Search Results - "Ratliff, Scott"

Chronic Health Conditions as a Risk Factor for Falls among the Community-Dwelling US Older Adults: A Zero-Inflated Regression Modeling Approach by Paliwal, Yoshita, Ratliff, Scott M., Slattum, Patricia W.

“…Falls are an important health concern among older adults due to age-related changes in the body. Having a medical history of chronic health condition may pose…”
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The Socioeconomic Gradient in Epigenetic Ageing Clocks: Evidence from the Multi-Ethnic Study of Atherosclerosis and the Health and Retirement Study by Schmitz, Lauren L., Zhao, Wei, Ratliff, Scott M., Goodwin, Julia, Miao, Jiacheng, Lu, Qiongshi, Guo, Xiuqing, Taylor, Kent D., Ding, Jingzhong, Liu, Yongmei, Levine, Morgan, Smith, Jennifer A.

“…Epigenetic clocks have been widely used to predict disease risk in multiple tissues or cells. Their success as a measure of biological ageing has prompted…”
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Neighborhood characteristics influence DNA methylation of genes involved in stress response and inflammation: The Multi-Ethnic Study of Atherosclerosis by Smith, Jennifer A., Zhao, Wei, Wang, Xu, Ratliff, Scott M., Mukherjee, Bhramar, Kardia, Sharon L. R., Liu, Yongmei, Roux, Ava V. Diez, Needham, Belinda L.

“…Living in a disadvantaged neighborhood is associated with poor health outcomes even after accounting for individual-level socioeconomic factors. The chronic…”
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Associations of Early-Life Adversity With Later-Life Epigenetic Aging Profiles in the Multi-Ethnic Study of Atherosclerosis by Schmitz, Lauren L, Duffie, Elizabeth, Zhao, Wei, Ratliff, Scott M, Ding, Jingzhong, Liu, Yongmei, Merkin, Sharon Stein, Smith, Jennifer A, Seeman, Teresa

“…Abstract Epigenetic biomarkers of accelerated aging have been widely used to predict disease risk and may enhance our understanding of biological mechanisms…”
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DNA Methylation at C-Reactive Protein-Associated CpG Sites May Mediate the Pathway Between Educational Attainment and Cognition by Stoldt, Meike, Ammous, Farah, Lin, Lisha, Ratliff, Scott M, Ware, Erin B, Faul, Jessica D, Zhao, Wei, Kardia, Sharon L R, Smith, Jennifer A

“…Abstract Growing evidence has linked inflammatory processes to cognitive decline and dementia. This work examines whether an epigenetic marker of C-reactive…”
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Epigenome-wide association study of long-term psychosocial stress in older adults by Opsasnick, Lauren A, Zhao, Wei, Schmitz, Lauren L, Ratliff, Scott M, Faul, Jessica D, Zhou, Xiang, Needham, Belinda L, Smith, Jennifer A

“…Long-term psychosocial stress is strongly associated with negative physical and mental health outcomes, as well as adverse health behaviours; however, little…”
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Depressive symptoms, psychiatric medication use, and risk of type 2 diabetes: results from the Health and Retirement Study by Ratliff, Scott, M.S, Mezuk, Briana, Ph.D

“…Abstract Objective This prospective study investigates the relationships between depressive symptoms, psychiatric medication use, and their interaction on risk…”
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Patients' adoption of and feature access within electronic patient portals by Elston Lafata, Jennifer, Miller, Carrie A, Shires, Deirdre A, Dyer, Karen, Ratliff, Scott M, Schreiber, Michelle

“…We describe online portal account adoption and feature access among subgroups of patients who traditionally have been disadvantaged or represent those with…”
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Intrinsic and extrinsic epigenetic age acceleration are associated with hypertensive target organ damage in older African Americans by Smith, Jennifer A, Raisky, Jeremy, Ratliff, Scott M, Liu, Jiaxuan, Kardia, Sharon L R, Turner, Stephen T, Mosley, Thomas H, Zhao, Wei

“…Epigenetic age acceleration, a measure of biological aging based on DNA methylation, is associated with cardiovascular mortality. However, little is known…”
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Epigenetic age acceleration is associated with cardiometabolic risk factors and clinical cardiovascular disease risk scores in African Americans by Ammous, Farah, Zhao, Wei, Ratliff, Scott M, Mosley, Thomas H, Bielak, Lawrence F, Zhou, Xiang, Peyser, Patricia A, Kardia, Sharon L R, Smith, Jennifer A

