Search Results - "Raudenbush, Brian"

Bioluminescent method for assaying multiple semicarbazide-sensitive amine oxidase (SSAO) family members in both 96- and 384-well formats by Peet, Gregory W, Lukas, Susan, Hill-Drzewi, Melissa, Martin, Leslie, Rybina, Irina V, Roma, Teresa, Shoultz, Alycia, Zhu, Xiang, Cazacu, Daniela, Kronkaitis, Anthony, Baptiste, Alistair, Raudenbush, Brian C, August, E Michael, Modis, Louise Kelly

“…Vascular adhesion protein-1 (VAP-1), also known as semicarbazide-sensitive amine oxidase (SSAO) or copper-containing amine oxidase (AOC3, EC 1.4.3.6),…”
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Methodology for Regioselective Synthesis of Substituted Pyridines via Intramolecular Oximino Malonate Hetero Diels−Alder Reactions by Bland, Douglas C, Raudenbush, Brian C, Weinreb, Steven M

“…Various substituted pyridines can be prepared regioselectively by a sequence involving an intramolecular thermal or high-pressure Diels−Alder cycloaddition of…”
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Discovery and optimization of pyrazole amides as antagonists of CCR1 by Harcken, Christian, Sarko, Christopher, Mao, Can, Lord, John, Raudenbush, Brian, Razavi, Hossein, Liu, Pingrong, Swinamer, Alan, Disalvo, Darren, Lee, Thomas, Lin, Siqi, Kukulka, Alison, Grbic, Heather, Patel, Mita, Patel, Monica, Fletcher, Kim, Joseph, David, White, Della, Amodeo, Laura, Berg, Karen, Brown, Maryanne, Thomson, David S.

“…[Display omitted] •A HTS screen for CCR1 antagonists afforded a novel hit containing a pyrazole core.•Multi parameter optimization led to advanced candidate…”
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