Search Results - "Ravikrishnan, Anitha"

Poly(ethylene glycol)- block -cationic polylactide nanocomplexes of differing charge density for gene delivery by Chen, Chih-Kuang, Jones, Charles H, Mistriotis, Panagiotis, Yu, Yun, Ma, Xiaoni, Ravikrishnan, Anitha, Jiang, Ming, Andreadis, Stelios T, Pfeifer, Blaine A, Cheng, Chong

“…Abstract Representing a new type of biodegradable cationic block copolymer, well-defined poly(ethylene glycol)- block -cationic polylactides (PEG- b -CPLAs)…”
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Hybrid biosynthetic gene therapy vector development and dual engineering capacity by Jones, Charles H., Ravikrishnan, Anitha, Chen, Mingfu, Reddinger, Ryan, Ahmadi, Mahmoud Kamal, Rane, Snehal, Hakansson, Anders P., Pfeifer, Blaine A.

“…Genetic vaccines offer a treatment opportunity based upon successful gene delivery to specific immune cell modulators. Driving the process is the vector chosen…”
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Core–Shell Microfibers via Bioorthogonal Layer-by-Layer Assembly by Ravikrishnan, Anitha, Zhang, He, Fox, Joseph M, Jia, Xinqiao

“…A new technique is described for the construction of core–shell microfibers for biomedical applications. Fibrous scaffolds were fabricated by electrospinning,…”
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Mannosylated poly(beta-amino esters) for targeted antigen presenting cell immune modulation by Jones, Charles H, Chen, Mingfu, Ravikrishnan, Anitha, Reddinger, Ryan, Zhang, Guojian, Hakansson, Anders P, Pfeifer, Blaine A

“…Abstract Given the rise of antibiotic resistance and other difficult-to-treat diseases, genetic vaccination is a promising preventative approach that can be…”
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RGDSP-Decorated Hyaluronate Hydrogels Facilitate Rapid 3D Expansion of Amylase-Expressing Salivary Gland Progenitor Cells by Fowler, Eric W, Ravikrishnan, Anitha, Witt, Robert L, Pradhan-Bhatt, Swati, Jia, Xinqiao

“…engineering of salivary glands relies on the availability of synthetic matrices presenting essential cell-instructive signals to guide tissue growth. Here, we…”
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Overcoming Nonviral Gene Delivery Barriers: Perspective and Future by Jones, Charles H, Chen, Chih-Kuang, Ravikrishnan, Anitha, Rane, Snehal, Pfeifer, Blaine A

“…A key end goal of gene delivery research is to develop clinically relevant vectors that can be used to combat elusive diseases such as AIDS. Despite promising…”
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Regulating Cell Phenotype and Function Using Custom-Designed Synthetic Matrices by Ravikrishnan, Anitha

“…The natural extracellular matrix serves as a mechanical platform for cells and influences basic cellular functions. Using custom-designed, synthetic matrices,…”
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Regulation of Epithelial-to-Mesenchymal Transition Using Biomimetic Fibrous Scaffolds by Ravikrishnan, Anitha, Ozdemir, Tugba, Bah, Mohamed, Baskerville, Karen A, Shah, S. Ismat, Rajasekaran, Ayyappan K, Jia, Xinqiao

“…Epithelial-to-mesenchymal transition (EMT) is a well-studied biological process that takes place during embryogenesis, carcinogenesis, and tissue fibrosis…”
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Rapid Bioorthogonal Chemistry Enables in Situ Modulation of the Stem Cell Behavior in 3D without External Triggers by Hao, Ying, Song, Jiyeon, Ravikrishnan, Anitha, Dicker, Kevin T, Fowler, Eric W, Zerdoum, Aidan B, Li, Yi, Zhang, He, Rajasekaran, Ayyappan K, Fox, Joseph M, Jia, Xinqiao

“…Chemical modification of engineered microenvironments surrounding living cells represents a means for directing cellular behaviors through cell–matrix…”
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Structure–Function Assessment of Mannosylated Poly(β-amino esters) upon Targeted Antigen Presenting Cell Gene Delivery by Jones, Charles H, Chen, Mingfu, Gollakota, Akhila, Ravikrishnan, Anitha, Zhang, Guojian, Lin, Sharon, Tan, Myles, Cheng, Chong, Lin, Haiqing, Pfeifer, Blaine A

“…Antigen presenting cell (APC) gene delivery is a promising avenue for modulating immunological outcomes toward a desired state. Recently, our group developed a…”
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Influence of molecular weight upon mannosylated bio-synthetic hybrids for targeted antigen presenting cell gene delivery by Jones, Charles H, Gollakota, Akhila, Chen, Mingfu, Chung, Tai-Chun, Ravikrishnan, Anitha, Zhang, Guojian, Pfeifer, Blaine A

“…Abstract Given the rise of antibiotic resistant microbes, genetic vaccination is a promising prophylactic strategy that enables rapid design and manufacture…”
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Biomaterials-based strategies for salivary gland tissue regeneration by Ozdemir, Tugba, Fowler, Eric W, Hao, Ying, Ravikrishnan, Anitha, Harrington, Daniel A, Witt, Robert L, Farach-Carson, Mary C, Pradhan-Bhatt, Swati, Jia, Xinqiao

“…The salivary gland is a complex, secretory tissue that produces saliva and maintains oral homeostasis. Radiation induced salivary gland atrophy, manifested as…”
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PEGylated Cationic Polylactides for Hybrid Biosynthetic Gene Delivery by Jones, Charles H, Chen, Chih-Kuang, Chen, Mingfu, Ravikrishnan, Anitha, Zhang, Hanguang, Gollakota, Akhila, Chung, Taichun, Cheng, Chong, Pfeifer, Blaine A

“…Genetic vaccination is predicated on the underlying principle that diseases can be prevented by the controlled introduction of genetic material encoding…”
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Hydrogel-Supported, Engineered Model of Vocal Fold Epithelium by Ravikrishnan, Anitha, Fowler, Eric W, Stuffer, Alexander J, Jia, Xinqiao

“…There is a critical need for the establishment of an engineered model of the vocal fold epithelium that can be used to gain understanding of its role in vocal…”
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Functionalized Poly(beta-Amino Ester)s for development of next generation gene delivery vectors by Ravikrishnan, Anitha

“…A key end goal of gene delivery research is to develop clinically relevant vectors that can be used to combat elusive diseases such as AIDS. Despite promising…”
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Polymyxin B Treatment Improves Bactofection Efficacy and Reduces Cytotoxicity by Jones, Charles H, Rane, Snehal, Patt, Emily, Ravikrishnan, Anitha, Chen, Chih-Kuang, Cheng, Chong, Pfeifer, Blaine A

“…Improvements to bacterial vectors have resulted in nonviral gene therapy vehicles that are easily prepared and can achieve high levels of transfection…”
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