free variant calling using haplotype reconstruction from k-mer frequencies by Audano, Peter A, Ravishankar, Shashidhar, Vannberg, Fredrik O

“…Abstract Motivation The standard protocol for detecting variation in DNA is to map millions of short sequence reads to a known reference and find loci that…”
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Class II HLA-DRB4 is a predictive biomarker for survival following immunotherapy in metastatic non-small cell lung cancer by Jiang, Cindy Y., Zhao, Lili, Green, Michael D., Ravishankar, Shashidhar, Towlerton, Andrea M. H., Scott, Anthony J., Raghavan, Malini, Cusick, Matthew F., Warren, Edus H., Ramnath, Nithya

“…Immune checkpoint inhibitors (ICI) are important treatment options for metastatic non-small cell lung cancer (mNSCLC). However, not all patients benefit from…”
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The first complete genome of the simian malaria parasite Plasmodium brasilianum by Bajic, Marko, Ravishankar, Shashidhar, Sheth, Mili, Rowe, Lori A., Pacheco, M. Andreina, Patel, Dhruviben S., Batra, Dhwani, Loparev, Vladimir, Olsen, Christian, Escalante, Ananias A., Vannberg, Fredrik, Udhayakumar, Venkatachalam, Barnwell, John W., Talundzic, Eldin

“…Naturally occurring human infections by zoonotic Plasmodium species have been documented for P. knowlesi , P. cynomolgi , P. simium , P. simiovale , P. inui ,…”
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Serial Analysis of the T-Cell Receptor β-Chain Repertoire in People Living With HIV Reveals Incomplete Recovery After Long-Term Antiretroviral Therapy by Towlerton, Andrea M H, Ravishankar, Shashidhar, Coffey, David G, Puronen, Camille E, Warren, Edus H

“…Long-term antiretroviral therapy (ART) in people living with HIV (PLHIV) is associated with sustained increases in CD4 T-cell count, but its effect on the…”
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Targeted deep amplicon sequencing of antimalarial resistance markers in Plasmodium falciparum isolates from Cameroon by L’Episcopia, Mariangela, Kelley, Julia, Djeunang Dongho, Bruna G., Patel, Dhruviben, Schmedes, Sarah, Ravishankar, Shashidhar, Perrotti, Edvige, Modiano, David, Lucchi, Naomi W., Russo, Gianluca, Talundzic, Eldin, Severini, Carlo

“…[Display omitted] •Artemisinin-based combination therapy for the treatment of malaria cases in Cameroon.•Drug resistance remains one of the greatest challenges…”
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XomAnnotate: Analysis of Heterogeneous and Complex Exome- A Step towards Translational Medicine by Talukder, Asoke K, Ravishankar, Shashidhar, Sasmal, Krittika, Gandham, Santhosh, Prabhukumar, Jyothsna, Achutharao, Prahalad H, Barh, Debmalya, Blasi, Francesco

“…In translational cancer medicine, implicated pathways and the relevant master genes are of focus. Exome's specificity, processing-time, and cost advantage…”
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First Full Draft Genome Sequence of Plasmodium brasilianum by Talundzic, Eldin, Ravishankar, Shashidhar, Nayak, Vishal, Patel, Dhruviben S, Olsen, Christian, Sheth, Mili, Batra, Dhwani, Loparev, Vladimir, Vannberg, Fredrik O, Udhayakumar, Venkatachalam, Barnwell, John W

“…is a protozoan parasite that can cause human malaria. The simian parasite infects New World monkeys from Latin America and is morphologically indistinguishable…”
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RNA helicase, DDX3X, is actively recruited to sites of DNA damage in live cells by Cargill, Michael J., Morales, Alicia, Ravishankar, Shashidhar, Warren, Edus H.

“…Recent studies have suggested that human RNA helicase, DDX3X, is important for DNA repair, but little is known about the nuclear activity of this protein. In…”
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Role of HLA-DRB4 as a biomarker for endocrine toxicity and survival outcomes after immunotherapy in metastatic non-small cell lung cancer by Jiang, Cindy, Ravishankar, Shashidhar, Zhao, Lili, Green, Michael, Towlerton, Andrea, Scott, Anthony, Raghavan, Malini, Cusick, Matthew, Warren, Edus H., Ramnath, Nithya

“…e21005 Background: Immune checkpoint inhibitors (ICI) have significantly improved outcomes in non-small cell lung cancer (NSCLC) but are associated with…”
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Next-Generation Sequencing and Bioinformatics Protocol for Malaria Drug Resistance Marker Surveillance by Talundzic, Eldin, Ravishankar, Shashidhar, Kelley, Julia, Patel, Dhruviben, Plucinski, Mateusz, Schmedes, Sarah, Ljolje, Dragan, Clemons, Brooke, Madison-Antenucci, Susan, Arguin, Paul M, Lucchi, Naomi W, Vannberg, Fredrik, Udhayakumar, Venkatachalam

“…The recent advances in next-generation sequencing technologies provide a new and effective way of tracking malaria drug-resistant parasites. To take advantage…”
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Evolution and Genetic Diversity of the k13 Gene Associated with Artemisinin Delayed Parasite Clearance in Plasmodium falciparum by Pacheco, M Andreína, Kadakia, Esha R, Chaudhary, Zainab, Perkins, Douglas J, Kelley, Julia, Ravishankar, Shashidhar, Cranfield, Michael, Talundzic, Eldin, Udhayakumar, Venkatachalam, Escalante, Ananias A

“…Mutations in the ( ) gene are linked to delayed parasite clearance in response to artemisinin-based combination therapies (ACTs) in Southeast Asia. To explore…”
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TLR-exosomes exhibit distinct kinetics and effector function by Srinivasan, Swetha, Su, Michelle, Ravishankar, Shashidhar, Moore, James, Head, PamelaSara, Dixon, J. Brandon, Vannberg, Fredrik

“…The innate immune system is vital to rapidly responding to pathogens and Toll-like receptors (TLRs) are a critical component of this response. Nanovesicular…”
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Geographic EBV variants confound disease-specific variant interpretation and predict variable immune therapy responses by Briercheck, Edward L., Ravishankar, Shashidhar, Ahmed, Elshafa Hassan, Carías Alvarado, César Camilo, Barrios Menéndez, Juan Carlos, Silva, Oscar, Solórzano-Ortiz, Elizabeth, Siliézar Tala, Marcos Mauricio, Stevenson, Philip, Xu, Yuexin, Wohns, Anthony Wilder, Enriquez-Vera, Daniel, Barrionuevo, Carlos, Yu, Shan-Chi, Freud, Aharon G., Oakes, Christopher, Weigel, Christoph, Weinstock, David M., Klimaszewski, Haley L., Ngankeu, Apollinaire, Mutalima, Nora, Samayoa-Reyes, Gabriela, Newton, Robert, Rochford, Rosemary, Valvert, Fabiola, Natkunam, Yasodha, Shustov, Andrei, Baiocchi, Robert A., Warren, Edus H.

“…•Geography, rather than disease, has a greater influence on genome-wide EBV variation.•Variation in EBV genomes predicts altered viral peptide binding to major…”
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TLR-exosomes exhibit distinct kinetics and effector function by Srinivasan, Swetha, Su, Michelle, Ravishankar, Shashidhar, Moore, James, Head, PamelaSara E, Dixon, J. Brandon, Vannberg, Fredrik O

“…The innate immune system is vital to rapidly responding to pathogens and Toll-like receptors (TLRs) are a critical component of this response. Nanovesicular…”
Get full text