Search Results - "Ratnacaram, Chandrahas Koumar"

Cyclin-dependent kinase 1 (Cdk1) is essential for cell division and suppression of DNA re-replication but not for liver regeneration by Diril, M. Kasim, Ratnacaram, Chandrahas Koumar, Padmakumar, V. C, Du, Tiehua, Wasser, Martin, Coppola, Vincenzo, Tessarollo, Lino, Kaldis, Philipp

“…Cyclin-dependent kinase 1 (Cdk1) is an archetypical kinase and a central regulator that drives cells through G2 phase and mitosis. Knockouts of Cdk2, Cdk3,…”
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Repertoires of MicroRNA-30 family as gate-keepers in lung cancer by Kanthaje, Shruthi, Baikunje, Nandakishore, Kandal, Irfan, Ratnacaram, Chandrahas Koumar

“…Lung cancer is a prominent global health issue responsible for the highest fraction of cancer-related mortality. The disease burden has incited the…”
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Established and novel Cdk/cyclin complexes regulating the cell cycle and development by Gopinathan, Lakshmi, Ratnacaram, Chandrahas Koumar, Kaldis, Philipp

“…The identification of new members in the Cdk and cyclin families, functions for many of which are still emerging, has added new facets to the cell cycle…”
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Temporally controlled ablation of PTEN in adult mouse prostate epithelium generates a model of invasive prostatic adenocarcinoma by Ratnacaram, Chandrahas Koumar, Teletin, Marius, Jiang, Ming, Meng, Xiangjun, Chambon, Pierre, Metzger, Daniel

“…Studies of prostate cancer pathogenesis and development of new therapies have been hampered by a lack of appropriate mouse models. We have generated…”
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Emerging cell cycle related non-coding RNA biomarkers from saliva and blood for oral squamous cell carcinoma by Kalmatte, Asrarunissa, Rekha, Punchappady Devasya, Ratnacaram, Chandrahas Koumar

“…The unnotified or undifferentiable early stages of oral squamous cell carcinoma (OSCC) progression are the prime reasons for late-stage detection and poor…”
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Combinatorial approaches of nanotherapeutics for inflammatory pathway targeted therapy of prostate cancer by Johnson, Renjith P., Ratnacaram, Chandrahas Koumar, Kumar, Lalit, Jose, Jobin

“…Prostate cancer (PC) is the most prevalent male urogenital cancer worldwide. PC patients presenting an advanced or metastatic cancer succumb to the disease,…”
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Circulating metabolite biomarkers: a game changer in the human prostate cancer diagnosis by Krishnan, Sabareeswaran, Kanthaje, Shruthi, Punchappady, Devasya Rekha, Mujeeburahiman, M., Ratnacaram, Chandrahas Koumar

“…Purpose Prostate cancer (PCa) is the second most commonly diagnosed cancer in men in Western and Asian countries. Serum prostate-specific antigen (PSA) test…”
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Antisense oligonucleotide-mediated MDM4 exon 6 skipping impairs tumor growth by Dewaele, Michael, Tabaglio, Tommaso, Willekens, Karen, Bezzi, Marco, Teo, Shun Xie, Low, Diana H P, Koh, Cheryl M, Rambow, Florian, Fiers, Mark, Rogiers, Aljosja, Radaelli, Enrico, Al-Haddawi, Muthafar, Tan, Soo Yong, Hermans, Els, Amant, Frederic, Yan, Hualong, Lakshmanan, Manikandan, Koumar, Ratnacaram Chandrahas, Lim, Soon Thye, Derheimer, Frederick A, Campbell, Robert M, Bonday, Zahid, Tergaonkar, Vinay, Shackleton, Mark, Blattner, Christine, Marine, Jean-Christophe, Guccione, Ernesto

“…MDM4 is a promising target for cancer therapy, as it is undetectable in most normal adult tissues but often upregulated in cancer cells to dampen p53…”
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CDK2 regulates the NRF1/ Ehmt1 axis during meiotic prophase I by Palmer, Nathan, Talib, S Zakiah A, Ratnacaram, Chandrahas Koumar, Low, Diana, Bisteau, Xavier, Lee, Joanna Hui Si, Pfeiffenberger, Elisabeth, Wollmann, Heike, Tan, Joel Heng Loong, Wee, Sheena, Sobota, Radoslaw, Gunaratne, Jayantha, Messerschmidt, Daniel M, Guccione, Ernesto, Kaldis, Philipp

“…Meiosis generates four genetically distinct haploid gametes over the course of two reductional cell divisions. Meiotic divisions are characterized by the…”
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Cdk2 catalytic activity is essential for meiotic cell division in vivo by Chauhan, Sangeeta, Diril, M Kasim, Lee, Joanna H S, Bisteau, Xavier, Manoharan, Vanessa, Adhikari, Deepak, Ratnacaram, Chandrahas Koumar, Janela, Baptiste, Noffke, Juliane, Ginhoux, Florent, Coppola, Vincenzo, Liu, Kui, Tessarollo, Lino, Kaldis, Philipp

“…Cyclin-dependent kinases (Cdks) control the eukaryotic cell cycle by phosphorylating serine and threonine residues in key regulatory proteins, but some Cdk…”
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