Search Results - "Ravert, H. T."

PET imaging of the dopamine transporter in progressive supranuclear palsy and Parkinson's disease by ILGIN, N, ZUBIETA, J, REICH, S. G, DANNALS, R. F, RAVERT, H. T, FROST, J. J

“…To differentiate the patterns of dopamine transporter loss between idiopathic PD and progressive supranuclear palsy (PSP). We used the radiotracer [11C]-WIN…”
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Dopamine Transporters are Markedly Reduced in Lesch-Nyhan Disease in vivo by Wong, Dean F., Harris, James C., Naidu, Sakkubai, Yokoi, Fuji, Marenco, Stefano, Dannals, Robert F., Ravert, Hayden T., Yaster, Myron, Evans, Alan, Rousset, Olivier, Bryan, R. Nick, Gjedde, Albert, Kuhar, Michael J., Breese, George R.

“…Dopamine (DA) deficiency has been implicated in Lesch-Nyhan disease (LND), a genetic disorder that is characterized by hyperuricemia, choreoathetosis,…”
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Increased mu opioid receptor binding detected by PET in cocaine-dependent men is associated with cocaine craving by Zubieta, Jon-Kar, Gorelick, David A, Stauffer, Robin, Ravert, Hayden T, Dannals, Robert F, Frost, J. James

“…The endogenous opioid system has been recently implicated in the reinforcing actions of cocaine and other addictive drugs. In this study we examined mu opioid…”
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Kinetic Analysis of [ C]McN5652: A Serotonin Transporter Radioligand by Szabo, Zsolt, Scheffel, Ursula, Mathews, William B., Ravert, Hayden T., Szabo, Katalina, Kraut, Michael, Palmon, Sally, Ricaurte, George A., Dannals, Robert F.

“…The impulse response function of a radioligand is the most fundamental way to describe its pharmacokinetics and to assess its tissue uptake and retention…”
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Cognition and Amyloid Load in Alzheimer Disease Imaged With Florbetapir F 18(AV-45) Positron Emission Tomography by Rosenberg, Paul B., M.D, Wong, D.F, Edell, S.L, Ross, J.S, Joshi, A.D, Brašić, J.R, Zhou, Y, Raymont, V, Kumar, A, Ravert, H.T, Dannals, R.F, Pontecorvo, M.J, Skovronsky, D.M, Lyketsos, C.G

“…Objective To examine the association between regional brain uptake of a novel amyloid positron emission tomography (PET) tracer florbetapir F 18 ([18 F]-AV-45)…”
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D2-Like Dopamine Receptor Density in Tourette Syndrome Measured by PET by Wong, Dean F, Singer, Harvey S, Brandt, Jason, Shaya, Elias, Chen, Catherine, Brown, Jan, Kimball, A.W, Gjedde, Albert, Dannals, Robert F, Ravert, Hayden T, Wilson, P. David, Wagner, Henry N., Jr

“…Tourette syndrome (TS) is a chronic neurologic disorder characterized by the presence of involuntary motor and phonic tics. There is evidence that TS is…”
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PET imaging of opioid receptors in pain: progress and new directions by Ravert, Hayden T, Bencherif, Badreddine, Madar, Igal, Frost, J James

“…The endogenous opioid system plays a central role in pain. Recent advances have permitted imaging of opioid receptors by PET in human subjects while…”
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Brain opioid receptor measurements by positron emission tomography in normal cycling women : Relationship to luteinizing hormone pulsatility and gonadal steroid hormones by SMITH, Y. R, ZUBIETA, J.-K, DEL CARMEN, M. G, DANNALS, R. F, RAVERT, H. T, ZACUR, H. A, FROST, J. J

“…The regulation of central mu-opioid receptors in women during the menstrual cycle was explored with positron emission tomography and the selective radiotracer…”
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Imaging of delta- and mu-opioid receptors in temporal lobe epilepsy by positron emission tomography by Madar, I, Lesser, R P, Krauss, G, Zubieta, J K, Lever, J R, Kinter, C M, Ravert, H T, Musachio, J L, Mathews, W B, Dannals, R F, Frost, J J

“…The involvement of opioid neurotransmitter systems in seizure mechanisms is well documented. In previous positron emission tomography (PET) studies in patients…”
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Fluorine-18-FPH for PET Imaging of Nicotinic Acetylcholine Receptors by Horti, Andrew, Scheffel, Ursula, Stathis, Marigo, Finley, Paige, Ravert, Hayden T, London, EdyD, Dannals, Robert F

“…Visualization of central nicotinic acetylcholine receptors (nAChRs) with modern PET or SPECT imaging techniques has been hampered by the lack of a radioligand…”
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Multicompartmental analysis of [11C]-carfentanil binding to opiate receptors in humans measured by positron emission tomography by Frost, J J, Douglass, K H, Mayberg, H S, Dannals, R F, Links, J M, Wilson, A A, Ravert, H T, Crozier, W C, Wagner, Jr, H N

