Search Results - "Rausch, Christian"

NRPSpredictor2-a web server for predicting NRPS adenylation domain specificity by Röttig, Marc, Medema, Marnix H., Blin, Kai, Weber, Tilmann, Rausch, Christian, Kohlbacher, Oliver

“…The products of many bacterial non-ribosomal peptide synthetases (NRPS) are highly important secondary metabolites, including vancomycin and other antibiotics…”
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Dendroscope: An interactive viewer for large phylogenetic trees by Huson, Daniel H, Richter, Daniel C, Rausch, Christian, Dezulian, Tobias, Franz, Markus, Rupp, Regula

“…Research in evolution requires software for visualizing and editing phylogenetic trees, for increasingly very large datasets, such as arise in expression…”
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Phylogenetic analysis of condensation domains in NRPS sheds light on their functional evolution by Rausch, Christian, Hoof, Ilka, Weber, Tilmann, Wohlleben, Wolfgang, Huson, Daniel H

“…Non-ribosomal peptide synthetases (NRPSs) are large multimodular enzymes that synthesize a wide range of biologically active natural peptide compounds, of…”
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Consensus molecular subtype classification of colorectal adenomas by Komor, Malgorzata A, Bosch, Linda JW, Bounova, Gergana, Bolijn, Anne S, Delis‐van Diemen, Pien M, Rausch, Christian, Hoogstrate, Youri, Stubbs, Andrew P, de Jong, Mark, Jenster, Guido, van Grieken, Nicole CT, Carvalho, Beatriz, Wessels, Lodewyk FA, Jimenez, Connie R, Fijneman, Remond JA, Meijer, Gerrit A, Dits, Natasja, Bottcher, Rene, Hiemstra, Annemieke C, Ylstra, Bauke, Sie, Daoud, van den Broek, Evert, van der Meer, David, Pepers, Floor, Caldenhoven, Eric, Janssen, Bart, van Workum, Wilbert, van Lieshout, Stef, Bangma, Chris H., van Leenders, Geert, van de Werken, Harmen

“…Consensus molecular subtyping is an RNA expression‐based classification system for colorectal cancer (CRC). Genomic alterations accumulate during CRC…”
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Molecular characterization of colorectal adenomas reveals POFUT1 as a candidate driver of tumor progression by Komor, Malgorzata A., Wit, Meike, Berg, Jose, Martens de Kemp, Sanne R., Delis‐van Diemen, Pien M., Bolijn, Anne S., Tijssen, Marianne, Schelfhorst, Tim, Piersma, Sander R., Chiasserini, Davide, Sanders, Joyce, Rausch, Christian, Hoogstrate, Youri, Stubbs, Andrew P., Jong, Mark, Jenster, Guido, Carvalho, Beatriz, Meijer, Gerrit A., Jimenez, Connie R., Fijneman, Remond J.A.

“…Removal of colorectal adenomas is an effective strategy to reduce colorectal cancer (CRC) mortality rates. However, as only a minority of adenomas progress to…”
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Prevalence, trend and contributing factors of geriatric syndromes among older Swedes: results from the Stockholm County Council Public Health Surveys by Liang, Yajun, Rausch, Christian, Laflamme, Lucie, Möller, Jette

“…Evidence is scarce on the trend in prevalence of geriatric syndromes (GS). This study assesses how GS prevalence changes over time in Swedish older…”
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Geriatric Syndromes and Incident Chronic Health Conditions Among 9094 Older Community-Dwellers: Findings from the Lifelines Cohort Study by Rausch, Christian, van Zon, Sander K.R., Liang, Yajun, Laflamme, Lucie, Möller, Jette, de Rooij, Sophia E., Bültmann, Ute

“…To determine the association between geriatric syndromes and any specific incident chronic health conditions among older community-dwellers. Population-based…”
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Newly initiated cardiovascular medication and short-term risk of unintentional poisoning among Swedish middle-aged and older adults: A national register-based case-crossover study by Liang, Yajun, Zhao, Yang, Johnell, Kristina, Rausch, Christian, Laflamme, Lucie, Möller, Jette

“…Although some studies have shown the average side effects of cardiovascular medication, the short-term effect after newly initiated cardiovascular medications…”
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Microevolution of Cytochrome bd Oxidase in Staphylococci and Its Implication in Resistance to Respiratory Toxins Released by Pseudomonas by VOGGU, Lalitha, SCHLAG, Steffen, BISWAS, Raja, ROSENSTEIN, Ralf, RAUSCH, Christian, GÖTZ, Friedrich

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Combining structure and sequence information allows automated prediction of substrate specificities within enzyme families by Röttig, Marc, Rausch, Christian, Kohlbacher, Oliver

“…An important aspect of the functional annotation of enzymes is not only the type of reaction catalysed by an enzyme, but also the substrate specificity, which…”
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Genomic landscape of metastatic colorectal cancer by Haan, Josien C., Labots, Mariette, Rausch, Christian, Koopman, Miriam, Tol, Jolien, Mekenkamp, Leonie J. M., van de Wiel, Mark A., Israeli, Danielle, van Essen, Hendrik F., van Grieken, Nicole C. T., Voorham, Quirinus J. M., Bosch, Linda J. W., Qu, Xueping, Kabbarah, Omar, Verheul, Henk M. W., Nagtegaal, Iris D., Punt, Cornelis J. A., Ylstra, Bauke, Meijer, Gerrit A.

