Search Results - "Ravichandran, Anjali J."

Cell-Based Determination of Neutralizing Antibodies Against Adeno-Associated Virus in Cardiac Gene Therapy by Ravichandran, Anjali J, Mazurek, Renata, Ishikawa, Kiyotake

“…The field of cardiac gene therapy has seen the rising use of adeno-associated viral (AAV) vectors as a promising therapeutic option for cardiac diseases and…”
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Reduction of left ventricular diastolic pressure as a key regulator of infarct coronary flow under mechanical left ventricular support by Sakata, Tomoki, Mavropoulos, Spyros A., Mazurek, Renata, Romeo, Francisco J., Ravichandran, Anjali J., Marx, Jonas M., Kariya, Taro, Ishikawa, Kiyotake

“…Restoring ischaemic myocardial tissue perfusion is crucial for minimizing infarct size. Acute mechanical left ventricular (LV) support has been suggested to…”
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Impact of ischemia on left atrial remodeling and dysfunction in swine models of mitral regurgitation by Sakata, Tomoki, Mazurek, Renata, Mavropoulos, Spyros A, Romeo, Francisco J, Ravichandran, Anjali J, Watanabe, Shin, Kariya, Taro, Ishikawa, Kiyotake

“…Left atrial (LA) dysfunction is one of the predictive factors of worse outcomes after mitral valve surgery for mitral regurgitation (MR). We aimed to…”
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Barriers in Heart Failure Gene Therapy and Approaches to Overcome Them by Ravichandran, Anjali J., Romeo, Francisco J., Mazurek, Renata, Ishikawa, Kiyotake

“…With the growing prevalence and incidence of heart failure worldwide, investigation and development of new therapies to address disease burden are of great…”
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Assessing the Effect of Cardiac Gene Therapy Using Catheter-Based Pressure-Volume Measurement in Large Animals by Sakata, Tomoki, Mazurek, Renata, Mavropoulos, Spyros A, Romeo, Francisco J, Ravichandran, Anjali J, Ishikawa, Kiyotake

“…Gene therapy for heart failure targets various pathways that modulate cardiac function. Its detailed evaluation is crucial for proving the efficacy of cardiac…”
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Negative Impact of Acute Reloading after Mechanical Left Ventricular Unloading by Mazurek, Renata, Kariya, Taro, Sakata, Tomoki, Mavropoulos, Spyros A., Ravichandran, Anjali J., Romeo, Francisco J., Yamada, Kelly P., Ishikawa, Kiyotake

“…Mechanical LV unloading for acute myocardial infarction (MI) is a promising supportive therapy to reperfusion. However, no data is available on exit strategy…”
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Abstract 18817: Dysregulation of Key Calcium Cycling Genes Does Not Drive Right Heart Maladaptation in a Porcine PH Model by Ravichandran, Anjali J, Mazurek, Renata, Mavropoulos, Spyros, Sakata, Tomoki, Ishikawa, Kiyotake, Marx, Jonas

“…Abstract only Introduction: Pulmonary hypertension (PH), a complex disease characterized by an elevated pulmonary artery pressure, causes maladaptation in…”
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Understanding the Role of Calcium Cycling Genes in Maladaptation of the Right Heart in Response to Pulmonary Hypertension by Ravichandran, Anjali J

“…Pulmonary hypertension (PH), a complex disease characterized by an elevated pulmonary artery pressure, causes severe right heart remodeling and failure in…”
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