Search Results - "Ravasi, T."

Genomes of coral dinoflagellate symbionts highlight evolutionary adaptations conducive to a symbiotic lifestyle by Aranda, M., Li, Y., Liew, Y. J., Baumgarten, S., Simakov, O., Wilson, M. C., Piel, J., Ashoor, H., Bougouffa, S., Bajic, V. B., Ryu, T., Ravasi, T., Bayer, T., Micklem, G., Kim, H., Bhak, J., LaJeunesse, T. C., Voolstra, C. R.

“…Despite half a century of research, the biology of dinoflagellates remains enigmatic: they defy many functional and genetic traits attributed to typical…”
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Neuro-molecular characterization of fish cleaning interactions by Ramírez-Calero, S., Paula, J. R., Otjacques, E., Rosa, R., Ravasi, T., Schunter, C.

“…Coral reef fish exhibit a large variety of behaviours crucial for fitness and survival. The cleaner wrasse Labroides dimidiatus displays cognitive abilities…”
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Timing-specific parental effects of ocean warming in a coral reef fish by Bonzi, L C, Spinks, R K, Donelson, J M, Munday, P L, Ravasi, T, Schunter, C

“…Population and species persistence in a rapidly warming world will be determined by an organism's ability to acclimate to warmer conditions, especially across…”
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Neuromolecular responses in disrupted mutualistic cleaning interactions under future environmental conditions by Ramírez-Calero, S, Paula, J R, Otjacques, E, Ravasi, T, Rosa, R, Schunter, C

“…Mutualistic interactions, which constitute some of the most advantageous interactions among fish species, are highly vulnerable to environmental changes. A key…”
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Matching maternal and paternal experiences underpin molecular thermal acclimation by Bonzi, L C, Donelson, J M, Spinks, R K, Munday, P L, Ravasi, T, Schunter, C

“…The environment experienced by one generation has the potential to affect the subsequent one through non-genetic inheritance of parental effects. Since both…”
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Antisense Transcription in the Mammalian Transcriptome by Katayama, S, Tomaru, Y, Kasukawa, T, Waki, K, Nakanishi, M, Nakamura, M, Nishida, H, Yap, C. C, Suzuki, M, Kawai, J, Suzuki, H, Carninci, P, Hayashizaki, Y, Wells, C, Frith, M, Ravasi, T, Pang, K. C, Hallinan, J, Mattick, J, Hume, D. A, Lipovich, L, Batalov, S, Engström, P. G, Mizuno, Y, Faghihi, M. A, Sandelin, A, Chalk, A. M, Mottagui-Tabar, S, Liang, Z, Lenhard, B, Wahlestedt, C

“…Antisense transcription (transcription from the opposite strand to a protein-coding or sense strand) has been ascribed roles in gene regulation involving…”
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Integrated approaches to uncovering transcription regulatory networks in mammalian cells by Tan, Kai, Tegner, Jesper, Ravasi, Timothy

“…Integrative systems biology has emerged as an exciting research approach in molecular biology and functional genomics that involves the integration of…”
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Systems biology of innate immunity by Tegnér, Jesper, Nilsson, Roland, Bajic, Vladimir B., Björkegren, Johan, Ravasi, Timothy

“…Systems Biology has emerged as an exciting research approach in molecular biology and functional genomics that involves a systematic use of genomic, proteomic,…”
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Generation of Diversity in the Innate Immune System: Macrophage Heterogeneity Arises from Gene-Autonomous Transcriptional Probability of Individual Inducible Genes by Ravasi, Timothy, Wells, Christine, Forest, Alistair, Underhill, David M, Wainwright, Brandon J, Aderem, Alan, Grimmond, Sean, Hume, David A

“…Microbial products such as LPS stimulate macrophages to produce a wide diversity of inducible gene products needed for immediate host defense and priming of an…”
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Induction of Nramp2 in activated mouse macrophages is dissociated from regulation of the Nramp1, classical inflammatory genes, and genes involved in iron metabolism by Wardrop, S. L., Wells, C., Ravasi, T., Hume, D. A., Richardson, D. R.

“…Nramp2 is a widely expressed metal‐ion transporter that is involved in dietary iron absorption in the duodenum and iron uptake from transferrin in peripheral…”
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Interferon-γ: an overview of signals, mechanisms and functions by Schroder, Kate, Hertzog, Paul J., Ravasi, Timothy, Hume, David A.

