Search Results - "Ratia, M."

AVCRI104P3, a novel multitarget compound with cognition-enhancing and anxiolytic activities: Studies in cognitively poor middle-aged mice by Giménez-Llort, L., Ratia, M., Pérez, B., Camps, P., Muñoz-Torrero, D., Badia, A., Clos, M.V.

“…•Chronic treatment with AVCRI104P3 improved cognition-decline in 12-month-old mice.•Cognitive benefits were seen in both short- and long-term learning and…”
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P690: GENE MUTATIONAL PROFILE ASSOCIATED WITH TREATMENT FAILURE OR PROGRESSION IN CHRONIC MYELOID LEUKEMIA by Estrada, N., Xicoy, B., Cabezón, M., Marcé, S., Senin, A., Angona, A., Alonso, E., Ratia, M., Plensa, M. E., Buch, J., Ortín, X., Zamora, L.

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Huprine X and huperzine A improve cognition and regulate some neurochemical processes related with Alzheimer's disease in triple transgenic mice (3xTg-AD) by Ratia, M, Giménez-Llort, L, Camps, P, Muñoz-Torrero, D, Pérez, B, Clos, M V, Badia, A

“…Different studies have established that cholinergic neurodegeneration could be a major pathological feature of Alzheimer's disease (AD). Thus, enhancement of…”
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Behavioural effects and regulation of PKCα and MAPK by huprine X in middle aged mice by Ratia, M., Giménez-Llort, L., Camps, P., Muñoz-Torrero, D., Clos, MªV., Badia, A.

“…The behavioural effects of huprine X, a new anticholinesterasic inhibitor, as well as its effects on the regulation of protein kinase C (PKC), mitogen…”
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Isoquinoline Kelch-like ECH-Associated Protein 1‑Nuclear Factor (Erythroid-Derived 2)-like 2 (KEAP1-NRF2) Inhibitors with High Metabolic Stability by Lazzara, Phillip R, David, Brian P, Ankireddy, Aparna, Richardson, Benjamin G, Dye, Katherine, Ratia, Kiira M, Reddy, Sekhar P, Moore, Terry W

“…Pharmacological activation of NRF2 (nuclear factor erythroid 2-related factor 2) arises from blocking the interaction of NRF2 with its negative regulator,…”
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Mechanism of Allosteric Modulation of Nicotinamide Phosphoribosyltransferase to Elevate Cellular NAD by Ratia, Kiira M., Shen, Zhengnan, Gordon-Blake, Jesse, Lee, Hyun, Laham, Megan S., Krider, Isabella S., Christie, Nicholas, Ackerman-Berrier, Martha, Penton, Christopher, Knowles, Natalie G., Musku, Soumya Reddy, Fu, Jiqiang, Velma, Ganga Reddy, Xiong, Rui, Thatcher, Gregory R. J.

“…In aging and disease, cellular nicotinamide adenine dinucleotide (NAD+) is depleted by catabolism to nicotinamide (NAM). NAD+ supplementation is being pursued…”
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Acetylcholinesterase triggers the aggregation of PrP 106–126 by Pera, M., Román, S., Ratia, M., Camps, P., Muñoz-Torrero, D., Colombo, L., Manzoni, C., Salmona, M., Badia, A., Clos, M.V.

“…Acetylcholinesterase (AChE), a senile plaque component, promotes amyloid-β-protein (Aβ) fibril formation in vitro. The presence of prion protein (PrP) in…”
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The end of vertebroplasties by Ruiz Santiago, F, Pérez Abela, A L, Almagro Ratia, M M

“…In 2009, two clinical trials that questioned the usefulness of vertebroplasty for the treatment of osteoporotic fractures compared with conservative treatment…”
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A prolonged outbreak of Norwalk-like calicivirus (NLV) gastroenteritis in a rehabilitation centre due to environmental contamination by KUUSI, M., NUORTI, J. P., MAUNULA, L., TRAN MINH, N. N., RATIA, M., KARLSSON, J., VON BONSDORFF, C.-H.

