Search Results - "Ravel, Patrice"

Application of modular response analysis to medium- to large-size biological systems by Mekedem, Meriem, Ravel, Patrice, Colinge, Jacques

“…The development of high-throughput genomic technologies associated with recent genetic perturbation techniques such as short hairpin RNA (shRNA), gene…”
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Tim-3 Expression on Tumor-Infiltrating PD-1 + CD8 + T Cells Correlates with Poor Clinical Outcome in Renal Cell Carcinoma by Granier, Clémence, Dariane, Charles, Combe, Pierre, Verkarre, Virginie, Urien, Saïk, Badoual, Cécile, Roussel, Hélène, Mandavit, Marion, Ravel, Patrice, Sibony, Mathilde, Biard, Lucie, Radulescu, Camélia, Vinatier, Emeline, Benhamouda, Nadine, Peyromaure, Michael, Oudard, Stéphane, Méjean, Arnaud, Timsit, Marc-Olivier, Gey, Alain, Tartour, Eric

“…Inhibitory receptors expressed by T cells mediate tolerance to tumor antigens, with coexpression of these receptors exacerbating this dysfunctional state…”
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An R package for generic modular response analysis and its application to estrogen and retinoic acid receptor crosstalk by Jimenez-Dominguez, Gabriel, Ravel, Patrice, Jalaguier, Stéphan, Cavaillès, Vincent, Colinge, Jacques

“…Modular response analysis (MRA) is a widely used inference technique developed to uncover directions and strengths of connections in molecular networks under a…”
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Long-term follow-up of DYT1 dystonia patients treated by deep brain stimulation: An open-label study by Cif, Laura, Vasques, Xavier, Gonzalez, Victoria, Ravel, Patrice, Biolsi, Brigitte, Collod-Beroud, Gwenaelle, Tuffery-Giraud, Sylvie, Elfertit, Hassan, Claustres, Mireille, Coubes, Philippe

“…Long‐term efficacy of internal globus pallidus (GPi) deep‐brain stimulation (DBS) in DYT1 dystonia and disease progression under DBS was studied. Twenty‐six…”
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Modeling the Dynamic of Multiwave Diseases: The Model of Hand, Foot and Mouth Disease by Ravel, Patrice, Duy, Nghia Ngu, Kister, Guilhem, Huong, Le Thi Song, Dwivedi, Ankit, Devaux, Christian A, Duong, Tran Nhu, Hien, Nguyen Tran, Gavotte, Laurent, Cornillot, Emmanuel, Frutos, Roger

“…An HFMD outbreak spread over the city of Hải Phòng from summer 2011 to autumn 2012. This epidemic was chosen because it was the very first HFMD epidemic in…”
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FT-GPI, a highly sensitive and accurate predictor of GPI-anchored proteins, reveals the composition and evolution of the GPI proteome in Plasmodium species by Sauer, Lena M, Canovas, Rodrigo, Roche, Daniel, Shams-Eldin, Hosam, Ravel, Patrice, Colinge, Jacques, Schwarz, Ralph T, Ben Mamoun, Choukri, Rivals, Eric, Cornillot, Emmanuel

“…Protozoan parasites are known to attach specific and diverse group of proteins to their plasma membrane via a GPI anchor. In malaria parasites, GPI-anchored…”
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Design and selection of optimal ErbB-targeting bispecific antibodies in pancreatic cancer by Rabia, Emilia, Garambois, Véronique, Dhommée, Christine, Larbouret, Christel, Lajoie, Laurie, Buscail, Yoan, Jimenez-Dominguez, Gabriel, Choblet-Thery, Sylvie, Liaudet-Coopman, Emmanuelle, Cerutti, Martine, Jarlier, Marta, Ravel, Patrice, Gros, Laurent, Pirot, Nelly, Thibault, Gilles, Zhukovsky, Eugene A, Gérard, Pierre-Emmanuel, Pèlegrin, André, Colinge, Jacques, Chardès, Thierry

“…The ErbB family of receptor tyrosine kinases is a primary target for small molecules and antibodies for pancreatic cancer treatment. Nonetheless, the current…”
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Monitoring the Influence of Hand, Foot, and Mouth Disease: New Guidelines on Patient Care during the 2011-2012 Multiwaves and Multivariant Outbreak in Hai Phong City, Vietnam by Duy, Nghia Ngu, Huong, Le Thi Thanh, Ravel, Patrice, Huong, Le Thi Song, Dwivedi, Ankit, Kister, Guilhem, Gavotte, Laurent, Devaux, Christian A, Thiem, Vu Dinh, Thanh, Nguyen Thi Hien, Duong, Tran Nhu, Hien, Nguyen Tran, Cornillot, Emmanuel, Frutos, Roger

