Search Results - "Ravichandran, Subramaniyam"
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G-quadruplex as an essential structural element in cytomegalovirus replication origin
Published in Nature communications (27-08-2024)“…G-quadruplex (G4) structures are found in eukaryotic cell replication origins, but their role in origin function remains unclear. In this study G4 motifs are…”
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G-quadruplexes formed by Varicella-Zoster virus reiteration sequences suppress expression of glycoprotein C and regulate viral cell-to-cell spread
Published in PLoS pathogens (01-01-2023)“…G-quadruplex (G4) formed by repetitive guanosine-rich sequences plays important roles in diverse cellular processes; however, its roles in viral infection are…”
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Unraveling the Regulatory G-Quadruplex Puzzle: Lessons From Genome and Transcriptome-Wide Studies
Published in Frontiers in genetics (18-10-2019)“…G-quadruplexes (G4s) are among the best-characterized DNA secondary structures and are enriched in regulatory regions, especially promoters, of several…”
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Genome-wide analysis of regulatory G-quadruplexes affecting gene expression in human cytomegalovirus
Published in PLoS pathogens (01-09-2018)“…G-quadruplex (G4), formed by repetitive guanosine-rich sequences, is known to play various key regulatory roles in cells. Herpesviruses containing a large…”
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Stabilization of RNA G-quadruplexes in the SARS-CoV-2 genome inhibits viral infection via translational suppression
Published in Archives of pharmacal research (01-07-2023)“…The G-quadruplex (G4) formed in single-stranded DNAs or RNAs plays a key role in diverse biological processes and is considered as a potential antiviral…”
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Pneumococcal VncR Strain-Specifically Regulates Capsule Polysaccharide Synthesis
Published in Frontiers in microbiology (01-10-2019)“…Capsular polysaccharides (CPS), a major virulence factor in Streptococcus pneumoniae , become thicker during blood invasion while not during asymptomatic…”
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Chemical-induced formation of BZ-junction with base extrusion
Published in Biochemical and biophysical research communications (22-01-2019)“…The crystal structure of BZ-junction reveals that left-handed Z-DNA stabilized by Z-DNA binding domain (Zα) is continuously stacked to right-handed B-DNA with…”
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The effect of hairpin loop on the structure and gene expression activity of the long-loop G-quadruplex
Published in Nucleic acids research (11-10-2021)“…G-quadruplex (G4), a four-stranded DNA or RNA structure containing stacks of guanine tetrads, plays regulatory roles in many cellular functions. So far,…”
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Z-DNA in the genome: from structure to disease
Published in Biophysical reviews (01-06-2019)“…The scope of studies investigating the architecture of genomic DNA has progressed steadily since the elucidation of the structure of B-DNA. In recent years,…”
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Correction to ‘The effect of hairpin loop on the structure and gene expression activity of the long-loop G-quadruplex’
Published in Nucleic acids research (18-11-2021)Get full text
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A novel approach for the biosynthesis of silver oxide nanoparticles using aqueous leaf extract of Callistemon lanceolatus (Myrtaceae) and their therapeutic potential
Published in Journal of experimental nanoscience (12-04-2016)“…This study describes a novel biological route for the biosynthesis of silver oxide nanoparticles utilising the aqueous extract of Callistemon lanceolatus D.C…”
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Abstract LB430: Identification of therapeutic target in breast cancer using G-quadruplex binding ligands
Published in Cancer research (Chicago, Ill.) (05-04-2024)“…Abstract G-quadruplex (G4) motifs are noncanonical nucleic acid structures formed from staked guanine rich tetrads. G4 motifs have been shown to play…”
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Bioinorganic Nanohybrid Catalyst for Multistep Synthesis of Acetaminophen, an Analgesic
Published in ACS applied materials & interfaces (09-11-2016)“…A bioinorganic nanohybrid catalyst was synthesized by combining esterase with a platinum nanoparticle (PtNP). The combination of two catalysts resulted in…”
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