Search Results - "Rattanapisit, Kaewta"
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Monoclonal Antibodies B38 and H4 Produced in Nicotiana benthamiana Neutralize SARS-CoV-2 in vitro
Published in Frontiers in plant science (27-11-2020)“…The ongoing coronavirus disease 2019 (COVID-19) outbreak caused by novel zoonotic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was initially…”
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Quality control in SARS-CoV-2 RBD-Fc vaccine production using LC–MS to confirm strain selection and detect contaminations from other strains
Published in Scientific reports (26-04-2024)“…Coronavirus disease of 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is an ongoing outbreak, disrupting human life…”
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Rapid production of SARS-CoV-2 receptor binding domain (RBD) and spike specific monoclonal antibody CR3022 in Nicotiana benthamiana
Published in Scientific reports (19-10-2020)“…Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for the ongoing global outbreak of coronavirus disease (COVID-19) which is a…”
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In vitro and in vivo studies of plant-produced Atezolizumab as a potential immunotherapeutic antibody
Published in Scientific reports (29-08-2023)“…Immune checkpoint inhibitors are a well-known class of immunotherapeutic drugs that have been used for effective treatment of several cancers. Atezolizumab…”
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Plant-produced SARS-CoV-2 receptor binding domain (RBD) variants showed differential binding efficiency with anti-spike specific monoclonal antibodies
Published in PloS one (11-08-2021)“…Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for the ongoing coronavirus disease (COVID-19) pandemic which is characterized by…”
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Plant-Produced Receptor-Binding Domain of SARS-CoV-2 Elicits Potent Neutralizing Responses in Mice and Non-human Primates
Published in Frontiers in plant science (13-05-2021)“…The emergence of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected global public health…”
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Effect of plant produced Anti-hIL-6 receptor antibody blockade on pSTAT3 expression in human peripheral blood mononuclear cells
Published in Scientific reports (24-07-2023)“…As a response to invasion by pathogens, the secretion of interleukin 6 (IL-6) which is a cytokine, activates IL-6/JAKs/STAT3 intracellular signaling via.,…”
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Neutralizing activity of anti-respiratory syncytial virus monoclonal antibody produced in Nicotiana benthamiana
Published in Human vaccines & immunotherapeutics (31-12-2024)“…Respiratory syncytial virus (RSV) is a highly contagious virus that affects the lungs and respiratory passages of many vulnerable people. It is a leading cause…”
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Feasibility of plant-expression system for production of recombinant anti-human IgE: An alternative production platform for therapeutic monoclonal antibodies
Published in Frontiers in plant science (02-12-2022)“…Omalizumab, the anti-immunoglobulin IgE antibody is the only approved and available monoclonal antibody as an auxiliary medicament for the severe respiratory…”
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Development of Plant-Produced Recombinant ACE2-Fc Fusion Protein as a Potential Therapeutic Agent Against SARS-CoV-2
Published in Frontiers in plant science (07-01-2021)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease (COVID-19) which has recently emerged as a potential…”
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Development of SARS-CoV-2 neutralizing antibody detection assay by using recombinant plant-produced proteins
Published in Biotechnology reports (Amsterdam, Netherlands) (01-06-2023)“…•Plants could offer a cost-effective platform for producing diagnostic reagents.•Recombinant ACE2 was produced in Nicotiana benthamiana by transient…”
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Production of monoclonal antibodies against botulinum neurotoxin in Nicotiana benthamiana
Published in Human vaccines & immunotherapeutics (31-12-2024)“…Botulism is a fatal neurologic disease caused by the botulinum toxin (BoNT) produced by . It is a rare but highly toxic disease with symptoms, such as cramps,…”
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Functional Characterization of Pembrolizumab Produced in Nicotiana benthamiana Using a Rapid Transient Expression System
Published in Frontiers in plant science (09-09-2021)“…The striking innovation and clinical success of immune checkpoint inhibitors (ICIs) have undoubtedly contributed to a breakthrough in cancer immunotherapy…”
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Antitumor effect of plant-produced anti-CTLA-4 monoclonal antibody in a murine model of colon cancer
Published in Frontiers in plant science (29-08-2023)“…Cytotoxic T lymphocyte-associated protein 4 (CTLA-4) is an immune checkpoint regulator exclusively expressed on T cells that obstructs the cell’s effector…”
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Lysine 206 in Arabidopsis phytochrome A is the major site for ubiquitin-dependent protein degradation
Published in Journal of biochemistry (Tokyo) (01-02-2016)“…Phytochrome A (phyA) is a light labile phytochrome that mediates plant development under red/far-red light condition. Degradation of phyA is initiated by red…”
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Plant-made antibody against miroestrol: a new platform for expression of full-length immunoglobulin G against small-molecule targets in immunoassays
Published in Plant cell reports (01-04-2021)“…Key message Plant expression platform is the new source of immunoglobulin G (IgG) toward small low-molecular-weight targets. The plant-made monoclonal…”
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A recombinant subunit vaccine candidate produced in plants elicits neutralizing antibodies against SARS-CoV-2 variants in macaques
Published in Frontiers in plant science (28-09-2022)“…Since the outbreak of the coronavirus disease (COVID) pandemic in 2019, the development of effective vaccines to combat the infection has been accelerated…”
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Recombinant human osteopontin expressed in Nicotiana benthamiana stimulates osteogenesis related genes in human periodontal ligament cells
Published in Scientific reports (11-12-2017)“…Tissue engineering aims to utilise biologic mediators to facilitate tissue regeneration. Several recombinant proteins have potential to mediate induction of…”
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Expression optimization, purification and in vitro characterization of human epidermal growth factor produced in Nicotiana benthamiana
Published in Biotechnology reports (Amsterdam, Netherlands) (01-12-2020)“…•Growth factors play a crucial role in tissue repair and wound healing.•Recombinant human epidermal growth factor was produced in N. benthamiana by…”
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