Search Results - "Raucci, Angela"

The Janus face of HMGB1 in heart disease: a necessary update by Raucci, Angela, Di Maggio, Stefania, Scavello, Francesco, D’Ambrosio, Alessandro, Bianchi, Marco E., Capogrossi, Maurizio C.

“…High mobility group box 1 (HMGB1) is a ubiquitous nuclear protein involved in transcription regulation, DNA replication and repair and nucleosome assembly…”
Get full text

miR-34a: A Promising Target for Inflammaging and Age-Related Diseases by Raucci, Angela, Vinci, Maria Cristina

“…The term "inflammaging" describes the chronic, low-grade systemic inflammation that occurs during physiological aging in the absence of an overt infection…”
Get full text

Editorial: The role of circulating immune mediators in the crosstalk between cells of the immune system and cardiovascular system in CVDs by Anselmo, Achille, Bonalume, Veronica, Raucci, Angela

Get full text

High mobility group box 1 orchestrates tissue regeneration via CXCR4 by Tirone, Mario, Tran, Ngoc Lan, Ceriotti, Chiara, Gorzanelli, Andrea, Canepari, Monica, Bottinelli, Roberto, Raucci, Angela, Di Maggio, Stefania, Santiago, César, Mellado, Mario, Saclier, Marielle, François, Stéphanie, Careccia, Giorgia, He, Mingzhu, De Marchis, Francesco, Conti, Valentina, Ben Larbi, Sabrina, Cuvellier, Sylvain, Casalgrandi, Maura, Preti, Alessandro, Chazaud, Bénédicte, Al-Abed, Yousef, Messina, Graziella, Sitia, Giovanni, Brunelli, Silvia, Bianchi, Marco Emilio, Vénéreau, Emilie

“…Inflammation and tissue regeneration follow tissue damage, but little is known about how these processes are coordinated. High Mobility Group Box 1 (HMGB1) is…”
Get full text

soluble form of the receptor for advanced glycation endproducts (RAGE) is produced by proteolytic cleavage of the membrane-bound form by the sheddase a disintegrin and metalloprotease 10 (ADAM10) by Raucci, Angela, Cugusi, Simona, Antonelli, Antonella, Barabino, Silvia M, Monti, Lucilla, Bierhaus, Angelika, Reiss, Karina, Saftig, Paul, Bianchi, Marco E

“…The receptor for advanced glycation endproducts (RAGE) mediates responses to cell danger and stress. When bound by its many ligands (which include advanced…”
Get full text

The receptor for advanced glycation end-products (RAGE) is only present in mammals, and belongs to a family of cell adhesion molecules (CAMs) by Sessa, Luca, Gatti, Elena, Zeni, Filippo, Antonelli, Antonella, Catucci, Alessandro, Koch, Michael, Pompilio, Giulio, Fritz, Günter, Raucci, Angela, Bianchi, Marco E

“…The human receptor for advanced glycation endproducts (RAGE) is a multiligand cell surface protein belonging to the immunoglobulin superfamily, and is involved…”
Get full text

Epigenetic mechanisms in cardiovascular complications of diabetes: towards future therapies by Damiano, Giulia, Rinaldi, Raffaella, Raucci, Angela, Molinari, Chiara, Sforza, Annalisa, Pirola, Sergio, Paneni, Francesco, Genovese, Stefano, Pompilio, Giulio, Vinci, Maria Cristina

“…The pathophysiological mechanisms of cardiovascular disease and microvascular complications in diabetes have been extensively studied, but effective methods of…”
Get full text

Osteoblast proliferation or differentiation is regulated by relative strengths of opposing signaling pathways by Raucci, Angela, Bellosta, Paola, Grassi, Roberta, Basilico, Claudio, Mansukhani, Alka

“…Skeletal development requires the correct balance of osteoblast proliferation, survival, and differentiation which is modulated by a network of signaling…”
Get full text