“…Interferon‐γ (IFN‐γ) coordinates a diverse array of cellular programs through transcriptional regulation of immunologically relevant genes. This article…”
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An Atlas of Combinatorial Transcriptional Regulation in Mouse and Man by Ravasi, Timothy, Suzuki, Harukazu, Cannistraci, Carlo Vittorio, Katayama, Shintaro, Bajic, Vladimir B., Tan, Kai, Akalin, Altuna, Schmeier, Sebastian, Kanamori-Katayama, Mutsumi, Bertin, Nicolas, Carninci, Piero, Daub, Carsten O., Forrest, Alistair R.R., Gough, Julian, Grimmond, Sean, Han, Jung-Hoon, Hashimoto, Takehiro, Hide, Winston, Hofmann, Oliver, Kamburov, Atanas, Kaur, Mandeep, Kawaji, Hideya, Kubosaki, Atsutaka, Lassmann, Timo, van Nimwegen, Erik, MacPherson, Cameron Ross, Ogawa, Chihiro, Radovanovic, Aleksandar, Schwartz, Ariel, Teasdale, Rohan D., Tegnér, Jesper, Lenhard, Boris, Teichmann, Sarah A., Arakawa, Takahiro, Ninomiya, Noriko, Murakami, Kayoko, Tagami, Michihira, Fukuda, Shiro, Imamura, Kengo, Kai, Chikatoshi, Ishihara, Ryoko, Kitazume, Yayoi, Kawai, Jun, Hume, David A., Ideker, Trey, Hayashizaki, Yoshihide

“…Combinatorial interactions among transcription factors are critical to directing tissue-specific gene expression. To build a global atlas of these…”
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Non-chemotoxic induction of cancer cell death using magnetic nanowires by Contreras, Maria F, Sougrat, Rachid, Zaher, Amir, Ravasi, Timothy, Kosel, Jürgen

“…In this paper, we show that magnetic nanowires with weak magnetic fields and low frequencies can induce cell death via a mechanism that does not involve heat…”
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The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line by Suzuki, Harukazu, Forrest, Alistair R R, van Nimwegen, Erik, Daub, Carsten O, Balwierz, Piotr J, Irvine, Katharine M, Lassmann, Timo, Ravasi, Timothy, Hasegawa, Yuki, de Hoon, Michiel J L, Katayama, Shintaro, Schroder, Kate, Carninci, Piero, Tomaru, Yasuhiro, Kanamori-Katayama, Mutsumi, Kubosaki, Atsutaka, Akalin, Altuna, Ando, Yoshinari, Arner, Erik, Asada, Maki, Asahara, Hiroshi, Bailey, Timothy, Bajic, Vladimir B, Bauer, Denis, Beckhouse, Anthony G, Bertin, Nicolas, Björkegren, Johan, Brombacher, Frank, Bulger, Erika, Chalk, Alistair M, Chiba, Joe, Cloonan, Nicole, Dawe, Adam, Dostie, Josee, Engström, Pär G, Essack, Magbubah, Faulkner, Geoffrey J, Fink, J Lynn, Fredman, David, Fujimori, Ko, Furuno, Masaaki, Gojobori, Takashi, Gough, Julian, Grimmond, Sean M, Gustafsson, Mika, Hashimoto, Megumi, Hashimoto, Takehiro, Hatakeyama, Mariko, Heinzel, Susanne, Hide, Winston, Hofmann, Oliver, Hörnquist, Michael, Huminiecki, Lukasz, Ikeo, Kazuho, Imamoto, Naoko, Inoue, Satoshi, Inoue, Yusuke, Ishihara, Ryoko, Iwayanagi, Takao, Jacobsen, Anders, Kaur, Mandeep, Kawaji, Hideya, Kerr, Markus C, Kimura, Ryuichiro, Kimura, Syuhei, Kimura, Yasumasa, Kitano, Hiroaki, Koga, Hisashi, Kojima, Toshio, Kondo, Shinji, Konno, Takeshi, Krogh, Anders, Kruger, Adele, Kumar, Ajit, Lenhard, Boris, Lennartsson, Andreas, Lindow, Morten, Lizio, Marina, Macpherson, Cameron, Maeda, Norihiro, Maher, Christopher A, Maqungo, Monique, Mar, Jessica, Matigian, Nicholas A, Matsuda, Hideo, Mattick, John S, Meier, Stuart, Miyamoto, Sei, Miyamoto-Sato, Etsuko, Nakabayashi, Kazuhiko, Nakachi, Yutaka, Nakano, Mika, Nygaard, Sanne, Okayama, Toshitsugu, Okazaki, Yasushi, Okuda-Yabukami, Haruka, Orlando, Valerio, Otomo, Jun, Pachkov, Mikhail, Petrovsky, Nikolai

“…The FANTOM4 study identified transcriptional start sites active during proliferation arrest and differentiation of the human monocytic cell line THP-1…”
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Genome-wide analysis of mammalian promoter architecture and evolution by Hume, David A, Hayashizaki, Yoshihide, Carninci, Piero, Sandelin, Albin, Lenhard, Boris, Katayama, Shintaro, Shimokawa, Kazuro, Ponjavic, Jasmina, Semple, Colin A M, Taylor, Martin S, Engström, Pär G, Frith, Martin C, Forrest, Alistair R R, Alkema, Wynand B, Tan, Sin Lam, Plessy, Charles, Kodzius, Rimantas, Ravasi, Timothy, Kasukawa, Takeya, Fukuda, Shiro, Kanamori-Katayama, Mutsumi, Kitazume, Yayoi, Kawaji, Hideya, Kai, Chikatoshi, Nakamura, Mari, Konno, Hideaki, Nakano, Kenji, Mottagui-Tabar, Salim, Arner, Peter, Chesi, Alessandra, Gustincich, Stefano, Persichetti, Francesca, Suzuki, Harukazu, Grimmond, Sean M, Wells, Christine A, Orlando, Valerio, Wahlestedt, Claes, Liu, Edison T, Harbers, Matthias, Kawai, Jun, Bajic, Vladimir B

