Search Results - "Ravikrishnan, Aparna"
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Region-specific Expression of NMDA Receptor GluN2C Subunit in Parvalbumin-Positive Neurons and Astrocytes: Analysis of GluN2C Expression using a Novel Reporter Model
Published in Neuroscience (01-06-2018)“…[Display omitted] •GluN2C is expressed in parvalbumin-positive neurons in a subset of basal ganglia nuclei.•GluN2C is localized to astrocytes in majority of…”
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Journal Article -
2
Differential effect of NMDA receptor GluN2C and GluN2D subunit ablation on behavior and channel blocker-induced schizophrenia phenotypes
Published in Scientific reports (20-05-2019)“…The GluN2C- and GluN2D-containing NMDA receptors are distinct from GluN2A- and GluN2B-containing receptors in many aspects including lower sensitivity to Mg 2+…”
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Journal Article -
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The NMDA receptor GluN2C subunit controls cortical excitatory-inhibitory balance, neuronal oscillations and cognitive function
Published in Scientific reports (06-12-2016)“…Despite strong evidence for NMDA receptor (NMDAR) hypofunction as an underlying factor for cognitive disorders, the precise roles of various NMDAR subtypes…”
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Journal Article -
4
Role of GluN2C-containing nmda receptors in cellular and behavioral deficits associated with corticothalamic circuit dysfunction in schizophrenia
Published 01-01-2015“…The NMDA receptor (NMDAR) hypofunction hypothesis in schizophrenia posits that reduced NMDAR function leads to behavioral abnormalities observed in…”
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Dissertation