Search Results - "Raum, Jeffrey C."

Epigenetic Priming of Enhancers Predicts Developmental Competence of hESC-Derived Endodermal Lineage Intermediates by Wang, Allen, Yue, Feng, Li, Yan, Xie, Ruiyu, Harper, Thomas, Patel, Nisha A., Muth, Kayla, Palmer, Jeffrey, Qiu, Yunjiang, Wang, Jinzhao, Lam, Dieter K., Raum, Jeffrey C., Stoffers, Doris A., Ren, Bing, Sander, Maike

“…Embryonic development relies on the capacity of progenitor cells to appropriately respond to inductive cues, a cellular property known as developmental…”
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Integration of Bmp and Wnt signaling by Hopx specifies commitment of cardiomyoblasts by Jain, Rajan, Li, Deqiang, Gupta, Mudit, Manderfield, Lauren J., Ifkovits, Jamie L., Wang, Qiaohong, Liu, Feiyan, Liu, Ying, Poleshko, Andrey, Padmanabhan, Arun, Raum, Jeffrey C., Li, Li, Morrisey, Edward E., Lu, Min Min, Won, Kyoung-Jae, Epstein, Jonathan A.

“…Making cardiomyocytes In the heart, multiple cell types work together. Cardiac progenitor cells give rise to cardiomyocyte, endothelial, or smooth muscle…”
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MafB is required for islet β cell maturation by Artner, Isabella, Blanchi, Bruno, Raum, Jeffrey C, Guo, Min, Kaneko, Tomomi, Cordes, Sabine, Sieweke, Michael, Stein, Roland

“…Pancreatic endocrine cell differentiation depends on transcription factors that also contribute in adult insulin and glucagon gene expression. Islet cell…”
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Insulin regulates carboxypeptidase E by modulating translation initiation scaffolding protein eIF4G1 in pancreatic β cells by Liew, Chong Wee, Assmann, Anke, Templin, Andrew T, Raum, Jeffrey C, Lipson, Kathryn L, Rajan, Sindhu, Qiang, Guifen, Hu, Jiang, Kawamori, Dan, Lindberg, Iris, Philipson, Louis H, Sonenberg, Nahum, Goldfine, Allison B, Stoffers, Doris A, Mirmira, Raghavendra G, Urano, Fumihiko, Kulkarni, Rohit N

“…Insulin resistance, hyperinsulinemia, and hyperproinsulinemia occur early in the pathogenesis of type 2 diabetes (T2D). Elevated levels of proinsulin and…”
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FoxA2, Nkx2.2, and PDX-1 Regulate Islet β-Cell-Specific mafA Expression through Conserved Sequences Located between Base Pairs −8118 and −7750 Upstream from the Transcription Start Site by Raum, Jeffrey C., Gerrish, Kevin, Artner, Isabella, Henderson, Eva, Guo, Min, Sussel, Lori, Schisler, Jonathan C., Newgard, Christopher B., Stein, Roland

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Islet β-Cell-Specific MafA Transcription Requires the 5′-Flanking Conserved Region 3 Control Domain by Raum, Jeffrey C., Hunter, Chad S., Artner, Isabella, Henderson, Eva, Guo, Min, Elghazi, Lynda, Sosa-Pineda, Beatriz, Ogihara, Takeshi, Mirmira, Raghavendra G., Sussel, Lori, Stein, Roland

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Diabetes Susceptibility Genes Pdx1 and Clec16a Function in a Pathway Regulating Mitophagy in β-Cells by Soleimanpour, Scott A, Ferrari, Alana M, Raum, Jeffrey C, Groff, David N, Yang, Juxiang, Kaufman, Brett A, Stoffers, Doris A

“…Mitophagy is a critical regulator of mitochondrial quality control and is necessary for elimination of dysfunctional mitochondria to maintain cellular…”
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A PDX1 cistrome and single-cell transcriptome resource of the developing pancreas by Yang, Xiaodun, Raum, Jeffrey C, Kim, Junil, Yu, Reynold, Yang, Juxiang, Rice, Gabriella, Li, Changhong, Won, Kyoung-Jae, Stanescu, Diana E, Stoffers, Doris A

“…Pancreatic and duodenal homeobox 1 (PDX1) is crucial for pancreas organogenesis, yet the dynamic changes in PDX1 binding in human or mouse developing pancreas…”
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Fibroblasts Derived From Human Adipose Stem Cells Produce More Effective Extracellular Matrix and Migrate Faster Compared to Primary Dermal Fibroblasts by Gersch, Robert P, Raum, Jeffrey C, Calvert, Catherine, Percec, Ivona

“…Abstract Background The efficacy of adipose-derived stem cells (ASCs) to improve wound healing has been extensively investigated. Unfortunately, no consistent…”
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FoxO1 protects against pancreatic β cell failure through NeuroD and MafA induction by Kitamura, Yukari Ido, Kitamura, Tadahiro, Kruse, Jan-Philipp, Raum, Jeffrey C., Stein, Roland, Gu, Wei, Accili, Domenico

“…Diabetes causes pancreatic β cell failure through hyperglycemia-induced oxidative stress, or “glucose toxicity.” We show that the forkhead protein FoxO1…”
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Calcineurin Signaling Regulates Human Islet β-Cell Survival by Soleimanpour, Scott A., Crutchlow, Michael F., Ferrari, Alana M., Raum, Jeffrey C., Groff, David N., Rankin, Matthew M., Liu, Chengyang, De León, Diva D., Naji, Ali, Kushner, Jake A., Stoffers, Doris A.

