Search Results - "Ravasi, Saula"

CysLT₁ receptor is a target for extracellular nucleotide-induced heterologous desensitization: a possible feedback mechanism in inflammation by Capra, Valérie, Ravasi, Saula, Accomazzo, Maria Rosa, Citro, Simona, Grimoldi, Monica, Abbracchio, Maria P, Rovati, G. Enrico

“…Both cysteinyl-leukotrienes and extracellular nucleotides mediate inflammatory responses via specific G-protein-coupled receptors, the CysLT and the P2Y…”
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CysLT1 signal transduction in differentiated U937 cells involves the activation of the small GTP-binding protein Ras by CAPRA, Valérie, RAVASI, Saula, ACCOMAZZO, Maria Rosa, PARENTI, Marco, ROVATI, G. Enrico

“…We investigated the signal transduction pathway(s) of leukotriene D(4) (LTD(4)) in the human promonocytic U937 cells, a cell line known to constitutively…”
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Thromboxane Prostanoid Receptor Signals Through Gi Protein to Rapidly Activate Extracellular Signal-Regulated Kinase in Human Airways by Citro, Simona, Ravasi, Saula, Rovati, G. Enrico, Capra, Valerie

“…We showed previously that activation of the thromboxane prostanoid (TP) receptor causes human airway smooth muscle (HASM) cells to proliferate, suggesting a…”
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Cysteinyl-leukotrienes in the regulation of β2-adrenoceptor function: an in vitro model of asthma by Rovati, G Enrico, Baroffio, Michele, Citro, Simona, Brichetto, Lorenzo, Ravasi, Saula, Milanese, Manlio, Crimi, Emanuele, Brusasco, Vito

“…BACKGROUND: The response to β2-adrenoceptor agonists is reduced in asthmatic airways. This desensitization may be in part due to inflammatory mediators and may…”
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CysLT1 receptor-induced human airway smooth muscle cells proliferation requires ROS generation, EGF receptor transactivation and ERK1/2 phosphorylation by Ravasi, Saula, Citro, Simona, Viviani, Barbara, Capra, Valérie, Rovati, G Enrico

“…Cysteine-containing leukotrienes (cysteinyl-LTs) are pivotal inflammatory mediators that play important roles in the pathophysiology of asthma, allergic…”
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Selectivity of Recombinant Human Leukotriene D4, Leukotriene B4, and Lipoxin A4 Receptors with Aspirin-Triggered 15-epi-LXA4 and Regulation of Vascular and Inflammatory Responses by Gronert, Karsten, Martinsson-Niskanen, Titti, Ravasi, Saula, Chiang, Nan, Serhan, Charles N

“…Aspirin-triggered lipoxin A 4 (ATL, 15-epi-LXA 4 ) and leukotriene D 4 (LTD 4 ) possess opposing vascular actions mediated via receptors distinct from the LXA…”
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Pharmacological differences among CysLT1 receptor antagonists with respect to LTC4 and LTD4 in human lung parenchyma by RAVASI, Saula, CAPRA, Valérie, PANIGALLI, Tiziana, ROVATI, G. Enrico, NICOSIA, Simonetta

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Thromboxane Prostanoid Receptor Signals Through G^sub i^ Protein to Rapidly Activate Extracellular Signal-Regulated Kinase in Human Airways by Citro, Simona, Ravasi, Saula, Rovati, G Enrico, Capra, Valérie

“…We showed previously that activation of the thromboxane prostanoid (TP) receptor causes human airway smooth muscle (HASM) cells to proliferate, suggesting a…”
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Thromboxane Prostanoid Receptor Signals Through G i Protein to Rapidly Activate Extracellular Signal–Regulated Kinase in Human Airways by Citro, Simona, Ravasi, Saula, Rovati, G. Enrico, Capra, Valérie

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CysLT sub(1) receptor is a target for extracellular nucleotide-induced heterologous desensitization: a possible feedback mechanism in inflammation by Capra, Valerie, Ravasi, Saula, Accomazzo, Maria Rosa, Citro, Simona, Grimoldi, Monica, Abbracchio, Maria P, Rovati, GEnrico

“…Both cysteinyl-leukotrienes and extracellular nucleotides mediate inflammatory responses via specific G-protein-coupled receptors, the CysLT and the P2Y…”
Get full text

Thromboxane prostanoid receptor in human airway smooth muscle cells: a relevant role in proliferation by Capra, Valérie, Habib, Aı̈da, Accomazzo, Maria Rosa, Ravasi, Saula, Citro, Simona, Levy-Toledano, Sylviane, Nicosia, Simonetta, Rovati, G.Enrico

