Search Results - "Ravi Kumar, V N"

Design of Biodegradable Nanoparticles for Oral Delivery of Doxorubicin: In vivo Pharmacokinetics and Toxicity Studies in Rats by Kalaria, D. R, Sharma, G, Beniwal, V, Ravi Kumar, M. N. V

“…Purpose Doxorubicin, a potent anticancer drug associated with cardiotoxicity and low oral bioavailability, was loaded into nanoparticles with a view to improve…”
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Can Controversial Nanotechnology Promise Drug Delivery? by Devadasu, Venkat Ratnam, Bhardwaj, Vivekanand, Kumar, M. N. V. Ravi

“…The use of nanotechnology in drug delivery is investigated. Data suggest that nanotechnology holds promise as a drug delivery method, although it must be noted…”
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Therapeutic Potential of Natural Antioxidants by Ramana, Kota V., Reddy, Aramati B. M., Majeti, N. V. Ravi Kumar, Singhal, Sharad S.

“…Natural antioxidants are the plants- and other living organism-derived compounds with a strong potential to inhibit oxidative stress by controlling the…”
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Development of biodegradable nanoparticles for oral delivery of ellagic acid and evaluation of their antioxidant efficacy against cyclosporine a-induced nephrotoxicity in rats by SONAJE, K, ITALIA, J. L, SHARMA, G, BHARDWAJ, V, TIKOO, K, RAVI KUMAR, M. N. V

“…Ellagic acid (EA), a dietary antioxidant associated with poor biopharmaceutical properties, was encapsulated into poly(lactide-co-glycolide) (PLGA) and…”
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Effect of SiC particle content on foaming and mechanical properties of remelted and diluted A356/SiC composite by RAVI KUMAR, N. V, RAMACHANDRA RAO, N, GOKHALE, A. A

“…A commercial Al-Si-Mg composite was diluted to different SiC (mean size: 8 mu m) contents, and was foamed using TiH2 by melt based technique at a fixed foaming…”
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Double-headed nanosystems for oral drug delivery by Kaur, G, Arora, M, Ganugula, R, Kumar, M N V Ravi

“…We demonstrate a novel strategy to engineer double-headed nanosystems by chemical modification of the carboxyl terminal polyester with a linker that offers…”
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Glucose-Responsive Microgel Comprising Conventional Insulin and Curcumin-Laden Nanoparticles: a Potential Combination for Diabetes Management by Heyns, Ingrid M., Davis, Garrett, Ganugula, Raghu, Ravi Kumar, M. N. V., Arora, Meenakshi

“…Successful management of type 2 diabetes mellitus (T2DM), a complex and chronic disease, requires a combination of anti-hyperglycemic and anti-inflammatory…”
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Low-Dose Curcumin Nanoparticles Normalise Blood Pressure in Male Wistar Rats with Diet-Induced Metabolic Syndrome by du Preez, Ryan, Pahl, Jessica, Arora, Meenakshi, Ravi Kumar, M N V, Brown, Lindsay, Panchal, Sunil K

“…Nanoparticle formulations improve bioavailability and so may allow low-dose formulations of food-derived compounds such as curcumin to attenuate chronic…”
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Design of estradiol loaded PLGA nanoparticulate formulations : A potential oral delivery system for hormone therapy by HARIHARAN, S, BHARDWAJ, V, BALA, I, SITTERBERG, J, BAKOWSKY, U, RAVI KUMAR, M. N. V

“…Estradiol (E2), a highly lipophilic molecule with good oral absorption but poor oral bioavailability, was incorporated into poly(lactide-co-glycolide) (PLGA)…”
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PLGA Nanoparticles Stabilized with Cationic Surfactant: Safety Studies and Application in Oral Delivery of Paclitaxel to Treat Chemical-Induced Breast Cancer in Rat by Bhardwaj, V, Ankola, D. D, Gupta, S. C, Schneider, M, Lehr, C.-M, Kumar, M. N. V. Ravi

“…Purpose This study was carried out to formulate poly(lactide-co-glycolide) (PLGA) nanoparticles using a quaternary ammonium salt didodecyl dimethylammonium…”
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Foaming experiments on LM25 alloy reinforced with SiC particulates by Ravi Kumar, N.V., Ramachandra Rao, N., Sudhakar, B., Gokhale, A.A.

