Search Results - "Raux, E"

Biosynthesis of cobalamin (vitamin B12): a bacterial conundrum by Raux, E, Schubert, H L, Warren, M J

“…The biosynthesis of cobalamin (vitamin B12) is described, revealing how the concerted action of around 30 enzyme-mediated steps results in the synthesis of one…”
Get full text

Cobalamin (vitamin B12) biosynthesis: identification and characterization of a Bacillus megaterium cobI operon by Raux, E, Lanois, A, Warren, M J, Rambach, A, Thermes, C

“…A 16 kb DNA fragment has been isolated from a Bacillus megaterium genomic library and fully sequenced. The fragment contains 15 open reading frames, 14 of…”
Get full text

Salmonella typhimurium cobalamin (vitamin B12) biosynthetic genes: functional studies in S. typhimurium and Escherichia coli by Raux, E, Lanois, A, Levillayer, F, Warren, M J, Brody, E, Rambach, A, Thermes, C

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

A role for Salmonella typhimurium cbiK in cobalamin (vitamin B12) and siroheme biosynthesis by Raux, E, Thermes, C, Heathcote, P, Rambach, A, Warren, M J

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Structural diversity in metal ion chelation and the structure of uroporphyrinogen III synthase by Schubert, H L, Raux, E, Matthews, M A A, Phillips, J D, Wilson, K S, Hill, C P, Warren, M J

“…All tetrapyrroles are synthesized through a branched pathway, and although each tetrapyrrole receives unique modifications around the ring periphery, they all…”
Get more information

The biosynthesis of adenosylcobalamin (vitamin B12) by Warren, Martin J, Raux, Evelyne, Schubert, Heidi L, Escalante-Semerena, Jorge C

“…Vitamin B12, or cobalamin, is one of the most structurally complex small molecules made in Nature. Major progress has been made over the past decade in…”
Get more information

Optimization of Met8p crystals through protein-storage buffer manipulation by Schubert, Heidi L., Raux, Evelyne, Warren, Martin J., Wilson, Keith S.

“…Sirohaem, the prosthetic group of assimilatory sulfite and nitrite reductases, is a modified tetrapyrrole that belongs to the same fraternity of…”
Get full text

Production of cobalamin and sirohaem in Bacillus megaterium: an investigation into the role of the branchpoint chelatases sirohydrochlorin ferrochelatase (SirB) and sirohydrochlorin cobalt chelatase (CbiX) by Leech, H K, Raux-Deery, E, Heathcote, P, Warren, M J

“…One of the four operons required for cobalamin biosynthesis in Bacillus megaterium is also associated with sirohaem synthesis, and contains three genes, sirA,…”
Get more information

A story of chelatase evolution: identification and characterization of a small 13-15-kDa "ancestral" cobaltochelatase (CbiXS) in the archaea by Brindley, Amanda A, Raux, Evelyne, Leech, Helen K, Schubert, Heidi L, Warren, Martin J

“…The cobaltochelatase required for the synthesis of vitamin B12 (cobalamin) in the archaeal kingdom has been identified as CbiX through similarity searching…”
Get full text

Algae acquire vitamin B 12 through a symbiotic relationship with bacteria by Smith, Alison G, Croft, Martin T, Lawrence, Andrew D, Raux-Deery, Evelyne, Warren, Martin J

“…Vitamin B12 (cobalamin) was identified nearly 80 years ago as the anti-pernicious anaemia factor in liver, and its importance in human health and disease has…”
Get full text

The structure of Saccharomyces cerevisiae Met8p, a bifunctional dehydrogenase and ferrochelatase by Schubert, Heidi L., Raux, Evelyne, Brindley, Amanda A., Leech, Helen K., Wilson, Keith S., Hill, Christopher P., Warren, Martin J.