“…From 2011 to 2012, Northern Vietnam suffered its first large-scale hand, foot, and mouth disease (HFMD) epidemic. Two sets of official guidelines were issued…”
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Chemoradiation triggers antitumor Th1 and tissue resident memory-polarized immune responses to improve immune checkpoint inhibitors therapy by Lauret Marie Joseph, Elodie, Kirilovsky, Amos, Lecoester, Benoît, El Sissy, Carine, Boullerot, Laura, Rangan, Laurie, Marguier, Amélie, Tochet, Florent, Dosset, Magalie, Boustani, Jihane, Ravel, Patrice, Boidot, Romain, Spehner, Laurie, Haicheur-Adjouri, Nacilla, Marliot, Florence, Pallandre, Jean-René, Bonnefoy, Francis, Scripcariu, Viorel, Van den Eynde, Marc, Cornillot, Emmanuel, Mirjolet, Céline, Pages, Franck, Adotevi, Olivier

“…BackgroundMultiple synergistic combination approaches with cancer drugs are developed to overcome primary resistance to immunotherapy; however, the mechanistic…”
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Cytokine profile of anti-spike CD4+T cells predicts humoral and CD8+T cell responses after anti-SARS-CoV-2 mRNA vaccination by Benhamouda, Nadine, Besbes, Anissa, Bauer, Rebecca, Mabrouk, Nesrine, Gadouas, Gauthier, Desaint, Corinne, Chevrier, Lucie, Lefebvre, Maeva, Radenne, Anne, Roelens, Marie, Parfait, Béatrice, Weiskopf, Daniela, Sette, Alessandro, Gruel, Nadège, Courbebaisse, Marie, Appay, Victor, Paul, Stephane, Gorochov, Guy, Ropers, Jacques, Lebbah, Said, Lelievre, Jean-Daniel, Johannes, Ludger, Ulmer, Jonathan, Lebeaux, David, Friedlander, Gerard, De Lamballerie, Xavier, Ravel, Patrice, Kieny, Marie Paule, Batteux, Fréderic, Durier, Christine, Launay, Odile, Tartour, Eric

“…Coordinating immune responses – humoral and cellular – is vital for protection against severe Covid-19. Our study evaluates a multicytokine CD4+T cell…”
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Decrease of Pro-Angiogenic Monocytes Predicts Clinical Response to Anti-Angiogenic Treatment in Patients with Metastatic Renal Cell Carcinoma by Oudard, Stephane, Benhamouda, Nadine, Escudier, Bernard, Ravel, Patrice, Tran, Thi, Levionnois, Emeline, Negrier, Sylvie, Barthelemy, Philippe, Berdah, Jean François, Gross-Goupil, Marine, Sternberg, Cora N, Bono, Petri, Porta, Camillo, De Giorgi, Ugo, Parikh, Omi, Hawkins, Robert, Highley, Martin, Wilke, Jochen, Decker, Thomas, Tanchot, Corinne, Gey, Alain, Terme, Magali, Tartour, Eric

“…The modulation of subpopulations of pro-angiogenic monocytes (VEGFR-1 CD14 and Tie2 CD14) was analyzed in an ancillary study from the prospective PazopanIb…”
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Valine/isoleucine variants drive selective pressure in the VP1 sequence of EV-A71 enteroviruses by Duy, Nghia Ngu, Huong, Le Thi Thanh, Ravel, Patrice, Huong, Le Thi Song, Dwivedi, Ankit, Sessions, October Michael, Hou, Yan'An, Chua, Robert, Kister, Guilhem, Afelt, Aneta, Moulia, Catherine, Gubler, Duane J, Thiem, Vu Dinh, Thanh, Nguyen Thi Hien, Devaux, Christian, Duong, Tran Nhu, Hien, Nguyen Tran, Cornillot, Emmanuel, Gavotte, Laurent, Frutos, Roger

“…In 2011-2012, Northern Vietnam experienced its first large scale hand foot and mouth disease (HFMD) epidemic. In 2011, a major HFMD epidemic was also reported…”
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Modular response analysis reformulated as a multilinear regression problem by Borg, Jean-Pierre, Colinge, Jacques, Ravel, Patrice

“…Abstract Motivation Modular response analysis (MRA) is a well-established method to infer biological networks from perturbation data. Classically, MRA requires…”
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PD-1―Expressing Tumor-Infiltrating T Cells Are a Favorable Prognostic Biomarker in HPV-Associated Head and Neck Cancer by BADOUAL, Cécile, HANS, Stéphane, GEY, Alain, ROTEM-YEHUDAR, Rinat, PERE, Hélène, TRAN, Thi, GUERIN, Coralie L, CHAUVAT, Anne, DRANSART, Estelle, ALANIO, Cécile, ALBERT, Sebastien, BARRY, Beatrix, MERILLON, Nathalie, SANDOVAL, Federico, QUINTIN-COLONNA, Françoise, BRUNEVALL, Patrick, FRIDMAN, Wolf H, LEMOINE, Francois M, OUDARD, Stephane, JOHANNES, Ludger, OLIVE, Daniel, BRASNU, Daniel, TARTOUR, Eric, VAN RYSWICK, Cordélia, RAVEL, Patrice, BENHAMOUDA, Nadine, LEVIONNOIS, Emeline, NIZARD, Mevyn, SI-MOHAMED, Ali, BESNIER, Nicolas