“…An outbreak of Norwalk-like calicivirus (NLV) gastroenteritis occurred in a rehabilitation centre in southern Finland between December 1999 and February 2000…”
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Synthesis and Evaluation of Noncovalent Naphthalene-Based KEAP1-NRF2 Inhibitors by Lazzara, Phillip R, Jain, Atul D, Maldonado, Amanda C, Richardson, Benjamin, Skowron, Kornelia J, David, Brian P, Siddiqui, Zamia, Ratia, Kiira M, Moore, Terry W

“…The oxidative stress response, gated by the protein–protein interaction of KEAP1 and NRF2, has garnered significant interest in the past decade. Misregulation…”
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Mineral and bone disorder associated with Cacchi-Ricci disease by Ábalos-Medina, Gracia M, Fernández Rodríguez, Irene, del Mar Almagro Ratia, M, Fuentes Ellauri, M Auxiliadora

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Discovery of Nonlipogenic ABCA1 Inducing Compounds with Potential in Alzheimer’s Disease and Type 2 Diabetes by Ben Aissa, Manel, Lewandowski, Cutler T, Ratia, Kiira M, Lee, Sue H, Layden, Brian T, LaDu, Mary Jo, Thatcher, Gregory R. J

“…Selective liver X receptor (LXR) agonists have been extensively pursued as therapeutics for Alzheimer’s disease and related dementia (ADRD) and, for…”
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Effect of acetylcholinesterase inhibitors on AChE-induced PrP106-126 aggregation by Clos, M V, Pera, M, Ratia, M, Román, S, Camps, P, Muñoz-Torrero, D, Colombo, L, Salmona, M, Badia, A

“…Transmissible spongiform encephalopaties are caused by an extracellular surface protein, the scrapie prion protein (PrPsc), which is an aberrant form of normal…”
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Recovery of Historically Contaminated Watercourse Polluted by the Chemical Wood Industry: EROD Activity in Fish as Biomarker by Ratia, Heli M, Vehniäinen, Eeva-Riikka, Rusanen, Antti T, Oikari, Aimo O.J

“…Despite outstanding process alterations over decades, pulp- and paper-mill-contaminated sediments and continuing exposure by the effluents may still have…”
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Abstract 1063: G Protein 12 Alpha Subunit Covalent Binding To Alpha-snap And Its Potential Role In Von Willebrand Factor Secretion by Rusu, Luiza, Bloem, Laura J, Chen, Hui, Lee, Hyun, Ratia, Kiira M, Jayathilaka, Lasanthi, Carlier, Paul R, Minshall, Richard D

“…Abstract only Rationale: α-SNAP is part of a large 20S complex composed of 3 SNARE, 4 α-SNAP, and 6 N-ethylmaleimide sensitive factor proteins that together…”
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Benchmarking antibiotic use in Finnish acute care hospitals using patient case-mix adjustment by Kanerva, Mari, Ollgren, Jukka, Lyytikäinen, Outi

“…Objectives It is difficult to draw conclusions about the prudence of antibiotic use in different hospitals by directly comparing usage figures. We present a…”
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Behavioural effects and regulation of PKCa and MAPK by huprine X in middle aged mice by Ratia, M, Gimenez-Llort, L, Camps, P, Munoz-Torrero, D, Clos, MA[ordfV, Badia, A

“…The behavioural effects of huprine X, a new anticholinesterasic inhibitor, as well as its effects on the regulation of protein kinase C (PKC), mitogen…”
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Effect of huprine X on β-amyloid, synaptophysin and α7 neuronal nicotinic acetylcholine receptors in the brain of 3xTg-AD and APPswe transgenic mice by Hedberg, Monika M, Clos, M Victoria, Ratia, Miriam, Gonzalez, Daniel, Lithner, Christina Unger, Camps, Pelayo, Muñoz-Torrero, Diego, Badia, Albert, Giménez-Llort, Lydia, Nordberg, Agneta

“…Several studies implicate acetylcholinesterase (AChE) in the pathogenesis of Alzheimer's disease (AD), raising the question of whether inhibitors of AChE also…”
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Behavioural effects and regulation of PKCalpha and MAPK by huprine X in middle aged mice by Ratia, M, Giménez-Llort, L, Camps, P, Muñoz-Torrero, D, Clos, M V, Badia, A

“…The behavioural effects of huprine X, a new anticholinesterasic inhibitor, as well as its effects on the regulation of protein kinase C (PKC), mitogen…”
Get full text