Search Results - "Rattan, Ajitanuj"
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Synergy between the classical and alternative pathways of complement is essential for conferring effective protection against the pandemic influenza A(H1N1) 2009 virus infection
Published in PLoS pathogens (01-03-2017)“…The pandemic influenza A(H1N1) 2009 virus caused significant morbidity and mortality worldwide thus necessitating the need to understand the host factors that…”
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Diverse Epitope Specificity, Immunodominance Hierarchy, and Functional Avidity of Effector CD4 T Cells Established During Priming Is Maintained in Lung After Influenza A Virus Infection
Published in Frontiers in immunology (06-04-2018)“…One of the major contributions to protective immunity to influenza viruses that is provided by virus-specific CD4 T cells is delivery of effector function to…”
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Development of a Mouse Model to Explore CD4 T Cell Specificity, Phenotype, and Recruitment to the Lung after Influenza B Infection
Published in Pathogens (Basel) (15-02-2022)“…The adaptive T cell response to influenza B virus is understudied, relative to influenza A virus, for which there has been considerable attention and progress…”
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Complement receptor 2 as a novel therapeutic target to suppress germinal center-derived autoantibody production in a SLE mouse model
Published in The Journal of immunology (1950) (01-05-2024)“…Abstract Presence of spontaneous germinal center (GCs) in SLE patients correlates with the production of pathogenic, isotype-switched antibodies (Abs) and…”
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CD4 T cells in protection from influenza virus: Viral antigen specificity and functional potential
Published in Immunological reviews (01-07-2018)“…Summary CD4 T cells convey a number of discrete functions to protective immunity to influenza, a complexity that distinguishes this arm of adaptive immunity…”
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CD4 T Cell Epitope Specificity and Cytokine Potential Are Preserved as Cells Transition from the Lung Vasculature to Lung Tissue following Influenza Virus Infection
Published in Journal of virology (01-07-2018)“…Pulmonary CD4 T cells are critical in respiratory virus control, both by delivering direct effector function and through coordinating responses of other immune…”
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Protein Vaccination Directs the CD4 + T Cell Response toward Shared Protective Epitopes That Can Be Recalled after Influenza Virus Infection
Published in Journal of virology (15-10-2019)“…Vaccination is widely used to generate protective immunity against influenza virus. CD4 T cells contribute in diverse ways to protective immunity, most…”
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A Novel Vaccine Strategy to Overcome Poor Immunogenicity of Avian Influenza Vaccines through Mobilization of Memory CD4 T Cells Established by Seasonal Influenza
Published in The Journal of immunology (1950) (15-09-2019)“…Avian influenza vaccines exhibit poor immunogenicity in humans. We hypothesized that one factor underlying weak B cell responses was sequence divergence…”
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CD 4 T cells in protection from influenza virus: Viral antigen specificity and functional potential
Published in Immunological reviews (01-07-2018)“…Summary CD 4 T cells convey a number of discrete functions to protective immunity to influenza, a complexity that distinguishes this arm of adaptive immunity…”
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