“…Response to drug therapy in individual colorectal cancer (CRC) patients is associated with tumour biology. Here we describe the genomic landscape of tumour…”
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Modeling early treatment response in AML from cell-free tumor DNA by Wang, Dantong, Rausch, Christian, Buerger, Simon A., Tschuri, Sebastian, Rothenberg-Thurley, Maja, Schulz, Melanie, Hasenauer, Jan, Ziemann, Frank, Metzeler, Klaus H., Marr, Carsten

“…Monitoring disease response after intensive chemotherapy for acute myeloid leukemia (AML) currently requires invasive bone marrow biopsies, imposing a…”
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The Association between Birthweight and Use of Cardiovascular Medications: The Role of Health Behaviors by Mo, Minjia, Thiesmeier, Robert, Kiwango, George, Rausch, Christian, Möller, Jette, Liang, Yajun

“…Background: There is limited evidence on the effect of low birthweight on the use of cardiovascular medications and the role of health behaviors. This study…”
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P434: MYELODYSPLASIA‐RELATED MUTATIONS IN THE NEW ELN CLASSIFICATION: DOES CLONAL SIZE PLAY A ROLE? by Rausch, Christian, Rothenberg‐Thurley, Maja, Dufour, Annika, Schneider, Stephanie, Gittinger, Hanna, Sauerland, Cristina, Görlich, Dennis, Krug, Utz, Berdel, Wolfgang E., Woermann, Bernhard J., Hiddemann, Wolfgang, Braess, Jan, Von Bergwelt‐Baildon, Michael, Spiekermann, Karsten, Herold, Tobias, Metzeler, Klaus H.

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P457: COMPLEX CARYOTYPE IS AN INDEPENDENT RISK FACTOR IN TP53‐MUTATED AML by Rausch, Christian, Rothenberg‐Thurley, Maja, Dufour, Annika, Schneider, Stephanie, Gittinger, Hanna, Sauerland, Cristina, Görlich, Dennis, Krug, Utz, Berdel, Wolfgang E., Woermann, Bernhard E., Hiddemann, Wolfgang, Braess, Jan, Von Bergwelt‐Baildon, Michael, Spiekermann, Karsten, Herold, Tobias, Metzeler, Klaus H.

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Monitoring the manufacturing and quality of medicines: a fundamental task of pharmacovigilance by Sardella, Marco, Belcher, Glyn, Lungu, Calin, Ignoni, Terenzio, Camisa, Manuela, Stenver, Doris Irene, Porcelli, Paolo, D’Antuono, Margherita, Castiglione, Nicola Gian, Adams, Anna, Furlan, Giovanni, Grisoni, Ilaria, Hall, Sarah, Boga, Laura, Mancini, Valentina, Ciuca, Mircea, Chonzi, David, Edwards, Brian, Mangoni, Arduino A, Tuccori, Marco, Prokofyeva, Elena, De Gregorio, Fabio, Bertazzoli Grabinski Broglio, Mario, van Leeuwen, Bert, Kruger, Paola, Rausch, Christian, Le Louet, Hervé

“…The collection and assessment of individual case safety reports (ICSRs) is important to detect unknown adverse drug reactions particularly in the first decade…”
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Karyotype evolution in response to chemoradiotherapy and upon recurrence of esophageal adenocarcinomas by van der Sluis, Karen, van Sandick, Johanna W., Koemans, Willem J., van den Bosch, Tom, Broeks, Annegien, Peters, Dennis, Seignette, Iris M., Rausch, Christian R., van Dijk, Erik, Snaebjornsson, Petur, van den Berg, José G., van Grieken, Nicole C.T., Ylstra, Bauke, Carvalho, Beatriz, Miedema, Daniël M., Kodach, Liudmila L.

“…The genome of esophageal adenocarcinoma (EAC) is highly unstable and might evolve over time. Here, we track karyotype evolution in EACs in response to…”
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GeneBreak: detection of recurrent DNA copy number aberration-associated chromosomal breakpoints within genes [version 2; peer review: 2 approved] by van den Broek, Evert, van Lieshout, Stef, Rausch, Christian, Ylstra, Bauke, van de Wiel, Mark A, Meijer, Gerrit A, Fijneman, Remond J.A, Abeln, Sanne

“…Development of cancer is driven by somatic alterations, including numerical and structural chromosomal aberrations. Currently, several computational methods…”
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Prescribing medications of questionable benefit prior to death: a retrospective study on older nursing home residents with and without dementia in Germany by Rausch, Christian, Hoffmann, Falk

“…Purpose We studied the prevalence of medications of questionable benefit in the last 6 months of life among older nursing home residents with and without…”
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Panitumumab can safely and effectively be substituted for cetuximab in the treatment of BRAF V600Emut metastatic colorectal cancer (mCRC) – A case series by Rausch, Christian, Schwicht, Charlotte, Doedens, Daphne, Forstpointner, Roswitha, Westphalen, Christoph Benedikt, Heinemann, Volker

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