Search Results - "Ravingerová, T"

Protection against ischemia-induced ventricular arrhythmias and myocardial dysfunction conferred by preconditioning in the rat heart: involvement of mitochondrial KATP channels and reactive oxygen species by Matejíková, J, Kucharská, J, Pintérová, M, Pancza, D, Ravingerová, T

“…Ischemic preconditioning (I-PC) induced by brief episodes of ischemia and reperfusion (I/R) protects the heart against sustained I/R. Although activation of…”
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The effect of chronic doxorubicin treatment on mitogen-activated protein kinases and heat stress proteins in rat hearts by Simoncíková, P, Ravingerová, T, Barancík, M

“…The study has been designed to characterize protein systems involved in the responses of rat hearts to chronic doxorubicin (DOX) treatment. We investigated the…”
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The effect of antioxidant treatment and NOS inhibition on the incidence of ischemia-induced arrhythmias in the diabetic rat heart by Matejíková, J, Kucharská, J, Pancza, D, Ravingerová, T

“…Contrary to clinical trials, experimental studies revealed that diabetes mellitus (DM) may initiate, besides increased myocardial vulnerability to…”
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Mitogen-activated protein kinases and their role in regulation of cellular processes by Strnisková, M, Barancík, M, Ravingerová, T

“…Mitogen-activated protein kinases (MAPKs) are evolutionary conserved enzymes connecting cell-surface receptors to critical regulatory targets within cells. The…”
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Pleiotropic, non-cell death-associated effects of inhibitors of receptor-interacting protein kinase 1 in the heart by Horvath, C., Szobi, A., Kindernay, L., Ravingerova, T., Adameova, A.

“…Inhibition of receptor-interacting protein kinase 1 (RIP1) has been recognized as a compelling tool for limiting necroptosis. Recent findings have indicated…”
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The effect of antioxidant treatment and NOS inhibition on the incidence of ischaemia-induced arrhythmias in the diabetic rat heart by Matejíková, J, Kucharská, J, Pancza, D, Ravingerová, T

“…Contrary to clinical trials, experimental studies revealed that diabetes mellitus (DM) may initiate, besides increased myocardial vulnerability to…”
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Preconditioning modulates susceptibility to ischemia-induced arrhythmias in the rat heart: the role of alpha-adrenergic stimulation and K(ATP) channels by Ravingerová, T, Pancza, D, Ziegelhoffer, A, Styk, J

“…A new concept of cardioprotection based on the exploitation of endogenous mechanisms is known as ischemic preconditioning (IPC). It has been hypothesized that…”
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Preventive and therapeutic application of molecular hydrogen in situations with excessive production of free radicals by Slezák, J, Kura, B, Frimmel, K, Zálešák, M, Ravingerová, T, Viczenczová, C, Okruhlicová, Ľ, Tribulová, N

“…Excessive production of oxygen free radicals has been regarded as a causative common denominator of many pathological processes in the animal kingdom. Hydroxyl…”
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Cardioprotective effects of quercetin against ischemia-reperfusion injury are age-dependent by Bartekova, M, Radosinska, J, Pancza, D, Barancik, M, Ravingerova, T

“…Quercetin, a polyphenolic compound present in various types of food, has been shown to exert beneficial effects in different cardiac as well as non-cardiac…”
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Hyperosmotic environment blunts effectivity of ischemic preconditioning against ischemia-reperfusion injury and improves ischemic tolerance in non-preconditioned isolated rat hearts by Zálešák, M, BlaŽíček, P, Pancza, D, Gablovský, I, Štrbák, V, Ravingerová, T

“…Several studies have shown that diabetes mellitus modulates heart resistance to ischemia and abrogates effectivity of cardioprotective interventions, such as…”
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Voluntary exercise may activate components of pro-survival risk pathway in the rat heart and potentially modify cell proliferation in the myocardium by Lonek, L, Puhova, A, Griecsova-Kindernay, L, Patel, S P, Zohdi, V, Jezova, D, Ravingerova, T