“…[11C]-Carfentanil is a high affinity opiate agonist that can be used to localize mu opiate receptors in humans by positron emission tomography (PET). A…”
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Synthesis and Evaluation of N-[11C]Methylated Analogues of Epibatidine as Tracers for Positron Emission Tomographic Studies of Nicotinic Acetylcholine Receptors by Horti, Andrew G, Scheffel, Ursula, Kimes, Alane S, Musachio, John L, Ravert, Hayden T, Mathews, William B, Zhan, Yougen, Finley, Paige A, London, Edythe D, Dannals, Robert F

“…Four halogen-substituted analogues of N-methylepibatidine, a nicotinic acetylcholine receptor (nAChR) ligand, were synthesized. They were…”
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Imaging Nicotinic Acetylcholine Receptors with Fluorine-18-FPH, an Epibatidine Analog by Villemagne, Victor L, Horti, Andrew, Scheffel, Ursula, Ravert, Hayden T, Finley, Paige, Clough, David J, London, EdyD, Wagner, Henry N., Jr, Dannals, Robert F

“…Nicotinic acetylcholine receptors (nAChRs) have been implicated in a variety of central processes, such as learning and memory and analgesia. These receptors…”
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2-[ 18F]fluoro-A-85380, an in vivo tracer for the nicotinic acetylcholine receptors by Horti, Andrew G, Scheffel, Ursula, Koren, Andrei O, Ravert, Hayden T, Mathews, William B, Musachio, John L, Finley, Paige A, London, Edythe D, Dannals, Robert F

“…The in vivo brain regional distribution of 2-[ 18F]fluoro-A-85380, a novel tracer for positron emission tomographic (PET) studies, followed the regional…”
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Enhanced Uptake of [11C]TPMP in Canine Brain Tumor: A PET Study by Madar, Igal, Anderson, James H, Szabo, Zsolt, Scheffel, Ursula, Kao, Pan-Fu, Ravert, Hayden T, Dannals, Robert F

“…In vitro studies have demonstrated the membrane potential-dependent enhanced uptake of phosphonium salts, including [3H]triphenylmethylphosphonium (TPMP), into…”
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In Vivo Labeling of Endothelin Receptors with [11C]L-753,037: Studies in Mice and a Dog by Aleksic, Sasa, Szabo, Zsolt, Scheffel, Ursula, Ravert, Hayden T, Mathews, William B, Kerenyi, Levente, Rauseo, Paige A, Gibson, Raymond E, Burns, H. Donald, Dannals, Robert F

“…Endothelin (ET) is a potent mammalian vasoconstrictive peptide and a pressor agent. Its 3 isoforms, ET-1, ET-2, and ET-3, mediate several physiologic actions…”
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Positron emission tomography reveals elevated D2 dopamine receptors in drug-naive schizophrenics by WONG, D. F, WAGNER, H. N. JR, TOUNG, J. K. T, MALAT, J, WILLIAMS, J. A, Oï'TUAMA, L. A, SNYDER, S. H, TUNE, L. E, DANNALS, R. F, PEARLSON, G. D, LINKS, J. M, TAMMINGA, C. A, BROUSSOLLE, E. P, RAVERT, H. T, WILSON, A. A

“…In postmortem studies of patients with schizophrenia, D2 dopamine receptors in the basal ganglia have been observed to be more numerous than in patients with…”
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Mu-opiate receptors measured by positron emission tomography are increased in temporal lobe epilepsy by Frost, J J, Mayberg, H S, Fisher, R S, Douglass, K H, Dannals, R F, Links, J M, Wilson, A A, Ravert, H T, Rosenbaum, A E, Snyder, S H

“…Neurochemical studies in animal models of epilepsy have demonstrated the importance of multiple neurotransmitters and their receptors in mediating seizures…”
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Time Course of 5-HT2A Receptor Occupancy in the Human Brain after a Single Oral Dose of the Putative Antipsychotic Drug MDL 100,907 Measured by Positron Emission Tomography by Gründer, M.D, Gerhard, Yokoi, M.D, Fuji, Offord, Ph.D, Steve J., Ravert, Ph.D, Hayden T., Dannals, Ph.D, Robert F., Salzmann, M.S, Joanne K., Szymanski, D.O, Sally, Wilson, Ph.D, P.David, Howard, Ph.D, Daniel R., Wong, M.D., Ph.D, Dean F.

“…MDL 100,907 is a potent and selective antagonist of 5-HT2A serotonin receptors. Animal studies suggest that MDL 100,907 may behave as an atypical antipsychotic…”
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Longer Occupancy of Opioid Receptors by Nalmefene Compared to Naloxone as Measured In Vivo by a Dual-Detector System by Kim, Stanley, Wagner, Henry N., Jr, Villemagne, Victor L, Kao, Pan-Fu, Dannals, Robert F, Ravert, Hayden T, Joh, Tenshang, Dixon, Rosina B, Civelek, A. Cahid

“…Surgical procedures usually involve the administration of narcotic drugs as anesthetics or adjuvants. To reverse the effects of anesthesia, opioid antagonists…”
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