“…Cardiovascular disease (CVD) is the leading cause of mortality among US adults. African Americans have higher burden of CVD morbidity and mortality compared to…”
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Epigenetic age acceleration is associated with blood lipid levels in a multi-ancestry sample of older U.S. adults by Lin, Lisha, Kiryakos, Jenna, Ammous, Farah, Ratliff, Scott M, Ware, Erin B, Faul, Jessica D, Kardia, Sharon L R, Zhao, Wei, Birditt, Kira S, Smith, Jennifer A

“…Dyslipidemia, which is characterized by an unfavorable lipid profile, is a key risk factor for cardiovascular disease (CVD). Understanding the relationships…”
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Epigenome-wide association study identifies DNA methylation sites associated with target organ damage in older African Americans by Ammous, Farah, Zhao, Wei, Ratliff, Scott M., Kho, Minjung, Shang, Lulu, Jones, Alana C., Chaudhary, Ninad S., Tiwari, Hemant K., Irvin, Marguerite R., Arnett, Donna K., Mosley, Thomas H., Bielak, Lawrence F., Kardia, Sharon L.R., Zhou, Xiang, Smith, Jennifer

“…Target organ damage (TOD) manifests as vascular injuries in the body organ systems associated with long-standing hypertension. DNA methylation in peripheral…”
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Association of Mitochondrial DNA Copy Number With Brain MRI Markers and Cognitive Function: A Meta-analysis of Community-Based Cohorts by Zhang, Yuankai, Liu, Xue, Wiggins, Kerri L., Kurniansyah, Nuzulul, Guo, Xiuqing, Rodrigue, Amanda L, Zhao, Wei, Yanek, Lisa R, Ratliff, Scott M., Pitsillides, Achilleas, Aguirre Patiño, Juan Sebastian, Sofer, Tamar, Arking, Dan E., Austin, Thomas R., Beiser, Alexa S., Blangero, John, Boerwinkle, Eric, Bressler, Jan, Curran, Joanne E., Hou, Lifang, Hughes, Timothy M., Kardia, Sharon L, Launer, Lenore, Levy, Daniel, Mosley, Tom H., Nasrallah, Ilya M., Rich, Stephen S., Rotter, Jerome I., Seshadri, Sudha, Tarraf, Wassim, González, Kevin A., Ramachandran, Vasan, Yaffe, Kristine, Nyquist, Paul A, Psaty, Bruce M, DeCarli, Charles S., Smith, Jennifer A, Glahn, David C, González, Hector M, Bis, Joshua C, Fornage, Myriam, Heckbert, Susan R., Fitzpatrick, Annette L., Liu, Chunyu, Satizabal, Claudia L.

“…Previous studies suggest that lower mitochondrial DNA (mtDNA) copy number (CN) is associated with neurodegenerative diseases. However, whether mtDNA CN in…”
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Epigenetic loci for blood pressure are associated with hypertensive target organ damage in older African Americans from the genetic epidemiology network of Arteriopathy (GENOA) study by Kho, Minjung, Zhao, Wei, Ratliff, Scott M, Ammous, Farah, Mosley, Thomas H, Shang, Lulu, Kardia, Sharon L R, Zhou, Xiang, Smith, Jennifer A

“…Hypertension is a major modifiable risk factor for arteriosclerosis that can lead to target organ damage (TOD) of heart, kidneys, and peripheral arteries. A…”
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Accelerated DNA methylation age and medication use among African Americans by Kho, Minjung, Wang, Yi Zhe, Chaar, Dima, Zhao, Wei, Ratliff, Scott M., Mosley, Thomas H., Peyser, Patricia A., Kardia, Sharon L.R., Smith, Jennifer A.

