Search Results - "Raute, Katrin"
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Dual-controlled optogenetic system for the rapid down-regulation of protein levels in mammalian cells
Published in Scientific reports (09-10-2018)“…Optogenetic switches are emerging molecular tools for studying cellular processes as they offer higher spatiotemporal and quantitative precision than…”
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Anti-CD3 Fab Fragments Enhance Tumor Killing by Human γδ T Cells Independent of Nck Recruitment to the γδ T Cell Antigen Receptor
Published in Frontiers in immunology (09-07-2018)“…T lymphocytes expressing the γδ T cell receptor (γδ TCR) can recognize antigens expressed by tumor cells and subsequently kill these cells. γδ T cells are…”
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Phytochrome‐Based Extracellular Matrix with Reversibly Tunable Mechanical Properties
Published in Advanced materials (Weinheim) (01-03-2019)“…Interrogation and control of cellular fate and function using optogenetics is providing revolutionary insights into biology. Optogenetic control of cells is…”
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Harnessing CD3 diversity to optimize CAR T cells
Published in Nature immunology (01-12-2023)“…Current US Food and Drug Administration-approved chimeric antigen receptor (CAR) T cells harbor the T cell receptor (TCR)-derived ζ chain as an intracellular…”
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Caveolin-1-dependent nanoscale organization of the BCR regulates B cell tolerance
Published in Nature immunology (01-10-2017)“…Immature B cells are subject to tolerance mechanisms that prevent the expression of self-reactive BCRs. Minguet and colleagues identify the membrane protein…”
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Breast Cancer Stem Cell-Derived Tumors Escape from γδ T-cell Immunosurveillance In Vivo by Modulating γδ T-cell Ligands
Published in Cancer immunology research (02-06-2023)“…There are no targeted therapies for patients with triple-negative breast cancer (TNBC). TNBC is enriched in breast cancer stem cells (BCSC), which play a key…”
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Caveolin-1-dependent BCR nanoscale organization regulates B cell tolerance
Published in Nature immunology (14-08-2017)“…Caveolin-1 (Cav1) regulates plasma membrane nano-organization and compartmentalization. Here, we demonstrate that Cav1 controlled the distribution of…”
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Biomaterials: Phytochrome‐Based Extracellular Matrix with Reversibly Tunable Mechanical Properties (Adv. Mater. 12/2019)
Published in Advanced materials (Weinheim) (01-03-2019)“…In article number 1806727, Wilfried Weber and co‐workers present a synthetic extracellular matrix, the mechanical properties of which can be tuned in a fast…”
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Kidins220 and Aiolos promote thymic iNKT cell development by reducing TCR signals
Published in Science advances (15-03-2024)“…Development of T cells is controlled by the signal strength of the TCR. The scaffold protein kinase D-interacting substrate of 220 kilodalton (Kidins220) binds…”
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Optogenetic light-tunable extracellular matrix
Published in Frontiers in bioengineering and biotechnology (2016)“…Abstract only…”
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