Search Results - "Ratzinger, Franz"
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Digital PCR: A Sensitive and Precise Method for KIT D816V Quantification in Mastocytosis
Published in Clinical chemistry (Baltimore, Md.) (01-03-2018)“…The analytically sensitive detection of D816V in blood and bone marrow is important for diagnosing systemic mastocytosis (SM). Additionally, precise…”
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2
Lupus-anticoagulant testing at NOAC trough levels
Published in Thrombosis and haemostasis (01-08-2016)“…Non-vitamin K antagonist oral anticoagulants (NOAC), including rivaroxaban, apixaban or dabigatran, regularly show relevant effects on coagulation tests,…”
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3
Molecular quantification of tissue disease burden is a new biomarker and independent predictor of survival in mastocytosis
Published in Haematologica (Roma) (01-02-2020)“…A high allele burden of the D816V mutation in peripheral blood or bone marrow aspirates indicates multi-lineage hematopoietic involvement and has been…”
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4
Utility of sepsis biomarkers and the infection probability score to discriminate sepsis and systemic inflammatory response syndrome in standard care patients
Published in PloS one (11-12-2013)“…Physicians are regularly faced with severely ill patients at risk of developing infections. In literature, standard care wards are often neglected, although…”
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Performance Evaluation of the Fully Automated NeuMoDx RT-PCR Platform for the Quantification of CMV and EBV DNA in EDTA Plasma: Implications for Clinical Management and Establishment of a Conversion Formula
Published in Microbiology spectrum (21-12-2022)“…The NeuMoDx96 platform is a fully automated real-time PCR (RT-PCR) system. To provide continued testing quality with the introduction of new assays, the…”
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6
25(OH)D and 1,25(OH)D vitamin D fails to predict sepsis and mortality in a prospective cohort study
Published in Scientific reports (12-01-2017)“…The clinical role of vitamin D in sepsis and mortality prediction is controversially discussed. Therefore, we conducted a prospective cohort study on standard…”
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7
Different Types of Coagulase Are Associated With 28-Day Mortality in Patients With Staphylococcus aureus Bloodstream Infections
Published in Frontiers in cellular and infection microbiology (19-05-2020)“…, a leading cause of bacteremia and infective endocarditis, exploits the human coagulation system by using a wide range of specific virulence factors. However,…”
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8
Midday and nadir salivary cortisol appear superior to cortisol awakening response in burnout assessment and monitoring
Published in Scientific reports (14-06-2018)“…Burnout and work-related stress symptoms of anxiety disorder and depression cause prolonged work absenteeism and early retirement. Hence, reliable…”
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9
Low Vitamin D Levels Do Not Predict Hyperglycemia in Elderly Endurance Athletes (but in Controls)
Published in PloS one (01-06-2016)“…Recent studies revealed a link between hypovitaminosis D3 and the risk for hyperglycemia. Further mechanistic and interventional investigations suggested a…”
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10
A risk prediction model for screening bacteremic patients: a cross sectional study
Published in PloS one (03-09-2014)“…Bacteraemia is a frequent and severe condition with a high mortality rate. Despite profound knowledge about the pre-test probability of bacteraemia, blood…”
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11
Human diamine oxidase is readily released from activated neutrophils ex vivo and in vivo but is rarely elevated in bacteremic patients
Published in International journal of immunopathology and pharmacology (2020)“…During human diamine oxidase (DAO) ELISA development we noticed that in serum DAO concentrations appear to be higher when compared to plasma. Neutrophils…”
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12
A combination of routine blood analytes predicts fitness decrement in elderly endurance athletes
Published in PloS one (05-05-2017)“…Endurance sports are enjoying greater popularity, particularly among new target groups such as the elderly. Predictors of future physical capacities providing…”
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13
One-Year Follow-Up of COVID-19 Patients Indicates Substantial Assay-Dependent Differences in the Kinetics of SARS-CoV-2 Antibodies
Published in Microbiology spectrum (21-12-2022)“…Determination of antibody levels against the nucleocapsid (N) and spike (S) proteins of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are used…”
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14
Development of a fully automated high throughput PCR for the detection of SARS-CoV-2: The need for speed
Published in Virulence (01-12-2020)“…Currently, testing for coronavirus is performed with time and personnel consuming PCR assays. The aim of this study was to evaluate the sensitivity,…”
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15
Evaluation of the Septifast MGrade Test on Standard Care Wards--A Cohort Study
Published in PloS one (2016)“…The immediate need for appropriate antimicrobial therapy in septic patients requires the detection of the causative pathogen in a timely and reliable manner…”
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16
Biomarkers for differentiation of coronavirus disease 2019 or extracorporeal membrane oxygenation related inflammation and bacterial/fungal infections in critically ill patients: A prospective observational study
Published in Frontiers in medicine (06-10-2022)“…Secondary infections in coronavirus disease 2019 (COVID-19) patients are difficult to distinguish from inflammation associated with COVID-19 and/or…”
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17
A Multidisciplinary Intervention in Childhood Obesity Acutely Improves Insulin Resistance and Inflammatory Markers Independent From Body Composition
Published in Frontiers in pediatrics (21-02-2020)“…Childhood obesity is an increasing health care problem associated with insulin resistance and low-level systemic inflammation, which can ultimately lead to…”
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18
Rapid diagnostic algorithms as a screening tool for tuberculosis: an assessor blinded cross-sectional study
Published in PloS one (21-11-2012)“…A major obstacle to effectively treat and control tuberculosis is the absence of an accurate, rapid, and low-cost diagnostic tool. A new approach for the…”
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19
Hereditary α tryptasemia is a valid genetic biomarker for severe mediator-related symptoms in mastocytosis
Published in Blood (14-01-2021)“…Mastocytosis is a hematopoietic neoplasm characterized by expansion of KIT D816V-mutated clonal mast cells in various organs and severe or even…”
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20
Machine learning for fast identification of bacteraemia in SIRS patients treated on standard care wards: a cohort study
Published in Scientific reports (15-08-2018)“…Bacteraemia is a life-threating condition requiring immediate diagnostic and therapeutic actions. Blood culture (BC) analyses often result in a low true…”
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