Search Results - "Raval, Kavit"
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Nanoemulsion: Concepts, development and applications in drug delivery
Published in Journal of controlled release (28-04-2017)“…Nanoemulsions are biphasic dispersion of two immiscible liquids: either water in oil (W/O) or oil in water (O/W) droplets stabilized by an amphiphilic…”
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2
Targeting tumor associated macrophages (TAMs) via nanocarriers
Published in Journal of controlled release (28-05-2017)“…Recruitment of inflammatory cells to tumor has been well documented, with the most frequent inhabitants being macrophages termed as tumor associated…”
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3
Improved chemotherapy against breast cancer through immunotherapeutic activity of fucoidan decorated electrostatically assembled nanoparticles bearing doxorubicin
Published in International journal of biological macromolecules (01-02-2019)“…Immunotherapeutic nanoparticles (NPs) could be a viable option for delivering cytotoxic agents in a manner which suppresses their toxic manifestations…”
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Poly-L-lysine Coated Oral Nanoemulsion for Combined Delivery of Insulin and C-Peptide
Published in Journal of pharmaceutical sciences (01-12-2022)“…An attempt of co-delivery of insulin and C-peptide enclosed in linseed oil globules has been made employing a protective coating of positively charged…”
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Chitosan coated PluronicF127 micelles for effective delivery of Amphotericin B in experimental visceral leishmaniasis
Published in International journal of biological macromolecules (01-12-2017)“…The goal of study was to develop micellar formulation of Amphotericin B (AmB) to improve its antileishmanial efficacy. AmB loaded pluronic F127 (PF 127)…”
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Fabrication of 3-O-sn-Phosphatidyl-L-serine Anchored PLGA Nanoparticle Bearing Amphotericin B for Macrophage Targeting
Published in Pharmaceutical research (01-03-2018)“…ABSTRACT Purpose To fabricate, characterize and evaluate 3-O-sn-Phosphatidyl-L-serine (PhoS) anchored PLGA nanoparticles for macrophage targeted therapeutic…”
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Dysfunctional β-cell longevity in diabetes relies on energy conservation and positive epistasis
Published in Life science alliance (01-12-2024)“…Long-lived PFKFB3-expressing β-cells are dysfunctional partly because of prevailing glycolysis that compromises metabolic coupling of insulin secretion. Their…”
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Click Biotinylation of PLGA Template for Biotin Receptor Oriented Delivery of Doxorubicin Hydrochloride in 4T1 Cell-Induced Breast Cancer
Published in Molecular pharmaceutics (07-08-2017)“…PLGA was functionalized with PEG and biotin using click chemistry to generate a biotin receptor targeted copolymer (biotinylated–PEG-PLGA) which in turn was…”
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Doxorubicin Hydrochloride Loaded Zymosan-Polyethylenimine Biopolymeric Nanoparticles for Dual ‘Chemoimmunotherapeutic’ Intervention in Breast Cancer
Published in Pharmaceutical research (01-09-2017)“…Objective To utilize nanoparticles produced by condensation of zymosan (an immunotherapeutic polysaccharide) with pegylated polyethylenimine (PEG-PEI) for dual…”
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Bridging small interfering RNA with giant therapeutic outcomes using nanometric liposomes
Published in Journal of controlled release (28-12-2015)“…The scope of RNAi based therapeutics is unquestionable. However, if we dissect the current trend of clinical trials for afore mentioned drug class, some stark…”
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Nanosized complexation assemblies housed inside reverse micelles churn out monocytic delivery cores for bendamustine hydrochloride
Published in European journal of pharmaceutics and biopharmaceutics (01-04-2017)“…[Display omitted] We explore a plausible method of targeting bendamustine hydrochloride (BM) to circulatory monocytes by exploiting their intrinsic…”
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Novel Validated RP-HPLC Method for Bendamustine Hydrochloride Based on Ion-pair Chromatography: Application in Determining Infusion Stability and Pharmacokinetics
Published in Journal of chromatographic science (01-01-2017)“…Ion pair chromatography was used for quantifying bendamustine hydrochloride (BH) in its marketed vial. The permissive objective was to investigate time…”
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