Search Results - "Rausch, P."
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Diverse cellular and organismal functions of the lysosomal thiol reductase GILT
Published in Molecular immunology (01-12-2015)“…•GILT catalyzes disulfide bond reduction in endocytic compartments.•GILT facilitates antigen presentation via MHC class I and II.•GILT regulates the cellular…”
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Efficacy of noncarbapenem therapy for the treatment of ceftriaxone-resistant Enterobacterales outside the urinary tract
Published in Antimicrobial stewardship & healthcare epidemiology : ASHE (2024)“…To determine the safety of noncarbapenem versus carbapenem antibiotics for treatment of adults with documented infection caused by ceftriaxone-resistant…”
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An exhaustion-like phenotype constrains the activity of CD4+ T cells specific for a self and melanoma antigen
Published in PloS one (15-04-2015)“…While the immune system has the capacity to recognize and destroy melanoma, tolerance mechanisms often hinder the development of effective anti-tumor immune…”
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Translation and content validity of the Dutch Impact of Vision Impairment questionnaire assessed by Three-Step Test-Interviewing
Published in Journal of patient-reported outcomes (05-01-2021)“…Background Patients suffering from exsudative retinal diseases may experience severe central vision loss and this might have impact on their daily activities…”
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THE PRESENT STATE OF ECUMENISM
Published in Perspectiva teológica (29-04-2017)“…The 500th Anniversary of the Reformation offers an occasion to reflect on the progress of the ecumenical movement, now over 100 years old. If a new atmosphere…”
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An Orally Active Small Molecule TGF-β Receptor I Antagonist Inhibits the Growth of Metastatic Murine Breast Cancer
Published in Anticancer research (01-06-2009)“…Transforming growth factor beta (TGF-beta) plays a complex role in breast carcinogenesis. Initially functioning as a tumor suppressor, this cytokine later…”
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GILT in Thymic Epithelial Cells Facilitates Central CD4 T Cell Tolerance to a Tissue-Restricted, Melanoma-Associated Self-Antigen
Published in The Journal of immunology (1950) (01-06-2020)“…Central tolerance prevents autoimmunity, but also limits T cell responses to potentially immunodominant tumor epitopes with limited expression in healthy…”
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A Stressful Microenvironment: Opposing Effects of the Endoplasmic Reticulum Stress Response in the Suppression and Enhancement of Adaptive Tumor Immunity
Published in International Reviews of Immunology (04-03-2015)“…The recent clinical success of immunotherapy in the treatment of certain types of cancer has demonstrated the powerful ability of the immune system to control…”
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Ultrasonographically guided thyroid biopsy: a review with emphasis on technique
Published in Journal of ultrasound in medicine (01-01-2001)“…We describe our technique for ultrasonographically guided fine‐needle aspiration biopsy of the thyroid that achieves a high rate of diagnostic specimens…”
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A randomized phase II trial using two different treatment schedules of gemcitabine and carboplatin in patients with advanced non-small-cell lung cancer
Published in Journal of thoracic oncology (01-01-2006)“…Gemcitabine and carboplatin combination therapy is an active and tolerable regimen in the treatment of non-small-cell lung cancer (NSCLC). Twenty-eight- and…”
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GILT Modulates CD4+ T-Cell Tolerance to the Melanocyte Differentiation Antigen Tyrosinase-Related Protein 1
Published in Journal of investigative dermatology (01-01-2012)“…Gamma-IFN-inducible lysosomal thiol reductase (GILT) facilitates major histocompatibility complex class II-restricted processing through endocytic reduction of…”
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GILT accelerates autoimmunity to the melanoma antigen tyrosinase-related protein 1
Published in The Journal of immunology (1950) (01-09-2010)“…Melanocyte differentiation Ags, including tyrosinase-related protein (TRP) 1, are relevant to both autoimmune skin depigmentation (vitiligo) and tumor…”
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From Vatican II to Pope Francis: Charting a Catholic Future ed. by Paul Crowley, S.J. (review)
Published in American Catholic studies (01-09-2015)Get full text
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Occasional Eucharistic Hospitality: Revisiting the Question
Published in Theological studies (Baltimore) (01-06-2013)“…The current Roman Catholic discipline regarding sacramental sharing does not seem to express the degree of communion that now exists between and among the…”
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Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota
Published in Nature genetics (01-11-2016)“…Andre Franke and colleagues perform a genome-wide association study for the gut microbiome, examining the influence of host genetics on overall microbial…”
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Nab2 maintains thymus cellularity with aging and stress
Published in Molecular immunology (01-05-2017)“…•Nab2KO mice have decreased thymus size, weight, and cellularity.•Nab2KO mice show accelerated decrease in thymic cellularity with age.•Nab2KO mice have…”
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Spontaneous resolution of an isolated ventricular septal defect in a dog
Published in Journal of the American Veterinary Medical Association (15-07-2003)“…A 5-month-old Maltese was examined because of a holosystolic heart murmur. Results of echocardiography were suggestive of a small isolated interventricular…”
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Colonic mucosa-associated microbiota is influenced by an interaction of Crohn disease and FUT2 (Secretor) genotype
Published in Proceedings of the National Academy of Sciences - PNAS (22-11-2011)“…The FUT2 (Secretor) gene is responsible for the presence of ABO histo-blood group antigens on the gastrointestinal mucosa and in bodily secretions. Individuals…”
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Further evidence for linkage of low-mid frequency hearing impairment to the candidate region on chromosome 4p16.3
Published in Clinical genetics (01-08-2001)“…We have investigated a three‐generation family with an autosomal dominant low–mid frequency hearing loss. Audiograms show consistently a hearing threshold of…”
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Catholics and Pentecostals: Troubled History, New Initiatives
Published in Theological studies (Baltimore) (01-12-2010)“…Catholics and Pentecostals in their various expressions—classical, charismatic, and Neo-Pentecostal—constitute about 75 percent of the total number of…”
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