Search Results - "Rathman, Benjamin M."

Late-Stage Sidechain-to-Backbone Macrocyclization of N‑Amino Peptides by Rathman, Benjamin M, Del Valle, Juan R

“…Cysteine-containing N-amino peptides undergo chemoselective reactions with haloaldehydes to afford ethylene-bridged cyclic peptides. This bis-alkylation…”
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Synthesis and biological evaluation of backbone-aminated analogues of gramicidin S by Rathman, Benjamin M., Allen, Jessie L., Shaw, Lindsey N., Del Valle, Juan R.

“…[Display omitted] We report the parallel synthesis of gramicidin S derivatives featuring backbone N-amino substituents. Analogues were prepared by…”
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Design and Synthesis of Biologically Relevant N-Aminated Macrocyclic Peptidomimetics by Rathman, Benjamin M

“…Protein-protein interactions play important roles at all levels of cellular organization and thus are therapeutically relevant targets for the treatment of a…”
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Fluoro-curcuminoids and curcuminoid-BF2 adducts: Synthesis, X-ray structures, bioassay, and computational/docking study by Laali, Kenneth K., Rathman, Benjamin M., Bunge, Scott D., Qi, Xin, Borosky, Gabriela L.

“…[Display omitted] •Synthesis of α-fluorinated curcuminoids by direct mono- and difluorination.•Synthesis of ring fluorinated curcuminoids.•Isolation and…”
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Mild conversion of propargylic alcohols to α,β-unsaturated enones in ionic liquids (ILs); a new ‘metal free’ life for the Rupe rearrangement by Nandi, Ganesh C., Rathman, Benjamin M., Laali, Kenneth K.

“…A mild and selective transition metal free protocol for the conversion of propargylic alcohols to cyclic and acyclic α,β-unsaturated enones via the Rupe…”
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Fluoro-curcuminoids and curcuminoid-BF^sub 2^ adducts: Synthesis, X-ray structures, bioassay, and computational/docking study by Laali, Kenneth K, Rathman, Benjamin M, Bunge, Scott D, Qi, Xin, Borosky, Gabriela L

“…A series of α-carbonyl fluorinated curcuminoids were synthesized by direct mono- and difluorination with Selectfluor (F-TEDA-BF4) at r.t. without using a base…”
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