Search Results - "Ratnoff, O D"

Gene Transfer in vivo: Sustained Expression and Regulation of Genes Introduced into the Liver by Receptor-Targeted Uptake by Perales, Jose Carlos, Ferkol, Thomas, Beegen, Helga, Ratnoff, Oscar D., Hanson, Richard W.

“…Receptor-mediated gene transfer has been used to introduce genes into tissues of animals in vivo. The genes introduced by this approach have been transiently…”
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Induction of Expression of Monocyte Interleukin 1 by Hageman Factor (Factor XII) by Toossi, Zahra, Sedor, John R., Mettler, Mark A., Everson, Barbara, Young, Tsuguang, Ratnoff, Oscar D.

“…The results reported here indicate that activated species of Hageman factor (HF, factor XII), a protein that mediates blood clotting, fibrinolysis, and…”
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Factor XI (Plasma Thromboplastin Antecedent) Deficiency in Ashkenazi Jews is a Bleeding Disorder that Can Result from Three Types of Point Mutations by Asakai, Rei, Chung, Dominic W., Ratnoff, Oscar D., Davie, Earl W.

“…Factor XI (plasma thromboplastin antecedent) deficiency is a blood coagulation abnormality occurring in high frequency in Ashkenazi Jews. Three independent…”
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Familial Sneddon's syndrome : clinical, hematologic, and radiographic findings in two brothers by PETTEE, A. D, WASSERMAN, B. A, ADAMS, N. L, MCMULLEN, W, SMITH, H. R, WOODS, S. L, RATNOFF, O. D

“…We present the clinical, hematologic, and radiographic findings in two brothers with Sneddon's syndrome (stroke and livedo reticularis) and antiphospholipid…”
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The changing prognosis of classic hemophilia (factor VIII "deficiency") by Jones, P K, Ratnoff, O D

“…To estimate relative risk of mortality and median life expectancy for patients with classic hemophilia by a life-table analysis, taking into account deaths…”
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Mitogenic Effects of Coagulation Factor XII and Factor XIIa on HepG2 Cells by Schmeidler-Sapiro, Katherine T., Ratnoff, Oscar D., Gordon, Erlinda M.

“…The structure of coagulation factor XII (Hageman factor), inferred from its DNA sequence, includes two epidermal growth factor (EGF)-homologous domains in its…”
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Regulation of the phosphoenolpyruvate carboxykinase/human factor IX gene introduced into the livers of adult rats by receptor-mediated gene transfer by Ferkol, T, Lindberg, G L, Chen, J, Perales, J C, Crawford, D R, Ratnoff, O D, Hanson, R W

“…Gene transfer systems targeting the asialoglycoprotein receptor have been developed to introduce functional genes into cells in culture and livers of intact…”
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Primary pulmonary hypertension in patients with classic hemophilia by Goldsmith, Jr, G H, Baily, R G, Brettler, D B, Davidson, Jr, W R, Ballard, J O, Driscol, T E, Greenberg, J M, Kasper, C K, Levine, P H, Ratnoff, O D

“…Five patients with classic hemophilia were found to have primary pulmonary hypertension, a disorder not previously recognized in this population. All patients…”
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Airway obstruction in hemophilia (factor VIII deficiency): a 28-year institutional review by Bogdan, C J, Strauss, M, Ratnoff, O D

“…Life-threatening airway compromise is rarely reported as a major complication of coagulation disorders. However, before adequate factor-replacement therapy…”
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Inhibition of the Activation of Hageman Factor (Factor XII) by Human Vascular Endothelial Cell Culture Supernates by Ratnoff, Oscar D., Everson, Barbara, Embury, Paula, Ziats, Nicholas P., Anderson, James M., Emanuelson, Marlene M., Malemud, Charles J.

“…The supernatant fluid (conditioned medium) of cultured human vascular endothelial cells inhibits activation of Hageman factor (factor XII), whether by ellagic…”
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Acquisition of antibody to lymphadenopathy-associated virus in patients with classic hemophilia (factor VIII deficiency) by Lederman, M M, Ratnoff, O D, Evatt, B L, McDougal, J S

“…Antibody to lymphadenopathy-associated virus (LAV) was assayed in 461 serum and plasma samples that had been obtained from 149 patients with classic hemophilia…”
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Inhibition of the activation of Hageman factor (factor XII) by peripheral blood cells by RATNOFF, O. D, EMANUELSON, M. M, ZIATS, N. P

“…Suspensions of peripheral blood mononuclear cells (PBMC), monocytes, T or B lymphocytes, platelets or granulocytes, and cell-depleted supernatant fluids of…”
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The Influence of Estrogen and Prolactin on Hageman Factor (Factor XII) Titer in Ovariectomized and Hypophysectomized Rats by Gordon, Erlinda M., Douglas, Janice G., Ratnoff, Oscar D., Arafah, Baha'Uddin M.

“…The synthesis of prothrombin in hepatic microsomes is augmented in intact estrogen-treated rats and in hypophysectomized rats treated with purified prolactin…”
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Amidolytic Properties of Single-Chain Activated Hageman Factor by Ratnoff, Oscar D., Saito, Hidehiko

“…Activation of Hageman factor (Factor XII) upon exposure to negatively charged agents has been attributed to proteolytic cleavage of this molecule. To examine…”
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The psychogenic purpuras: a review of autoerythrocyte sensitization, autosensitization to DNA, "hysterical" and factitial bleeding, and the religious stigmata by Ratnoff, O D

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Inhibition of the activation of Hageman factor (factor XII) by complement subcomponent C1q by REHMUS, E. H, GREENE, B. M, EVERSON, B. A, RATNOFF, O. D

“…Hageman factor (HF, Factor XII) is activated by glass, collagen, and ellagic acid, and initiates blood coagulation via the intrinsic pathway. C1q inhibits…”
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Purification of Hageman Factor (Factor XII) on Columns of Popcorn-Agarose by Ratnoff, Oscar D., Everson, Barbara, Donaldson, Virginia H., Mitchell, Bridget H.

“…Purification of Hageman factor (HF, factor XII) from human plasma is a tedious procedure and the product is not always in the precursor form. Hojima has…”
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Thrombosis and the hypercoagulable state by Ratnoff, O D

“…Our understanding of thrombosis remains anchored to Virchow's view that the evolution of a thrombus is fostered by vascular damage, by retarded blood flow, and…”
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Interactions among Hageman Factor, Plasma Prekallikrein, High Molecular Weight Kininogen, and Plasma Thromboplastin Antecedent by Ratnoff, Oscar D., Saito, Hidehiko

“…To investigate the earliest steps of the intrinsic clotting pathway, Hageman factor (Factor XII) was exposed to Sephadex gels to which ellagic acid had been…”
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Inhibition of the activation of hageman factor (factor XII) by eosinophils and eosinophilic constituents by Ratnoff, O D, Gleich, G J, Shurin, S B, Kazura, J, Everson, B, Embury, P

“…Several syndromes characterized by striking eosinophilia may be complicated by thrombosis. The experiments described indicate that, paradoxically, eosinophils…”
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