“…Although physical exercise is known to reduce size of infarction, incidence of ventricular arrhythmias, and to improve heart function, molecular mechanisms of…”
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Oxidative stress plays an important role in zoledronic acid-induced autophagy by Khandelwal, V K M, Mitrofan, L M, Hyttinen, J M T, Chaudhari, K R, Buccione, R, Kaarniranta, K, Ravingerová, T, Mönkkönen, J

“…Several pre-clinical and clinical studies have demonstrated zoledronic acid (Zol), which regulates the mevalonate pathway, has efficient anti-cancer effects…”
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Dual influence of spontaneous hypertension on membrane properties and ATP production in heart and kidney mitochondria in rat: effect of captopril and nifedipine, adaptation and dysadaptation by Ziegelhöffer, A, Mujkošová, J, Ferko, M, Vrbjar, N, Ravingerová, T, Uličná, O, Waczulíková, I, Ziegelhöffer, B

“…This study deals with changes, induced by hypertension and its treatment, in the function and properties of mitochondria in the heart and kidneys. Male,…”
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Effect of maturation on the resistance of rat hearts against ischemia. Study of potential molecular mechanisms by Griecsová, L, Farkašová, V, Gáblovský, I, Khandelwal, V K M, Bernátová, I, Tatarková, Z, Kaplan, P, Ravingerová, T

“…Reduced tolerance to ischemia/reperfusion (IR) injury has been shown in elder human and animal hearts, however, the onset of this unfavorable phenotype and…”
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Cardioprotection induced by remote ischemic preconditioning preserves the mitochondrial respiratory function in acute diabetic myocardium by Kancirová, I, Jašová, M, Muráriková, M, Sumbalová, Z, Uličná, O, Ravingerová, T, Waczulíková, I, Ziegelhöffer, A, Ferko, M

“…A 2×2 factorial design was used to evaluate possible preservation of mitochondrial functions in two cardioprotective experimental models, remote ischemic…”
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Remote ischemic preconditioning of the heart: protective responses in functional and biophysical properties of cardiac mitochondria by Ferko, M, Kancirová, I, Jašová, M, Čarnická, S, Muráriková, M, Waczulíková, I, Sumbalová, Z, Kucharská, J, Uličná, O, Ravingerová, T, Ziegelhöffer, A

“…Remote ischemic preconditioning (RIP)-induced protection of myocardial energetics was well documented on the level of tissue, but data concerning the…”
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Stimulation of mitochondrial ATP synthase activity - a new diazoxide-mediated mechanism of cardioprotection by Jašová, M, Kancirová, I, Muráriková, M, Farkašová, V, Waczulíková, I, Ravingerová, T, Ziegelhöffer, A, Ferko, M

“…Pharmacological preconditioning by diazoxide and a model of experimental streptozotocin-induced acute diabetes mellitus (STZ-DM) provided similar levels of…”
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Remote preconditioning as a novel "conditioning" approach to repair the broken heart: potential mechanisms and clinical applications by Ravingerova, T, Farkasova, V, Griecsova, L, Carnicka, S, Murarikova, M, Barlaka, E, Kolar, F, Bartekova, M, Lonek, L, Slezak, J, Lazou, A

“…Remote ischemic preconditioning (RIPC) is a novel strategy of protection against ischemia-reperfusion (IR) injury in the heart (and/or other organs) by brief…”
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Impaired PI3K/Akt signaling as a potential cause of failure to precondition rat hearts under conditions of simulated hyperglycemia by Zálešák, M, Blažíček, P, Gablovský, I, Ledvényiová, V, Barteková, M, Ziegelhöffer, A, Ravingerová, T

“…The aim of the study was to evaluate the impact of simulated acute hyperglycemia (HG) on PI3K/Akt signaling in preconditioned and non-preconditioned isolated…”
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Upregulation of genes involved in cardiac metabolism enhances myocardial resistance to ischemia/reperfusion in the rat heart by Ravingerová, T, Carnická, S, Ledvényiová, V, Barlaka, E, Galatou, E, Chytilová, A, Mandíková, P, Nemčeková, M, Adameová, A, Kolář, F, Lazou, A

“…Genes encoding enzymes involved in fatty acids (FA) and glucose oxidation are transcriptionally regulated by peroxisome proliferator-activated receptors…”
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