“…▶ Good quality Al–Si–Mg/SiCP foams were prepared by melt processing route with TiH2 as the blowing agent. ▶ It is observed that irrespective of the particle…”
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Biodegradable Nanoparticles Improve Oral Bioavailability of Amphotericin B and Show Reduced Nephrotoxicity Compared to Intravenous Fungizone by Italia, J. L, Yahya, M. M, Singh, D, Ravi Kumar, M. N. V

“…Purpose Amphotericin B (AMB), an effective antifungal and antileishmanial agent associated with low oral bioavailability (0.3%) and severe nephrotoxicity, was…”
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Pharmacodynamic Evaluation of Oral Estradiol Nanoparticles in Estrogen Deficient (Ovariectomized) High-Fat Diet Induced Hyperlipidemic Rat Model by Mittal, G, Chandraiah, G, Ramarao, P, Ravi Kumar, M. N. V

“…Purpose It is believed that estrogen deficiency contributes importantly to the pathogenesis of menopausal metabolic syndrome and symptoms can be ameliorated…”
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Chitosan Chemistry and Pharmaceutical Perspectives by Kumar, M. N. V. Ravi, Muzzarelli, R. A. A, Muzzarelli, C, Sashiwa, H, Domb, A. J

“…Chitosan is a safe and friendly substance for the human organism. Kumar et al provide interdisciplinary insight in the scientific knowledge immediately usable…”
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ZnPP‐laden nanoparticles improve glucose homeostasis and chronic inflammation during obesity by Yang, Wanbao, Arora, Meenakshi, Han, Hye Won, Jiang, Wen, Kim, Da Mi, Ai, Weiqi, Pan, Quan, Kumar, M. N. V. Ravi, Brashear, Wesley A., Sun, Yuxiang, Guo, Shaodong

“…Background and Purpose Chronic inflammation plays a pivotal role in the development of Type 2 diabetes mellitus (T2DM). Previous studies have shown that haem…”
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Evaluating the potential of polyester nanoparticles for per oral delivery of amphotericin B in treating visceral leishmaniasis by Italia, J L, Kumar, M N V Ravi, Carter, K C

“…Leishmaniasis is a protozoan disease, which is responsible for response for major epidemics in many parts of the World. Amphotericin B (AMB) is one of the…”
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Next-Generation Noncompetitive Nanosystems Based on Gambogic Acid: In Silico Identification of Transferrin Receptor Binding Sites, Regulatory Shelf Stability, and Their Preliminary Safety in Healthy Rodents by Arora, M, Ganugula, R, Kumar, N, Kaur, G, Pellois, J.-P, Garg, P, Ravi Kumar, M. N. V

“…A major challenge in drug delivery is to enhance the transport of drugs across biological barriers, such as the small intestine, the blood–brain barrier, and…”
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Efficacy of biodegradable curcumin nanoparticles in delaying cataract in diabetic rat model by Grama, Charitra N, Suryanarayana, Palla, Patil, Madhoosudan A, Raghu, Ganugula, Balakrishna, Nagalla, Kumar, M N V Ravi, Reddy, Geereddy Bhanuprakash

“…Curcumin, the active principle present in the yellow spice turmeric, has been shown to exhibit various pharmacological actions such as antioxidant,…”
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Nanoparticle encapsulation improves oral bioavailability of curcumin by at least 9-fold when compared to curcumin administered with piperine as absorption enhancer by Shaikh, J., Ankola, D.D., Beniwal, V., Singh, D., Kumar, M.N.V. Ravi

“…Curcumin, a derived product from common spice turmeric that is safe and beneficial in several aliments was formulated into biodegradable nanoparticles with a…”
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Effect of hafnium incorporation on the crystallization and mechanical behavior of a Zr-based bulk amorphous alloy by Baldwin, F., Ravi Kumar, N.V., Das, K., Bandyopadhyay, A., Gupta, Y.M.

“…The crystallization and mechanical behavior of a hafnium-containing bulk amorphous alloy (Hf 28.35Zr 28.35Cu 15.3Ni 12.5Nb 5.0Al 10.0Y 0.5) was investigated…”
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