“…DNA methylation age acceleration, the discrepancy between epigenetic age and chronological age, is associated with mortality and chronic diseases, including…”
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New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders by Evangelou, Evangelos, Gao, He, Chu, Congying, Ntritsos, Georgios, Blakeley, Paul, Butts, Andrew R., Pazoki, Raha, Suzuki, Hideaki, Koskeridis, Fotios, Yiorkas, Andrianos M., Karaman, Ibrahim, Elliott, Joshua, Luo, Qiang, Aeschbacher, Stefanie, Bartz, Traci M., Baumeister, Sebastian E., Braund, Peter S., Brown, Michael R., Brody, Jennifer A., Clarke, Toni-Kim, Dimou, Niki, Faul, Jessica D., Homuth, Georg, Jackson, Anne U., Kentistou, Katherine A., Joshi, Peter K., Lemaitre, Rozenn N., Lind, Penelope A., Lyytikäinen, Leo-Pekka, Mangino, Massimo, Milaneschi, Yuri, Nelson, Christopher P., Nolte, Ilja M., Perälä, Mia-Maria, Polasek, Ozren, Porteous, David, Ratliff, Scott M., Smith, Jennifer A., Stančáková, Alena, Teumer, Alexander, Tuominen, Samuli, Thériault, Sébastien, Vangipurapu, Jagadish, Whitfield, John B., Wood, Alexis, Yao, Jie, Yu, Bing, Zhao, Wei, Arking, Dan E., Auvinen, Juha, Liu, Chunyu, Männikkö, Minna, Risch, Lorenz, Rotter, Jerome I., Snieder, Harold, Veijola, Juha, Blakemore, Alexandra I., Boehnke, Michael, Campbell, Harry, Conen, David, Eriksson, Johan G., Grabe, Hans J., Guo, Xiuqing, van der Harst, Pim, Hartman, Catharina A., Hayward, Caroline, Heath, Andrew C., Jarvelin, Marjo-Riitta, Kähönen, Mika, Kardia, Sharon L. R., Kühne, Michael, Kuusisto, Johanna, Laakso, Markku, Lahti, Jari, Lehtimäki, Terho, McIntosh, Andrew M., Mohlke, Karen L., Morrison, Alanna C., Martin, Nicholas G., Oldehinkel, Albertine J., Penninx, Brenda W. J. H., Psaty, Bruce M., Raitakari, Olli T., Rudan, Igor, Samani, Nilesh J., Scott, Laura J., Spector, Tim D., Verweij, Niek, Weir, David R., Wilson, James F., Levy, Daniel, Tzoulaki, Ioanna, Bell, Jimmy D., Matthews, Paul M., Rothenfluh, Adrian, Desrivières, Sylvane, Schumann, Gunter, Elliott, Paul

“…Excessive alcohol consumption is one of the main causes of death and disability worldwide. Alcohol consumption is a heritable complex trait. Here we conducted…”
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Epigenetics of single-site and multi-site atherosclerosis in African Americans from the Genetic Epidemiology Network of Arteriopathy (GENOA) by Ammous, Farah, Zhao, Wei, Lin, Lisha, Ratliff, Scott M, Mosley, Thomas H, Bielak, Lawrence F, Zhou, Xiang, Peyser, Patricia A, Kardia, Sharon L R, Smith, Jennifer A

“…DNA methylation, an epigenetic mechanism modulated by lifestyle and environmental factors, may be an important biomarker of complex diseases including…”
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SNP-by-CpG Site Interactions in ABCA7 Are Associated with Cognition in Older African Americans by Chaar, Dima L, Nguyen, Kim, Wang, Yi-Zhe, Ratliff, Scott M, Mosley, Thomas H, Kardia, Sharon L R, Smith, Jennifer A, Zhao, Wei

“…SNPs in confer the largest genetic risk for Alzheimer's Disease (AD) in African Americans (AA) after ε4. However, the relationship between and cognitive…”
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The Interplay of Epigenetic, Genetic, and Traditional Risk Factors on Blood Pressure: Findings from the Health and Retirement Study by Zhang, Xinman, Ammous, Farah, Lin, Lisha, Ratliff, Scott M, Ware, Erin B, Faul, Jessica D, Zhao, Wei, Kardia, Sharon L R, Smith, Jennifer A

“…The epigenome likely interacts with traditional and genetic risk factors to influence blood pressure. We evaluated whether 13 previously reported DNA…”
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DNA Methylation Mediates the Association Between Individual and Neighborhood Social Disadvantage and Cardiovascular Risk Factors by Wang, Yi Zhe, Zhao, Wei, Ammous, Farah, Song, Yanyi, Du, Jiacong, Shang, Lulu, Ratliff, Scott M, Moore, Kari, Kelly, Kristen M, Needham, Belinda L, Diez Roux, Ana V, Liu, Yongmei, Butler, Kenneth R, Kardia, Sharon L R, Mukherjee, Bhramar, Zhou, Xiang, Smith, Jennifer A

“…Low socioeconomic status (SES) and living in a disadvantaged neighborhood are associated with poor cardiovascular health. Multiple lines of evidence have…”
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