“…Thromboxane A 2 has been implicated as a mediator of bronchial hyperresponsiveness in asthma. Modulating agents are currently marketed in Japan and under…”
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Effect of endogenous and exogenous prostaglandin E2 on interleukin-1β-induced cyclooxygenase-2 expression in human airway smooth-muscle cells by BONAZZI, Albino, BOLLA, Manlio, CHIESA, Giuseppe, FOLCO, Giancarlo, SALA, Angelo, BUCCELLATI, Carola, HERNANDEZ, Alicia, ZARINI, Simona, VIGANO, Teresa, FUMAGALLI, Francesca, VIAPPIANI, Serena, RAVASI, Saula, ZANNINI, Piero

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Cysteinyl-leukotrienes in the regulation of [beta]2-adrenoceptor function: an in vitro model of asthma by Rovati, G Enrico, Baroffio, Michele, Citro, Simona, Brichetto, Lorenzo, Ravasi, Saula, Milanese, Manlio, Crimi, Emanuele, Brusasco, Vito

“…Background The response to [beta].sub.2-adrenoceptor agonists is reduced in asthmatic airways. This desensitization may be in part due to inflammatory…”
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CysLT 1 signal transduction in differentiated U937 cells involves the activation of the small GTP-binding protein Ras by Capra, Valérie, Ravasi, Saula, Accomazzo, Maria Rosa, Parenti, Marco, Rovati, G.Enrico

“…We investigated the signal transduction pathway(s) of leukotriene D 4 (LTD 4) in the human promonocytic U937 cells, a cell line known to constitutively express…”
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Involvement of prenylated proteins in calcium signaling induced by LTD4 in differentiated U937 cells by Capra, Valérie, Accomazzo, Maria Rosa, Ravasi, Saula, Parenti, Marco, Macchia, Marco, Nicosia, Simonetta, Rovati, G Enrico

“…We investigated signal transduction pathways for LTD4 in the human promonocytic cell line U937 known, upon differentiation, to express CysLT1 receptors. We…”
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Pharmacological differences among CysLT 1 receptor antagonists with respect to LTC 4 and LTD 4 in human lung parenchyma by Ravasi, Saula, Capra, Valérie, Panigalli, Tiziana, Rovati, G.Enrico, Nicosia, Simonetta

“…We have previously reported, by means of equilibrium binding studies, the existence of two distinct binding sites with receptor characteristics for LTC 4 and…”
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Effect of Endogenous and Exogenous Prostaglandin E 2 on Interleukin-1 β –Induced Cyclooxygenase-2 Expression in Human Airway Smooth-Muscle Cells by BONAZZI, ALBINO, BOLLA, MANLIO, BUCCELLATI, CAROLA, HERNANDEZ, ALICIA, ZARINI, SIMONA, VIGANÒ, TERESA, FUMAGALLI, FRANCESCA, VIAPPIANI, SERENA, RAVASI, SAULA, ZANNINI, PIERO, CHIESA, GIUSEPPE, FOLCO, GIANCARLO, SALA, ANGELO

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Pharmacological differences among CysLT(1) receptor antagonists with respect to LTC(4) and LTD(4) in human lung parenchyma by Ravasi, Saula, Capra, Valérie, Panigalli, Tiziana, Rovati, G Enrico, Nicosia, Simonetta

“…We have previously reported, by means of equilibrium binding studies, the existence of two distinct binding sites with receptor characteristics for LTC(4) and…”
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Selectivity of recombinant human leukotriene D4, leukotriene B4, and lipoxin A4 receptors with aspirin-triggered 15-epi-LXA4 and regulation of vascular and inflammatory by Gronert, Karsten, Martinsson-Niskanen, Titti, Ravasi, Saula, Chiang, Nan, Serhan, Charles N

“…Aspirin-triggered lipoxin A(4) (ATL, 15-epi-LXA(4)) and leukotriene D(4) (LTD(4)) possess opposing vascular actions mediated via receptors distinct from the…”
Get full text

Selectivity of Recombinant Human Leukotriene D 4, Leukotriene B 4, and Lipoxin A 4 Receptors with Aspirin-Triggered 15-epi-LXA 4 and Regulation of Vascular and Inflammatory Responses by Gronert, Karsten, Martinsson-Niskanen, Titti, Ravasi, Saula, Chiang, Nan, Serhan, Charles N.

“…Aspirin-triggered lipoxin A 4 (ATL, 15-epi-LXA 4) and leukotriene D 4(LTD 4) possess opposing vascular actions mediated via receptors distinct from the LXA 4…”
Get full text