Search Results - "Rauter, Amélia P."

In vitro antioxidant and anti-inflammatory properties of Limonium algarvense flowers’ infusions and decoctions: A comparison with green tea (Camellia sinensis) by Rodrigues, Maria João, Neves, Vanessa, Martins, Alice, Rauter, Amélia P., Neng, Nuno R., Nogueira, José M.F., Varela, João, Barreira, Luísa, Custódio, Luísa

“…•Limonium algarvense flowers and green tea had similar antioxidant properties.•L. algarvense had higher iron chelating potential than green tea.•L. algarvense…”
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Targeting Type 2 Diabetes with C‑Glucosyl Dihydrochalcones as Selective Sodium Glucose Co-Transporter 2 (SGLT2) Inhibitors: Synthesis and Biological Evaluation by Jesus, Ana R, Vila-Viçosa, Diogo, Machuqueiro, Miguel, Marques, Ana P, Dore, Timothy M, Rauter, Amélia P

“…Inhibiting glucose reabsorption by sodium glucose co-transporter proteins (SGLTs) in the kidneys is a relatively new strategy for treating type 2 diabetes…”
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Alkyl deoxyglycoside-polymyxin combinations against critical priority carbapenem-resistant gram-negative bacteria by de Matos, Ana M., Calado, Patrícia, Miranda, Mónica, Almeida, Rita, Rauter, Amélia P., Oliveira, M. Conceição, Manageiro, Vera, Caniça, Manuela

“…The escalating antimicrobial resistance crisis urges the development of new antibacterial treatments with innovative mechanisms of action, particularly against…”
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C-Glucosylation as a tool for the prevention of PAINS-induced membrane dipole potential alterations by de Matos, Ana Marta, Blázquez-Sánchez, Maria Teresa, Sousa, Carla, Oliveira, Maria Conceição, de Almeida, Rodrigo F. M., Rauter, Amélia P.

“…The concept of Pan-Assay Interference Compounds (PAINS) is regarded as a threat to the recognition of the broad bioactivity of natural products. Based on the…”
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Sugar-based bactericides targeting phosphatidylethanolamine-enriched membranes by Dias, Catarina, Pais, João P., Nunes, Rafael, Blázquez-Sánchez, Maria-Teresa, Marquês, Joaquim T., Almeida, Andreia F., Serra, Patrícia, Xavier, Nuno M., Vila-Viçosa, Diogo, Machuqueiro, Miguel, Viana, Ana S., Martins, Alice, Santos, Maria S., Pelerito, Ana, Dias, Ricardo, Tenreiro, Rogério, Oliveira, Maria C., Contino, Marialessandra, Colabufo, Nicola A., de Almeida, Rodrigo F. M., Rauter, Amélia P.

“…Anthrax is an infectious disease caused by Bacillus anthracis , a bioterrorism agent that develops resistance to clinically used antibiotics. Therefore,…”
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Wittig Reaction: Domino Olefination and Stereoselectivity DFT Study. Synthesis of the Miharamycins’ Bicyclic Sugar Moiety by Cachatra, Vasco, Almeida, Andreia, Sardinha, João, Lucas, Susana D, Gomes, Ana, Vaz, Pedro D, Florêncio, M. Helena, Nunes, Rafael, Vila-Viçosa, Diogo, Calhorda, Maria José, Rauter, Amélia P

“…2-O-Acyl protected-d-ribo-3-uloses reacted with [(ethoxycarbonyl)­methylene]­triphenylphosphorane in acetonitrile to afford regio- and stereoselectively…”
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Exploiting the Therapeutic Potential of 8‑β‑d‑Glucopyranosylgenistein: Synthesis, Antidiabetic Activity, and Molecular Interaction with Islet Amyloid Polypeptide and Amyloid β‑Peptide (1–42) by Jesus, Ana R, Dias, Catarina, Matos, Ana M, de Almeida, Rodrigo F. M, Viana, Ana S, Marcelo, Filipa, Ribeiro, Rogério T, Macedo, Maria P, Airoldi, Cristina, Nicotra, Francesco, Martins, Alice, Cabrita, Eurico J, Jiménez-Barbero, Jesús, Rauter, Amélia P

“…8-β-d-Glucopyranosylgenistein (1), the major component of Genista tenera, was synthesized and showed an extensive therapeutical impact in the treatment of…”
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Phytochemical Profile and Anticholinesterase and Antimicrobial Activities of Supercritical versus Conventional Extracts of Satureja montana by Silva, Filipa V. M, Martins, Alice, Salta, Joana, Neng, Nuno R, Nogueira, José M. F, Mira, Delfina, Gaspar, Natália, Justino, Jorge, Grosso, Clara, Urieta, José S, Palavra, António M. S, Rauter, Amélia P

“…Winter savory Satureja montana is a medicinal herb used in traditional gastronomy for seasoning meats and salads. This study reports a comparison between…”
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Quantification of Hydrolytic Sugars from Eucalyptus globulus Bio-Oil Aqueous Solution after Thermochemical Liquefaction by Luciana Silva, Sofia Orišková, Diogo Gonçalves, Ivo Paulo, José Condeço, Miguel Monteiro, Nuno M. Xavier, Amélia P. Rauter, João M. Bordado, Rui Galhano dos Santos

“…Eucalyptus globulus sawdust is a residue from the pulp and paper industry which has been underutilised and undervalued. The thermochemical liquefaction of…”
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Exploring Mannosylpurines as Copper Chelators and Cholinesterase Inhibitors with Potential for Alzheimer's Disease by Schino, Ignazio, Cantore, Mariangela, de Candia, Modesto, Altomare, Cosimo D, Maria, Catarina, Barros, João, Cachatra, Vasco, Calado, Patrícia, Shimizu, Karina, Freitas, Adilson A, Oliveira, Maria C, Ferreira, Maria J, Lopes, José N C, Colabufo, Nicola A, Rauter, Amélia P

