Search Results - "Ravelo, Angel G"
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Dichloromethane as a Solvent for Lipid Extraction and Assessment of Lipid Classes and Fatty Acids from Samples of Different Natures
Published in Journal of agricultural and food chemistry (25-06-2008)“…The usefulness of the solvent mixture dichloromethane/methanol for lipid extraction and the determination of lipid classes and fatty acids in samples of…”
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β‑Agarofurans and Sesquiterpene Pyridine Alkaloids from Maytenus spinosa
Published in Journal of natural products (Washington, D.C.) (22-08-2014)“…Nine new β-dihydroagarofurans (1–9) and four new sesquiterpene pyridine alkaloids (10–13) were isolated from the leaves of Maytenus spinosa. Their structures…”
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Antiproliferative and Structure Activity Relationships of Amaryllidaceae Alkaloids
Published in Molecules (Basel, Switzerland) (30-07-2015)“…The antiproliferative activity of a set of seven natural Amaryllidaceae alkaloids and 32 derivatives against four cancer cell lines (A2780, SW1573, T47-D and…”
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Multicomponent Synthesis of Antibacterial Dihydropyridin and Dihydropyran Embelin Derivatives
Published in Journal of organic chemistry (16-08-2013)“…A series of dihydropyran and dihydropyridin embelin derivatives were synthesized through a novel and straightforward one-pot protocol based on a…”
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Synthesis and antimalarial activity of new haemanthamine-type derivatives
Published in Bioorganic & medicinal chemistry (15-09-2012)“…Thirty one derivatives were prepared from the natural alkaloids haemanthamine (1), haemanthidine (2) and 11-hydroxyvittatine (3). They were evaluated for their…”
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Synthesis and Anti-HIV Activity of Lupane and Olean-18-ene Derivatives. Absolute Configuration of 19,20-Epoxylupanes by VCD
Published in Journal of natural products (Washington, D.C.) (27-04-2012)“…Lupane triterpenoids 2 and 5–12 and oleanene derivatives 13 and 14 were prepared from lupeol (1), betulin (3), and germanicol (4). They were tested for…”
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Synthesis and antiplasmodial activity of lycorine derivatives
Published in Bioorganic & medicinal chemistry (01-07-2010)“…Twenty seven lycorine derivatives were prepared and evaluated for their in vitro antimalarial activity against chloroquine-sensitive strains of Plasmodium…”
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Benzodihydrofurans from Cyperus teneriffae
Published in Journal of natural products (Washington, D.C.) (27-05-2011)“…Three new benzodihydrofurans (1–3) and seven known aromatic compounds (4–10) were isolated from the roots of Cyperus teneriffae. Vibrational circular dichroism…”
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Achyrofuran is an antibacterial agent capable of killing methicillin-resistant vancomycin-intermediate Staphylococcus aureus in the nanomolar range
Published in Phytomedicine (Stuttgart) (15-01-2013)“…Currently, there is a pressing need for novel antibacterial agents against drug-resistant bacteria, especially those which have been common in our communities…”
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Synthesis and study of antiproliferative, antitopoisomerase II, DNA-intercalating and DNA-damaging activities of arylnaphthalimides
Published in Bioorganic & medicinal chemistry (01-11-2013)“…A series of arylnaphthalimides were designed and synthesized to overcome the dose-limiting cytotoxicity of N-acetylated metabolites arising from amonafide, the…”
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Recent studies on natural products as anticancer agents
Published in Current topics in medicinal chemistry (2004)“…Cancer will be the major cause of death in the 21st century and natural products should provide novel and more effective anticancer agents. This review deals…”
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Cytotoxic Triterpenoids from Maytenus retusa
Published in Journal of natural products (Washington, D.C.) (27-12-2010)“…Seven new triterpenoids (1−7) and 36 known compounds were isolated from the root bark of Maytenus retusa. Their structures were determined by 1D and 2D…”
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Synthesis and anti-inflammatory activity of ent-kaurene derivatives
Published in European journal of medicinal chemistry (01-04-2011)“…A series of kaurene derivatives ( 1– 63) were prepared and evaluated for anti-inflammatory activity. Thirteen of the tested compounds were able to inhibit NO…”
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Preparation and antimalarial activity of semisynthetic lycorenine derivatives
Published in European journal of medicinal chemistry (01-05-2013)“…A set of twenty one lycorenine derivatives has been prepared from the alkaloid hippeastrine (1). The modifications performed on hippeastrine included some…”
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Preparation, anticholinesterase activity and molecular docking of new lupane derivatives
Published in Bioorganic & medicinal chemistry (01-07-2014)“…A series of twenty-one lupane derivatives were synthesized from the natural triterpenoid calenduladiol (1) and evaluated for acetyl- and butyrylcholinesterase…”
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Echium acanthocarpum hairy root cultures, a suitable system for polyunsaturated fatty acid studies and production
Published in BMC biotechnology (27-04-2011)“…The therapeutic and health promoting role of highly unsaturated fatty acids (HUFAs) from fish, i.e. eicosapentaenoic acid (EPA, 20:5n-3) and docosahexaenoic…”
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Triterpenoids and a Lignan from the Aerial Parts of Maytenus apurimacensis
Published in Journal of natural products (Washington, D.C.) (26-06-2009)“…Five new triterpenes (1−5) and one new lignan (6) were isolated from the aerial parts of Maytenus apurimacensis. Their structures were determined on the basis…”
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New terpenoids from Maytenus apurimacensis as MDR reversal agents in the parasite Leishmania
Published in Bioorganic & medicinal chemistry (01-02-2008)“…Two new sesquiterpenes ( 1– 2) and one new lupane triterpene ( 3) have been isolated from the roots of Maytenus apurimacensis. The novel β-dihydroagarofurans…”
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Cloning, characterization and analysis of expression profiles of a cDNA encoding a hyoscyamine 6β-hydroxylase (H6H) from Atropa baetica Willk
Published in Plant physiology and biochemistry (2009)“…A new cDNA encoding hyoscyamine 6β-hydroxylase (H6H, EC 1.14.11.11), a bifunctional enzyme catalyzing the last two steps in the biosynthesis of scopolamine,…”
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