“…Mammalian promoters can be separated into two classes, conserved TATA box-enriched promoters, which initiate at a well-defined site, and more plastic, broad…”
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Experimental validation of the regulated expression of large numbers of non-coding RNAs from the mouse genome by Ravasi, Timothy, Suzuki, Harukazu, Pang, Ken C, Katayama, Shintaro, Furuno, Masaaki, Okunishi, Rie, Fukuda, Shiro, Ru, Kelin, Frith, Martin C, Gongora, M Milena, Grimmond, Sean M, Hume, David A, Hayashizaki, Yoshihide, Mattick, John S

“…Recent large-scale analyses of mainly full-length cDNA libraries generated from a variety of mouse tissues indicated that almost half of all representative…”
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Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs by Okazaki, Y, Furuno, M, Kasukawa, T, Adachi, J, Bono, H, Kondo, S, Nikaido, I, Osato, N, Saito, R, Suzuki, H, Yamanaka, I, Kiyosawa, H, Yagi, K, Tomaru, Y, Hasegawa, Y, Nogami, A, Schönbach, C, Gojobori, T, Baldarelli, R, Hill, D P, Bult, C, Hume, D A, Quackenbush, J, Schriml, L M, Kanapin, A, Matsuda, H, Batalov, S, Beisel, K W, Blake, J A, Bradt, D, Brusic, V, Chothia, C, Corbani, L E, Cousins, S, Dalla, E, Dragani, T A, Fletcher, C F, Forrest, A, Frazer, K S, Gaasterland, T, Gariboldi, M, Gissi, C, Godzik, A, Gough, J, Grimmond, S, Gustincich, S, Hirokawa, N, Jackson, I J, Jarvis, E D, Kanai, A, Kawaji, H, Kawasawa, Y, Kedzierski, R M, King, B L, Konagaya, A, Kurochkin, I V, Lee, Y, Lenhard, B, Lyons, P A, Maglott, D R, Maltais, L, Marchionni, L, McKenzie, L, Miki, H, Nagashima, T, Numata, K, Okido, T, Pavan, W J, Pertea, G, Pesole, G, Petrovsky, N, Pillai, R, Pontius, J U, Qi, D, Ramachandran, S, Ravasi, T, Reed, J C, Reed, D J, Reid, J, Ring, B Z, Ringwald, M, Sandelin, A, Schneider, C, Semple, C A M, Setou, M, Shimada, K, Sultana, R, Takenaka, Y, Taylor, M S, Teasdale, R D, Tomita, M, Verardo, R, Wagner, L, Wahlestedt, C, Wang, Y, Watanabe, Y, Wells, C, Wilming, L G, Wynshaw-Boris, A, Yanagisawa, M

“…Only a small proportion of the mouse genome is transcribed into mature messenger RNA transcripts. There is an international collaborative effort to identify…”
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Identification and Predictive Value of Interleukin-6+ Interleukin-10+ and Interleukin-6− Interleukin-10+ Cytokine Patterns in ST-Elevation Acute Myocardial Infarction by Ammirati, Enrico, Cannistraci, Carlo V, Cristell, Nicole A, Vecchio, Viviana, Palini, Alessio G, Tornvall, Per, Paganoni, Anna M, Miendlarzewska, Ewa A, Sangalli, Laura M, Monello, Alberto, Pernow, John, Björnstedt Bennermo, Marie, Marenzi, Giancarlo, Hu, Dayi, Uren, Neal G, Cianflone, Domenico, Ravasi, Timothy, Manfredi, Angelo A, Maseri, Attilio

“…RATIONALE:At the onset of ST-elevation acute myocardial infarction (STEMI), patients can present with very high circulating interleukin-6 (IL-6) levels or very…”
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Mouse neutrophilic granulocytes express mRNA encoding the macrophage colony-stimulating factor receptor (CSF-1R) as well as many other macrophage-specific transcripts and can transdifferentiate into macrophages in vitro in response to CSF-1 by Sasmono, R. Tedjo, Ehrnsperger, Achim, Cronau, Stephen L., Ravasi, Timothy, Kandane, Rangi, Hickey, Michael J., Cook, Andrew D., Himes, S. Roy, Hamilton, John A., Hume, David A.

“…The differentiation of macrophages from their progenitors is controlled by macrophage colony‐stimulating factor (CSF‐1), which binds to a receptor (CSF‐1R)…”
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The mononuclear phagocyte system revisited by Hume, David A., Ross, Ian L., Himes, S. Roy, Sasmono, R. Tedjo, Wells, Christine A., Ravasi, Timothy

“…The mononuclear phagocyte system (MPS) was defined as a family of cells comprising bone marrow progenitors, blood monocytes, and tissue macrophages. In this…”
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