Prothrombin is a binding partner of the human receptor of advanced glycation end products by Degani, Genny, Altomare, Alessandra, Digiovanni, Stefania, Arosio, Beatrice, Fritz, Guenter, Raucci, Angela, Aldini, Giancarlo, Popolo, Laura

“…The receptor for advanced glycation end products (RAGE) plays a key role in mammal physiology and in the etiology and progression of inflammatory and oxidative…”
Get full text

The microRNA-34a-Induced Senescence-Associated Secretory Phenotype (SASP) Favors Vascular Smooth Muscle Cells Calcification by Zuccolo, Estella, Badi, Ileana, Scavello, Francesco, Gambuzza, Irene, Mancinelli, Luigi, Macrì, Federica, Tedesco, Calogero C, Veglia, Fabrizio, Bonfigli, Anna Rita, Olivieri, Fabiola, Raucci, Angela

“…The senescence of vascular smooth muscle cells (VSMCs), characterized by the acquisition of senescence-associated secretory phenotype (SASP), is relevant for…”
Get full text

Persistent epigenetic signals propel a senescence-associated secretory phenotype and trained innate immunity in CD34 + hematopoietic stem cells from diabetic patients by Vinci, Maria Cristina, Costantino, Sarah, Damiano, Giulia, Rurali, Erica, Rinaldi, Raffaella, Vigorelli, Vera, Sforza, Annalisa, Carulli, Ermes, Pirola, Sergio, Mastroiacovo, Giorgio, Raucci, Angela, El-Osta, Assam, Paneni, Francesco, Pompilio, Giulio

“…Diabetes-induced trained immunity contributes to the development of atherosclerosis and its complications. This study aimed to investigate in humans whether…”
Get full text

Digital PCR for high sensitivity viral detection in false-negative SARS-CoV-2 patients by Poggio, Paolo, Songia, Paola, Vavassori, Chiara, Ricci, Veronica, Banfi, Cristina, Barbieri, Silvia Stella, Garoffolo, Gloria, Myasoedova, Veronika A., Piacentini, Luca, Raucci, Angela, Scopece, Alessandro, Sommariva, Elena, Vinci, Maria Cristina, Carcione, Davide, Biondi, Maria Luisa, Mancini, Maria Elisabetta, Formenti, Alberto, Andreini, Daniele, Assanelli, Emilio M., Agostoni, Piergiuseppe, Camera, Marina, Colombo, Gualtiero I., Pesce, Maurizio

“…Patients requiring diagnostic testing for coronavirus disease 2019 (COVID-19) are routinely assessed by reverse-transcription quantitative polymerase chain…”
Get full text

Effects of RAGE Deletion on the Cardiac Transcriptome during Aging by Scavello, Francesco, Piacentini, Luca, Castiglione, Stefania, Zeni, Filippo, Macrì, Federica, Casaburo, Manuel, Vinci, Maria Cristina, Colombo, Gualtiero I., Raucci, Angela

“…Cardiac aging is characterized by increased cardiomyocyte hypertrophy, myocardial stiffness, and fibrosis, which enhance cardiovascular risk. The receptor for…”
Get full text

Liraglutide preserves CD34 + stem cells from dysfunction Induced by high glucose exposure by Sforza, Annalisa, Vigorelli, Vera, Rurali, Erica, Perrucci, Gianluca Lorenzo, Gambini, Elisa, Arici, Martina, Metallo, Alessia, Rinaldi, Raffaella, Fiorina, Paolo, Barbuti, Andrea, Raucci, Angela, Sacco, Elena, Rocchetti, Marcella, Pompilio, Giulio, Genovese, Stefano, Vinci, Maria Cristina

“…Glucagon like peptide-1 receptor agonists (GLP-1RAs) have shown to reduce mortality and cardiovascular events in patients with type 2 diabetes mellitus (T2DM)…”
Get full text

