Search Results - "Rathnayake, A."
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Distinctive roles of fibrillar collagen I and collagen III in mediating fibroblast-matrix interaction: A nanoscopic study
Published in Biochemical and biophysical research communications (30-06-2021)“…One major goal in tissue engineering is to create functional materials, mimicking scaffolds in native tissues, to modulate cell function for tissue repair…”
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Electrospun Silk Fibroin-CNT Composite Fibers: Characterization and Application in Mediating Fibroblast Stimulation
Published in Polymers (26-12-2022)“…Electrospinning is a simple, low-cost, and highly efficient technique to generate desirable nano/microfibers from polymer solutions. Silk fibroin (SF), a…”
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Visualizing Cholesterol in the Brain by On-Tissue Derivatization and Quantitative Mass Spectrometry Imaging
Published in Analytical chemistry (Washington) (23-03-2021)“…Despite being a critical molecule in the brain, mass spectrometry imaging (MSI) of cholesterol has been under-reported compared to other lipids due to the…”
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PHY34 inhibits autophagy through V-ATPase V0A2 subunit inhibition and CAS/CSE1L nuclear cargo trafficking in high grade serous ovarian cancer
Published in Cell death & disease (10-01-2022)“…PHY34 is a synthetic small molecule, inspired by a compound naturally occurring in tropical plants of the Phyllanthus genus. PHY34 was developed to have potent…”
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Distinctive structure, composition and biomechanics of collagen fibrils in vaginal wall connective tissues associated with pelvic organ prolapse
Published in Acta biomaterialia (15-10-2022)“…Collagen is the predominant structural protein within connective tissues. Pelvic organ prolapse (POP) is characterized by weakening of the pelvic floor…”
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Differential Proteomics Reveals miR-155 as a Novel Indicator of Liver and Spleen Pathology in the Symptomatic Niemann-Pick Disease, Type C1 Mouse Model
Published in Molecules (Basel, Switzerland) (12-03-2019)“…Niemann-Pick disease, type C1 (NPC1) is a rare, autosomal recessive, lipid storage disorder caused by mutations in . As a result, there is accumulation of…”
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Machine learning enabled multiplex detection of periodontal pathogens by surface-enhanced Raman spectroscopy
Published in International journal of biological macromolecules (01-02-2024)“…Periodontitis is a chronic inflammation of the periodontium caused by a persistent bacterial infection, resulting in destruction of the supporting structures…”
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Comparative Analysis of the Genetic Variants in Haematopoietic Stem/Progenitor and Mesenchymal Stem Cell Compartments in de novo Myelodysplastic Syndromes
Published in Blood cells, molecules, & diseases (01-05-2021)“…Myelodysplastic Syndromes (MDS) are hematological clonal disorders. Bone marrow (BM) mesenchymal stem cells (MSCs) interact with the haematopoietic stem and…”
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Porous Crumb Structure of Leavened Baked Products
Published in International journal of food science (2018)“…Quality evaluation of the porous crumb structure of leavened baked goods, especially bread, has become a vast study area of which various research studies have…”
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Genetic diversity, phylogenetic and phylogeographic analysis of Anopheles culicifacies species complex using ITS2 and COI sequences
Published in PloS one (16-08-2023)“…Anopheles culicifacies is the major vector of malaria in Sri Lanka and the Indian subcontinent which is characterized as a species complex with five sibling…”
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Characterization of β-secretase inhibitory extracts from sea cucumber (Stichopus japonicus) hydrolysis with their cellular level mechanism in SH-SY5Y cells
Published in European food research & technology (01-08-2021)“…Alzheimer’s disease (AD) is the main type of dementia found in the elderly population. The prevention of β-amyloid (Aβ) production by inhibiting β-secretase,…”
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Comparison of serum concentrations of interleukin-8 and carcinoembryonic antigen in a south Asian cohort of patients with colorectal cancer
Published in World cancer research journal (01-01-2023)“…OBJECTIVE: Colorectal cancer (CRC) is the third most common cancer type in the world. Carcinoembryonic antigen (CEA) is widely used as a marker for CRCs…”
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Age and sex related variations of adult human ocular volumes in the Sri Lankan population: an evaluation using magnetic resonance imaging
Published in Radiography (London, England. 1995) (01-01-2023)“…Variations in the human ocular volumes are related to ocular pathologies including congenital glaucoma, microphthalmus, buphthalmus, and macrophthalmus. As the…”
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Two new plant nutrient nanocomposites based on urea coated hydroxyapatite: Efficacy and plant uptake
Published in The Indian journal of agricultural sciences (01-04-2016)“…Macronutrient delivery to plants, particularly nitrogen, is problematic because of losses occurring during fertilization. Currently, nanotechnology is being…”
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Abstract NT-119: TARGET DISCOVERY OF NATURAL PRODUCT INSPIRED PHYLLANTHUSMINS FOR TREATMENT OF HIGH GRADE SEROUS OVARIAN CANCER
Published in Clinical cancer research (15-11-2019)“…Abstract BACKGROUND: High grade serous ovarian cancer (HGSOC) is a lethal gynecological malignancy with a need for new therapeutic agents. Many of the most…”
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Phenotypic and Cytogenetic Characterization of Mesenchymal Stromal Cells in De Novo Myelodysplastic Syndromes
Published in Analytical cellular pathology (Amsterdam) (2016)“…Bone marrow (BM) mesenchymal stem/stromal cells (MSCs) are vital in hematopoiesis. Whether BM-MSCs alter their characteristics in Myelodysplastic Syndromes…”
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Urea-Hydroxyapatite Nanohybrids for Slow Release of Nitrogen
Published in ACS nano (28-02-2017)“…While slow release of chemicals has been widely applied for drug delivery, little work has been done on using this general nanotechnology-based principle for…”
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Mapping ilmenite deposit in Pulmudai, Sri Lanka using a hyperspectral imaging-based surface mineral mapping method
Published in Journal of the National Science Foundation (30-09-2019)Get full text
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Hybrid supercapacitors based on metal organic frameworks using p-phenylenediamine building block
Published in Chemical engineering journal (Lausanne, Switzerland : 1996) (01-04-2019)“…[Display omitted] •Novel MOFs using p-phenylenediamine ligand for energy storage devices.•Green synthesis via liquid–liquid interfacial reaction at room…”
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Redox active multi-layered Zn-pPDA MOFs as high-performance supercapacitor electrode material
Published in Electrochimica acta (20-02-2019)“…Metal–organic frameworks (MOFs), which combine organic and inorganic components, are promising materials for energy storage. The conjugated structure of MOFs…”
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