Search Results - "Rathore, Aaina Singh"

The Role of PI3K/Akt and ERK in Neurodegenerative Disorders by Rai, Sachchida Nand, Dilnashin, Hagera, Birla, Hareram, Singh, Saumitra Sen, Zahra, Walia, Rathore, Aaina Singh, Singh, Brijesh Kumar, Singh, Surya Pratap

“…Disruption of Akt and Erk-mediated signal transduction significantly contributes in the pathogenesis of various neurodegenerative diseases (NDs), such as…”
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Neuroprotective Effect of Chlorogenic Acid on Mitochondrial Dysfunction-Mediated Apoptotic Death of DA Neurons in a Parkinsonian Mouse Model by Singh, Surya Pratap, Dilnashin, Hagera, Rathore, Aaina Singh, Zahra, Walia, Birla, Hareram, Rai, Sachchida Nand, Singh, Saumitra Sen, Singh, Richa

“…Mitochondrial dysfunction and oxidative stress characterize major factors involved in the activation of complex processes corresponding to apoptosis-mediated…”
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Inhibition of pan-Aurora kinase attenuates evoked and ongoing pain in nerve injured rats via regulating KIF17-NR2B mediated signaling by Uniyal, Ankit, Akhilesh, Singh Rathore, Aaina, Kumari Keshri, Priyanka, Pratap Singh, Surya, Singh, Sanjay, Tiwari, Vinod

“…[Display omitted] •Kinesins (KIF’s) are ATP driven nanomotors involved in the trafficking of nociceptors.•Tozasertib attenuates evoked and spontaneous…”
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Neuroprotection of Rotenone-Induced Parkinsonism by Ursolic Acid in PD Mouse Model by Zahra, Walia, Rai, Sachchida Nand, Birla, Hareram, Singh, Saumitra Sen, Rathore, Aaina Singh, Dilnashin, Hagera, Singh, Richa, Keswani, Chetan, Singh, Rakesh K, Singh, Surya Pratap

“…Parkinson's Disease (PD) is characterized by both motor and non-motor symptoms. The presynaptic neuronal protein, α-Synuclein, plays a pivotal role in PD…”
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Oleuropein confers neuroprotection against rotenone-induced model of Parkinson’s disease via BDNF/CREB/Akt pathway by Singh, Richa, Zahra, Walia, Singh, Saumitra Sen, Birla, Hareram, Rathore, Aaina Singh, Keshri, Priyanka Kumari, Dilnashin, Hagera, Singh, Shekhar, Singh, Surya Pratap

“…Major pathological features of Parkinson’s disease (PD) include increase in oxidative stress leading to the aggregation of α-synuclein, mitochondrial…”
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Neuroprotective effects of Withania somnifera in BPA induced-cognitive dysfunction and oxidative stress in mice by Birla, Hareram, Keswani, Chetan, Rai, Sachchida Nand, Singh, Saumitra Sen, Zahra, Walia, Dilnashin, Hagera, Rathore, Aaina Singh, Singh, Surya Pratap

“…Bisphenol A (BPA), a major endocrine disruptor and a xenobiotic compound is used abundantly in the production of polycarbonate plastics and epoxy resins. Human…”
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Anti-Parkinsonian effect of Mucuna pruriens and Ursolic acid on GSK3β/Calcium signaling in neuroprotection against Rotenone-induced Parkinsonism by Zahra, Walia, Birla, Hareram, Singh, Saumitra Sen, Rathore, Aaina Singh, Dilnashin, Hagera, Singh, Richa, Keshri, Priyanka Kumari, Singh, Shekhar, Singh, Surya Pratap

“…Background: Exposure of environmental toxin is linked to the onset of Parkinson's disease (PD), especially in majority of sporadic cases. One of such toxins,…”
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NF-κB-Mediated Neuroinflammation in Parkinson’s Disease and Potential Therapeutic Effect of Polyphenols by Singh, Saumitra Sen, Rai, Sachchida Nand, Birla, Hareram, Zahra, Walia, Rathore, Aaina Singh, Singh, Surya Pratap

“…Different animal and human studies from last two decades in the case of Parkinson’s disease (PD) have concentrated on oxidative stress due to increased…”
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Anti-inflammatory Activity of Ursolic Acid in MPTP-Induced Parkinsonian Mouse Model by Rai, Sachchida Nand, Zahra, Walia, Singh, Saumitra Sen, Birla, Hareram, Keswani, Chetan, Dilnashin, Hagera, Rathore, Aaina Singh, Singh, Rajan, Singh, Rakesh K., Singh, Surya Pratap