“…Alzheimer's Disease (AD) is characterized by a progressive cholinergic neurotransmission imbalance, with a decrease of acetylcholinesterase (AChE) activity…”
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Unlocking the in vitro anti-inflammatory and antidiabetic potential of Polygonum maritimum by Rodrigues, Maria João, Custódio, Luísa, Lopes, Andreia, Oliveira, Marta, Neng, Nuno R., Nogueira, José M. F., Martins, Alice, Rauter, Amélia P., Varela, João, Barreira, Luísa

“…Context: Several Polygonum species (Polygonaceae) are used in traditional medicine in Asia, Europe and Africa to treat inflammation and diabetes. Objective:…”
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Extraction of volatile oil from aromatic plants with supercritical carbon dioxide: experiments and modeling by Coelho, Jose P, Cristino, Ana F, Matos, Patrícia G, Rauter, Amélia P, Nobre, Beatriz P, Mendes, Rui L, Barroso, João G, Mainar, Ana, Urieta, Jose S, Fareleira, João M N A, Sovová, Helena, Palavra, António F

“…An overview of the studies carried out in our laboratories on supercritical fluid extraction (SFE) of volatile oils from seven aromatic plants: pennyroyal…”
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Non-toxic Salvia sclareoides Brot. extracts as a source of functional food ingredients: Phenolic profile, antioxidant activity and prion binding properties by Rauter, Amélia P., Dias, Catarina, Martins, Alice, Branco, Isabel, Neng, Nuno R., Nogueira, José M., Goulart, Margarida, Silva, Filipa V.M., Justino, Jorge, Trevitt, Clare, Waltho, Jon P.

“…► Salvia sclareoides is the first Salvia species with prion binding properties. ► Total phenolic content, antioxidant activity and chemical profile are…”
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Antioxidants from aqueous decoction of carob pods biomass (Ceretonia siliqua L.): Optimisation using response surface methodology and phenolic profile by capillary electrophoresis by Roseiro, Luísa B., Tavares, Cláudia S., Roseiro, José C., Rauter, Amélia P.

“…► RSM was used for optimisation of aqueous decoction aiming antioxidants from carob biomass. ► Aqueous decoction provides added-value products from carob…”
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Design and synthesis of acetamido tri- and tetra-hydroxyazepanes: Potent and selective β- N-acetylhexosaminidase inhibitors by Li, Hongqing, Marcelo, Filipa, Bello, Claudia, Vogel, Pierre, Butters, Terry D., Rauter, Amélia P., Zhang, Yongmin, Sollogoub, Matthieu, Blériot, Yves

“…A series of seven-membered iminosugars bearing an acetamido group β- or γ- to the endocyclic nitrogen have been synthesized via simple transformations of…”
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Sugar-Based Enantiomeric and Conformationally Constrained Pyrrolo[2,1-c][1,4]-Benzodiazepines as Potential GABAA Ligands by Araújo, Ana C, Rauter, Amélia P, Nicotra, Francesco, Airoldi, Cristina, Costa, Barbara, Cipolla, Laura

“…Synthesis of a library of pyrrolo[2,1-c][1,4]-benzodiazepines derived from spiro bicyclic d- or l-proline analogues containing a d- or l-fructose moiety was…”
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Molecular Recognition of Rosmarinic Acid from Salviasclareoides Extracts by Acetylcholinesterase: A New Binding Site Detected by NMR Spectroscopy by Marcelo, Filipa, Dias, Catarina, Martins, Alice, Madeira, Paulo J, Jorge, Tiago, Florêncio, M. Helena, Cañada, F. Javier, Cabrita, Eurico J, Jiménez-Barbero, Jesús, Rauter, Amélia P

“…Acetylcholinesterase (AChE) inhibition is one of the most currently available therapies for the management of Alzheimer's disease (AD) symptoms. In this…”
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Synthesis of Tetrahydronaphthalene Lignan Esters by Intramolecular Cyclization of Ethyl p-Azidophenyl-2-phenylalkanoates and Evaluation of the Growth Inhibition of Human Tumor Cell Lines by Pinto, Orlando, Sardinha, João, Vaz, Pedro D, Piedade, Fátima, Calhorda, Maria J, Abramovitch, Rudolph, Nazareth, Nair, Pinto, Madalena, Nascimento, Maria S. J, Rauter, Amélia P

“…Intramolecular cyclization via nitrenium ion of 2-phenylpentanoic/2-phenylbutanoic acid esters with a terminal p-azidophenyl group gives direct access to…”
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Phenolic composition and antioxidant activity of Rocha pear and other pear cultivars – A comparative study by Salta, Joana, Martins, Alice, Santos, Rui G., Neng, Nuno R., Nogueira, José M.F., Justino, Jorge, Rauter, Amélia P.

“…The phenolic profile and the antioxidant activity of Rocha pear, a Portuguese pear cultivar, were determined and compared with the commercially available pear…”
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Can macroalgae provide promising anti-tumoral compounds? A closer look at Cystoseira tamariscifolia as a source for antioxidant and anti-hepatocarcinoma compounds by Vizetto-Duarte, Catarina, Custódio, Luísa, Acosta, Gerardo, Lago, João H G, Morais, Thiago R, Bruno de Sousa, Carolina, Gangadhar, Katkam N, Rodrigues, Maria João, Pereira, Hugo, Lima, Raquel T, Vasconcelos, M Helena, Barreira, Luísa, Rauter, Amélia P, Albericio, Fernando, Varela, João

“…Marine organisms are a prolific source of drug leads in a variety of therapeutic areas. In the last few years, biomedical, pharmaceutical and nutraceutical…”
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