“…Sirohaem is a tetrapyrrole‐derived prosthetic group that is required for the essential assimilation of sulfur and nitrogen into all living systems as part of…”
Get full text

Algae acquire vitamin B12 through a symbiotic relationship with bacteria by Croft, M.T, Lawrence, A.D, Raux-Deery, E, Warren, M.J, Smith, A.G

“…Vitamin B12 (cobalamin) was identified nearly 80 years ago as the anti-pernicious anaemia factor in liver, and its importance in human health and disease has…”
Get full text

Identification and functional analysis of enzymes required for precorrin-2 dehydrogenation and metal ion insertion in the biosynthesis of sirohaem and cobalamin in Bacillus megaterium by Raux, Evelyne, Leech, Helen K, Beck, Richard, Schubert, Heidi L, Santander, Patricio J, Roessner, Charles A, Scott, A Ian, Martens, Jan H, Jahn, Dieter, Thermes, Claude, Rambach, Alain, Warren, Martin J

“…In Bacillus megaterium, the hemAXBCDL genes were isolated and were found to be highly similar to the genes from Bacillus subtilis that are required for the…”
Get full text

Structure/Function Studies on a S-Adenosyl- l-methionine-dependent Uroporphyrinogen III C Methyltransferase (SUMT), a Key Regulatory Enzyme of Tetrapyrrole Biosynthesis by Vévodová, Jitka, Graham, Ross M., Raux, Evelyne, Schubert, Heidi L., Roper, David I., Brindley, Amanda A., Ian Scott, A., Roessner, Charles A., Stamford, N. Patrick J., Elizabeth Stroupe, M., Getzoff, Elizabeth D., Warren, Martin J., Wilson, Keith S.

“…The crystallographic structure of the Pseudomonas denitrificans S-adenosyl- l-methionine-dependent uroporphyrinogen III methyltransferase (SUMT), which is…”
Get full text

Biotin Synthase Mechanism:  Mutagenesis of the YNHNLD Conserved Motif by Lotierzo, Manuela, Raux, Evelyne, Tse Sum Bui, Bernadette, Goasdoue, Nicole, Libot, Francine, Florentin, Dominique, Warren, Martin J, Marquet, Andrée

“…Biotin synthase, a member of the “radical SAM” family, catalyzes the final step of the biotin biosynthetic pathway, namely, the insertion of a sulfur atom into…”
Get full text

Common Chelatase Design in the Branched Tetrapyrrole Pathways of Heme and Anaerobic Cobalamin Synthesis by Schubert, Heidi L, Raux, Evelyne, Wilson, Keith S, Warren, Martin J

“…Prosthetic groups such as heme, chlorophyll, and cobalamin (vitamin B12) are characterized by their branched biosynthetic pathway and unique metal insertion…”
Get full text

Isolation and characterization of 14 additional genes specifying the anaerobic biosynthesis of cobalamin (vitamin B12) in Propionibacterium freudenreichii (P. shermanii) by Roessner, Charles A, Huang, Ke-xue, Warren, Martin J, Raux, Evelyne, Scott, A. Ian

“…Center for Biological NMR, Department of Chemistry, Texas A&M University, College Station, TX 77843-3255, USA 1 School of Biological Sciences, Queen Mary,…”
Get full text

The enigma of cobalamin (Vitamin B12) biosynthesis in Porphyromonas gingivalis. Identification and characterization of a functional corrin pathway by Roper, J M, Raux, E, Brindley, A A, Schubert, H L, Gharbia, S E, Shah, H N, Warren, M J

“…The ability of Porphyromonas gingivalis to biosynthesize tetrapyrroles de novo has been investigated. Extracts of the bacterium do not possess activity for 5-…”
Get full text

role of Saccharomyces cerevisiae Met1p and Met8p in sirohaem and cobalamin biosynthesis by Raux, E, McVeigh, T, Peters, S.E, Leustek, T, Warren, M.J

“…MET1 and MET8 mutants of Saccharomyces cerevisiae can be complemented by Salmonella typhimurium cysG, indicating that the genes are involved in the…”
Get full text

Cobalamin (vitamin B12) biosynthesis: functional characterization of the Bacillus megaterium cbi genes required to convert uroporphyrinogen III into cobyrinic acid a,c-diamide by Raux, E, Lanois, A, Rambach, A, Warren, M J, Thermes, C

“…The function of individual genes of the Bacillus megaterium cobI operon genes in cobalamin (vitamin B12) biosynthesis was investigated by their ability to…”
Get full text