“…The calcium-regulated phosphatase calcineurin intersects with both calcium and cAMP-mediated signaling pathways in the pancreatic β-cell. Pharmacologic…”
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Tshz1 Regulates Pancreatic β-Cell Maturation by Raum, Jeffrey C, Soleimanpour, Scott A, Groff, David N, Coré, Nathalie, Fasano, Laurent, Garratt, Alistair N, Dai, Chunhua, Powers, Alvin C, Stoffers, Doris A

“…The homeodomain transcription factor Pdx1 controls pancreas organogenesis, specification of endocrine pancreas progenitors, and the postnatal growth and…”
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Hnf1α (MODY3) Regulates β-Cell-Enriched MafA Transcription Factor Expression by Hunter, Chad S, Maestro, Miguel Angel, Raum, Jeffrey C, Guo, Min, Thompson, Frederick H, Ferrer, Jorge, Stein, Roland

“…The MODY Hnf1α transcription factor activates endogenous MafA expression in pancreatic β-cells by binding within the Region 3 control domain. The expression…”
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Diabetes Susceptibility Genes Pdx1 and Clec16a Function in a Pathway Regulating Mitophagy in [Beta]-Cells by Soleimanpour, Scott A, Ferrari, Alana M, Raum, Jeffrey C, Groff, David N, Yang, Juxiang, Kaufman, Brett A, Stoffers, Doris A

“…Mitophagy is a critical regulator of mitochondrial quality control and is necessary for elimination of dysfunctional mitochondria to maintain cellular…”
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Tshz1 Regulates Pancreatic [Beta]-Cell Maturation by Raum, Jeffrey C, Soleimanpour, Scott A, Groff, David N, Coré, Nathalie, Fasano, Laurent, Garratt, Alistair N, Dai, Chunhua, Powers, Alvin C, Stoffers, Doris A

“…The homeodomain transcription factor Pdx1 controls pancreas organogenesis, specification of endocrine pancreas progenitors, and the postnatal growth and…”
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Insulin regulates carboxypeptidase E by modulating translation initiation scaffolding protein eIF4G1 in pancreatic [Beta] cells by Liew, Chong Wee, Assmann, Anke, Templin, Andrew T, Raum, Jeffrey C, Lipson, Kathryn L, Rajan, Sindhu, Qiang, Guifen, Hu, Jiang, Kawamori, Dan, Lindberg, Iris, Philipson, Louis H, Sonenberg, Nahum, Goldfine, Allison B, Stoffers, Doris A, Mirmira, Raghavendra G, Urano, Fumihiko, Kulkarni, Rohit N

“…Insulin resistance, hyperinsulinemia, and hyperproinsulinemia occur early in the pathogenesis of type 2 diabetes (T2D). Elevated levels of proinsulin and…”
Get full text

Insulin regulates carboxypeptidase E by modulating translation initiation scaffolding protein eIF4G1 in pancreatic β cells by Liew, Chong Wee, Assmann, Anke, Templin, Andrew T., Raum, Jeffrey C., Lipson, Kathryn L., Rajan, Sindhu, Qiang, Guifen, Hu, Jiang, Kawamori, Dan, Lindberg, Iris, Philipson, Louis H., Sonenberg, Nahum, Goldfine, Allison B., Stoffers, Doris A., Mirmira, Raghavendra G., Urano, Fumihiko, Kulkarni, Rohit N.

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MafB is required for islet [beta] cell maturation by Artner, Isabella, Blanchi, Bruno, Raum, Jeffrey C, Guo, Min

“…Pancreatic endocrine cell differentiation depends on transcription factors that also contribute in adult insulin and glucagon gene expression. Islet cell…”
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Islet b-Cell-Specific MafA Transcription Requires the 5'-Flanking Conserved Region 3 Control Domain by Raum, Jeffrey C, Hunter, Chad S, Artner, Isabella, Henderson, Eva, Guo, Min, Elghazi, Lynda, Sosa-Pineda, Beatriz, Ogihara, Takeshi, Mirmira, Raghavendra G, Sussel, Lori, Stein, Roland

“…MafA is a key transcriptional activator of islet b cells, and its exclusive expression within b cells of the developing and adult pancreas is distinct among…”
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Islet {beta}-cell-specific MafA transcription requires the 5'-flanking conserved Region 3 control domain by Raum, Jeffrey C, Hunter, Chad S, Artner, Isabella, Henderson, Eva, Guo, Min, Elghazi, Lynda, Sosa-Pineda, Beatriz, Ogihara, Takeshi, Mirmira, Raghavendra G, Sussel, Lori, Stein, Roland

“…MafA is a key transcriptional activator of islet beta cells and its exclusive expression within beta cells of the developing and adult pancreas is distinct…”
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