“…Neuroinflammation plays an important role in the progression of Parkinson’s disease (PD) and hence may represent a target for treatment. The drugs used…”
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Epigenetic Modulation in Parkinson’s Disease and Potential Treatment Therapies by Rathore, Aaina Singh, Birla, Hareram, Singh, Saumitra Sen, Zahra, Walia, Dilnashin, Hagera, Singh, Richa, Keshri, Priyanka Kumari, Singh, Surya Pratap

“…In the recent past, huge emphasis has been given to the epigenetic alterations of the genes responsible for the cause of neurological disorders. Earlier, the…”
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Lipid-Coated MCM-41 Mesoporous Silica Nanoparticles Loaded with Berberine Improved Inhibition of Acetylcholine Esterase and Amyloid Formation by Singh, Anurag Kumar, Singh, Saumitra Sen, Rathore, Aaina Singh, Singh, Surya Pratap, Mishra, Gaurav, Awasthi, Rajendra, Mishra, Sunil Kumar, Gautam, Vibhav, Singh, Santosh Kumar

“…Selective permeability of the blood–brain barrier limits effective treatment of neurodegenerative disorders. In the present study, brain-targeted lipid-coated…”
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HAT and HDAC: Enzyme with Contradictory Action in Neurodegenerative Diseases by Singh, Richa, Rathore, Aaina Singh, Dilnashin, Hagera, Keshri, Priyanka Kumari, Gupta, Nitesh Kumar, Prakash, Singh Ankit Satya, Zahra, Walia, Singh, Shekhar, Singh, Surya Pratap

“…In view of the increasing risk of neurodegenerative diseases, epigenetics plays a fundamental role in the field of neuroscience. Several modifications have…”
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Neuroprotection by Mucuna pruriens in Neurodegenerative Diseases by Zahra, Walia, Birla, Hareram, Singh, Saumitra Sen, Rathore, Aaina Singh, Dilnashin, Hagera, Singh, Richa, Keshri, Priyanka Kumari, Gautam, Priyanka, Singh, Surya Pratap

“…The medicinal plant Mucuna pruriens (Fabaceae) is widely known for its anti-oxidative and anti-inflammatory properties. It is a well-established drug in…”
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Neuroprotective Effects of Tinospora cordifolia via Reducing the Oxidative Stress and Mitochondrial Dysfunction against Rotenone-Induced PD Mice by Dilnashin, Hagera, Birla, Hareram, Keswani, Chetan, Singh, Saumitra Sen, Zahra, Walia, Rathore, Aaina Singh, Singh, Richa, Keshri, Priyanka Kumari, Singh, Surya Pratap

“…Oxidative stress and mitochondrial dysfunction are leading mechanisms that play a crucial role in the progression of Parkinson’s disease (PD). Tinospora…”
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Curcumin Modulates p62–Keap1–Nrf2-Mediated Autophagy in Rotenone-Induced Parkinson’s Disease Mouse Models by Rathore, Aaina Singh, Singh, Saumitra Sen, Birla, Hareram, Zahra, Walia, Keshri, Priyanka Kumari, Dilnashin, Hagera, Singh, Richa, Singh, Shekhar, Singh, Surya Pratap

“…Autophagy mediates self-digestion of abnormally aggregated proteins and organelles present in the cytoplasm. This mechanism may prove to be neuroprotective…”
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Unraveling the Neuroprotective Effect of Tinospora cordifolia in a Parkinsonian Mouse Model through the Proteomics Approach by Birla, Hareram, Keswani, Chetan, Singh, Saumitra Sen, Zahra, Walia, Dilnashin, Hagera, Rathore, Aaina Singh, Singh, Richa, Rajput, Monika, Keshri, Priyanka, Singh, Surya Pratap

“…Stress-induced dopaminergic (DAergic) neuronal death in the midbrain region is the primary cause of Parkinson’s disease (PD). Following the discovery of…”
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Quality Control in Huntington’s Disease: a Therapeutic Target by Rai, Sachchida Nand, Singh, Brijesh Kumar, Rathore, Aaina Singh, Zahra, Walia, Keswani, Chetan, Birla, Hareram, Singh, Saumitra Sen, Dilnashin, Hagera, Singh, Surya Pratap

“…Huntington’s disease (HD) is a fatal autosomal dominantly inherited brain disease caused by excessively expanded CAG repeats in gene which encodes huntingtin…”
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Correction to “Lipid-Coated MCM-41 Mesoporous Silica Nanoparticles Loaded with Berberine Improved Inhibition of Acetylcholine Esterase and Amyloid Formation” by Singh, Anurag Kumar, Singh, Saumitra Sen, Rathore, Aaina Singh, Singh, Surya Pratap, Mishra, Gaurav, Awasthi, Rajendra, Mishra, Sunil Kumar, Gautam, Vibhav, Singh, Santosh Kumar

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