Diabetes Induces a Transcriptional Signature in Bone Marrow-Derived CD34 + Hematopoietic Stem Cells Predictive of Their Progeny Dysfunction by D'Alessandra, Yuri, Chiesa, Mattia, Vigorelli, Vera, Ricci, Veronica, Rurali, Erica, Raucci, Angela, Colombo, Gualtiero Ivanoe, Pompilio, Giulio, Vinci, Maria Cristina

“…Hematopoietic stem/progenitor cells (HSPCs) participate in cardiovascular (CV) homeostasis and generate different types of blood cells including lymphoid and…”
Get full text

Doxorubicin and Trastuzumab Regimen Induces Biventricular Failure in Mice by Milano, Giuseppina, PhD, Raucci, Angela, PhD, Scopece, Alessandro, PhD, Daniele, Ranaldi, MSc, Guerrini, Uliano, PhD, Sironi, Luigi, PhD, Cardinale, Daniela, MD, Capogrossi, Maurizio C., MD, Pompilio, Giulio, MD, PhD

“…Background An increased risk for cardiac dysfunction is reported when the anti–epidermal growth factor receptor type 2 (ErbB2) antibody trastuzumab (Trz) is…”
Get full text

BPIFB4 and its longevity-associated haplotype protect from cardiac ischemia in humans and mice by Cattaneo, Monica, Aleksova, Aneta, Malovini, Alberto, Avolio, Elisa, Thomas, Anita, Alvino, Valeria Vincenza, Kilcooley, Michael, Pieronne-Deperrois, Marie, Ouvrard-Pascaud, Antoine, Maciag, Anna, Spinetti, Gaia, Kussauer, Sophie, Lemcke, Heiko, Skorska, Anna, Vasudevan, Praveen, Castiglione, Stefania, Raucci, Angela, David, Robert, Richard, Vincent, Beltrami, Antonio Paolo, Madeddu, Paolo, Puca, Annibale Alessandro

“…Long-living individuals (LLIs) escape age-related cardiovascular complications until the very last stage of life. Previous studies have shown that a…”
Get full text

Analytical Profile and Antioxidant and Anti-Inflammatory Activities of the Enriched Polyphenol Fractions Isolated from Bergamot Fruit and Leave by Baron, Giovanna, Altomare, Alessandra, Mol, Marco, Garcia, Jessica Leite, Correa, Camila, Raucci, Angela, Mancinelli, Luigi, Mazzotta, Sarah, Fumagalli, Laura, Trunfio, Giuseppe, Tucci, Luigi, Lombardo, Elena, Malara, Domenico, Janda, Elzbieta, Mollace, Vincenzo, Carini, Marina, Bombardelli, Ezio, Aldini, Giancarlo

“…The aim of the study is to compare the qualitative and semi-quantitative profile of the polyphenol fraction purified from the leaf (BLPF) and fruit (BFPF) of…”
Get full text

Circulating levels of AGEs and soluble RAGE isoforms are associated with all-cause mortality and development of cardiovascular complications in type 2 diabetes: a retrospective cohort study by Sabbatinelli, Jacopo, Castiglione, Stefania, Macrì, Federica, Giuliani, Angelica, Ramini, Deborah, Vinci, Maria Cristina, Tortato, Elena, Bonfigli, Anna Rita, Olivieri, Fabiola, Raucci, Angela

“…Advanced glycation end-products (AGEs) and their interaction with the receptor for advanced glycation end-products (RAGE) play a pivotal role in the…”
Get full text

High Phosphate-Induced JAK-STAT Signalling Sustains Vascular Smooth Muscle Cell Inflammation and Limits Calcification by Macrì, Federica, Vigorito, Ilaria, Castiglione, Stefania, Faggiano, Stefano, Casaburo, Manuel, Fanotti, Nadia, Piacentini, Luca, Vigetti, Davide, Vinci, Maria Cristina, Raucci, Angela

“…Vascular calcification (VC) is an age-related complication characterised by calcium-phosphate deposition in the arterial wall driven by the osteogenic…”
Get full text