“…Head and neck cancers positive for human papillomavirus (HPV) have a more favorable clinical outcome than HPV-negative cancers, but it is unknown why this is…”
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Compaction behavior and deformation mechanism of directly compressible textured mannitol in a rotary tablet press simulator by Tarlier, Nicolas, Soulairol, Ian, Bataille, Bernard, Baylac, Gilles, Ravel, Patrice, Nofrerias, Isaac, Lefèvre, Philippe, Sharkawi, Tahmer

“…[Display omitted] Textured mannitol powder is widely used as a pharmaceutical excipient for tablet compaction. In order to choose the right tableting…”
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Plasma CD27, a Surrogate of the Intratumoral CD27-CD70 Interaction, Correlates with Immunotherapy Resistance in Renal Cell Carcinoma by Benhamouda, Nadine, Sam, Ikuan, Epaillard, Nicolas, Gey, Alain, Phan, Letuan, Pham, Hang Phuong, Gruel, Nadège, Saldmann, Antonin, Pineau, Joséphine, Hasan, Milena, Quiniou, Valentin, Nevoret, Camille, Verkarre, Virginie, Libri, Valentina, Mella, Sebastien, Granier, Clémence, Broudin, Chloe, Ravel, Patrice, De Guillebon, Eléonore, Mauge, Laetitia, Helley, Dominique, Jabla, Bernd, Chaput, Nathalie, Albiges, Laurence, Katsahian, Sandrine, Adam, Julien, Mejean, Arnaud, Adotevi, Olivier, Vano, Yann A, Oudard, Stéphane, Tartour, Eric

“…CD70 is a costimulatory molecule known to activate CD27-expressing T cells. CD27-CD70 interaction leads to the release of soluble CD27 (sCD27). Clear-cell…”
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A Decrease of Regulatory T Cells Correlates With Overall Survival After Sunitinib-based Antiangiogenic Therapy in Metastatic Renal Cancer Patients by ADOTEVI, Olivier, PERE, Helene, MEJEAN, Arnaud, FRIDMAN, Wolf H, OUDARD, Stephane, TARTOUR, Eric, RAVEL, Patrice, HAICHEUR, Nacilla, BADOUAL, Cecile, MERILLON, Nathalie, MEDIONI, Jacques, PEYRARD, Severine, RONCELIN, Stephane, VERKARRE, Virginie

“…Sunitinib, an antiangiogenic molecule, is one of the first-line standard of care in the treatment of patients with metastatic renal cell carcinoma. However, it…”
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A CCR4 antagonist combined with vaccines induces antigen-specific CD8+ T cells and tumor immunity against self antigens by Pere, Helene, Montier, Yves, Bayry, Jagadeesh, Quintin-Colonna, Francoise, Merillon, Nathalie, Dransart, Estelle, Badoual, Cecile, Gey, Alain, Ravel, Patrice, Marcheteau, Elie, Batteux, Frederic, Sandoval, Federico, Adotevi, Olivier, Chiu, Christopher, Garcia, Sylvie, Tanchot, Corinne, Lone, Yu-Chun, Ferreira, Luis Carlos, Nelson, Brad H., Hanahan, Douglas, Fridman, Wolf Herman, Johannes, Ludger, Tartour, Eric

“…Regulatory T cells (Tregs) may impede cancer vaccine efficacy in hematologic malignancies and cancer. CCR4 antagonists, an emergent class of Treg inhibitor,…”
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Rapalog combined with CCR4 antagonist improves anticancer vaccines efficacy by Beziaud, Laurent, Boullerot, Laura, Tran, Thi, Mansi, Laura, Marie‐Joseph, Elodie Lauret, Ravel, Patrice, Johannes, Ludger, Bayry, Jagadeesh, Tartour, Eric, Adotévi, Olivier

“…mTOR pathway inhibitors such as rapalogs represent a promising tool to induce functional memory CD8 T cells. In our study, we investigated the combination of…”
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Rapalogs Efficacy Relies on the Modulation of Antitumor T-cell Immunity by Beziaud, Laurent, Mansi, Laura, Ravel, Patrice, Marie-Joseph, Elodie Lauret, Laheurte, Caroline, Rangan, Laurie, Bonnefoy, Francis, Pallandre, Jean-René, Boullerot, Laura, Gamonet, Clémentine, Vrecko, Sindy, Queiroz, Lise, Maurina, Tristan, Mouillet, Guillaume, Hon, Thierry Nguyen Tan, Curtit, Elsa, Royer, Bernard, Gaugler, Béatrice, Bayry, Jagadeesh, Tartour, Eric, Thiery-Vuillemin, Antoine, Pivot, Xavier, Borg, Christophe, Godet, Yann, Adotévi, Olivier

“…The rapalogs everolimus and temsirolimus that inhibit mTOR signaling are used as antiproliferative drugs in several cancers. Here we investigated the influence…”
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